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Pearl City, HI, United States

The University of Hawaiʻi - West Oʻahu, UHWO, or UH West Oʻahu, is one of ten branches of the University of Hawaiʻi system and is a public, co-ed, state university, with the newly built main campus located at 91-1001 Farrington Highway, in Kapolei, Hawaii.Officially opened in January 1976, the school has been fully accredited by the Western Association of Schools and Colleges since 1981. The school originally only offered upper division courses up until the Fall of 2007 when the school began offering courses across all four years of studies.UH West Oʻahu is the only public four-year university located in the West Oʻahu area, and offers courses and public service activities.A new campus opened in August 2012 for the 2012-2013 school year. It relocated the school from its former location adjacent to Leeward Community College, to a location just over 5 miles to the west-southwest in East Kapolei. Wikipedia.

Belatik A.,University of Quebec | Hotchandani S.,University of Quebec | Bariyanga J.,University of Hawaii-West Oahu | Tajmir-Riahi H.A.,University of Quebec
European Journal of Medicinal Chemistry | Year: 2012

Retinoids are effectively transported in the bloodstream via serum albumins. We report the complexation of bovine serum albumin (BSA) with retinol and retinoic acid at physiological conditions, using constant protein concentration and various retinoid contents. FTIR, CD and fluorescence spectroscopic methods and molecular modeling were used to analyze retinoid binding site, the binding constant and the effects of complexation on BSA stability and secondary structure. Structural analysis showed that retinoids bind BSA via hydrophilic and hydrophobic interactions with overall binding constants of K Ret-BSA = 5.3 (±0.8) × 10 6 M -1 and K Retac-BSA = 2.3 (±0.4) × 10 6 M -1. The number of bound retinoid molecules (n) was 1.20 (±0.2) for retinol and 1.8 (±0.3) for retinoic acid. Molecular modeling showed the participation of several amino acids in retinoid-BSA complexes stabilized by H-bonding network. The retinoid binding altered BSA conformation with a major reduction of α-helix from 61% (free BSA) to 36% (retinol-BSA) and 26% (retinoic acid-BSA) with an increase in turn and random coil structures indicating a partial protein unfolding. The results indicate that serum albumins are capable of transporting retinoids in vitro and in vivo. © 2011 Elsevier Ltd. All rights reserved. Source

Bourassa P.,University of Quebec at Trois - Rivieres | Bariyanga J.,University of Hawaii-West Oahu | Tajmir-Riahi H.A.,University of Quebec at Trois - Rivieres
Journal of Physical Chemistry B | Year: 2013

The binding sites of antioxidant polyphenols resveratrol, genistein, and curcumin are located with milk α- and β-caseins in aqueous solution. FTIR, CD, and fluorescence spectroscopic methods and molecular modeling were used to analyze polyphenol binding sites, the binding constant, and the effects of complexation on casein stability and conformation. Structural analysis showed that polyphenols bind casein via hydrophilic and hydrophobic interactions with the number of bound polyphenol molecules (n) 1.20 for resveratrol, 1.42 for genistein, and 1.43 for curcumin with α-casein and 1.14 for resveratrol, 1.27 for genistein, and 1.27 for curcumin with β-casein. The overall binding constants of the complexes formed are Kres-α-casein = 1.9 (±0.6) × 104 M-1, K gen-α-casein = 1.8 (±0.4) × 104 M -1, and Kcur-α-casein = 2.8 (±0.8) × 104 M-1 with α-casein and K res-β-casein = 2.3 (±0.3) × 104 M -1, Kgen-β-casein = 3.0 (±0.5) × 10 4 M-1, and Kcur-β-casein = 3.1 (±0.5) × 104 M-1 for β-casein. Molecular modeling showed the participation of several amino acids in polyphenol-protein complexes, which were stabilized by the hydrogen bonding network with the free binding energy of -11.56 (resveratrol-α-casein), -12.35 (resveratrol-β-casein), -9.68 (genistein-α-casein), -9.97 (genistein-β-casein), -8.89 (curcumin-α-casein), and -10.70 kcal/mol (curcumin-β-casein). The binding sites of polyphenols are different with α- and β-caseins. Polyphenol binding altered casein conformation with reduction of α-helix, indicating a partial protein destabilization. Caseins might act as carriers to transport polyphenol in vitro. © 2013 American Chemical Society. Source

Szymanski N.,University of Hawaii-West Oahu
Computers and Composition | Year: 2015

