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Guelph, Canada

The University of Guelph, also known as U of G, is a comprehensive public research university in Guelph, Ontario, Canada. It was established in 1964 after the amalgamation of Ontario Agricultural College, the Macdonald Institute, and the Ontario Veterinary College, and has since grown to an institution of more than 21,000 students