2013 marked the 30th anniversary, or birthday, of the Computers and Composition journal. In order to provide a reflective picture of where the computers and composition subdiscipline has been, what identities it has cultivated, and where it stands in relation to the larger field of composition, this study examines the articles published in College Composition and Communication (CCC) and Computers and Composition (C&C) from 1983-2011. This research identifies six major findings. The first five speak to the relationship dynamics between CCC and C&C: 1) the journals' overall publication relationship; 2) both journals' participation in a sticky theory-practice dance; 3) the ways each journal relates (or fails to relate) other subdisciplines to computers and composition; 4) the major topics displayed significantly in one journal and minimally in the other; and 5) both journals' overall trend of programmatic stasis and (slow) professional increase. This study's sixth finding presents an emerging trend in C&C: the slow and nuanced appearance of a sophisticated development from single to multiple points of entry in the journal's articles. Finally, these findings are put in dialogue with current assertions about the relationship between CCC and C&C to explore how they both align with and challenge previous assumptions. © 2015 Published by Elsevier Inc. Source

Turner J.W.,University of Hawaii-West Oahu
Human Biology | Year: 2013

The study of kinship systems has direct relevance for the field of human genetics and the study of microevolution in human populations. Some types of postmarital residence rules-rules requiring a married couple to live with or near relatives of the husband or wife-will have consequences for the distribution of mitochondrial DNA and Y chromosome lineages. Rules that proscribe or encourage marriage with close kin will also have consequences for allele frequency. A preference for marrying at a distance, both socially and geographically, creates alliances that can have survival value for individuals and groups in an environment of periodic or unpredictable scarcity. This article considers the nature of early contact between the indigenous foraging populations of the Philippines and Austronesian speaking settlers who began arriving ~4,500-4,000 BP. It argues that when the first Austronesians arrived they brought with them a kinship system based on symmetrical exchange between descent-based groups. It considers why such a system was gradually changed into the bilateral kinship systems that characterize the various peoples of the Philippines today, "negrito" and non-negrito alike. © 2013 Wayne State University Press. Source

DeLonge M.S.,Union of Concerned Scientists | Miles A.,University of Hawaii-West Oahu | Carlisle L.,University of California at Berkeley
Environmental Science and Policy | Year: 2016

Ecological impacts of industrial agriculture include significant greenhouse gas emissions, loss of biodiversity, widespread pollution by fertilizers and pesticides, soil loss and degradation, declining pollinators, and human health risks, among many others. A rapidly growing body of scientific research, however, suggests that farming systems designed and managed according to ecological principles can meet the food needs of society while addressing these pressing environmental and social issues. The promise of such systems implies an urgent need for increasing the scope and scale of this area of research - agroecology. Notably, agroecological systems have been shown to reduce input dependency and therefore related research is unlikely to be supported by the private sector. Yet, the amount of federal funding available for agroecology has remained unclear. To address this gap in knowledge, we identified projects beginning in 2014 from the USDA Current Research Information System (CRIS) database and searched key sections of project reports for major components emphasizing sustainable agriculture, including agroecology. Components were grouped into four levels according to their focus on: improving system efficiency to reduce the use of inputs (L1), substituting more sustainable inputs and practices into farming systems (L2), redesigning systems based on ecological principles (L3: agroecology), or reestablishing connections between producers and consumers to support a socio-ecological transformation of the food system (L4: social dimensions of agroecology). We identified 824 projects, which accounted for $294 million dollars: just over 10% of the entire 2014 USDA Research, Extension, and Economics (REE) budget. Using a highly conservative classification protocol, we found that the primary focus of many projects was unrelated to sustainable agriculture at any level, but the majority of projects had at least one relevant component (representing 52-69% of analyzed funds, depending on whether projects focused exclusively on increasing yields were included). Of the total $294 million of analyzed funds, 18-36% went to projects that included a L1 component. Projects including components in L2, L3, or L4 received just 24%, 15%, and 14% of analyzed funds, respectively. Systems-based projects that included both agroecological farming practices (L3) and support for socioeconomic sustainability (L4) were particularly poorly funded (4%), as were L3 projects that included complex rotations (3%), spatially diversified farms (3%), rotational or regenerative grazing (1%), integrated crop-livestock systems (1%), or agroforestry (<1%). We estimated that projects with an emphasis on agroecology, indicated by those with a minimum or overall level of L3, represented 5-10% of analyzed funds (equivalent to only 0.6-1.5% of the 2014 REE budget). Results indicate that increased funding is urgently needed for REE, especially for systems-based research in biologically diversified farming and ranching systems. © 2015 The Authors. Source

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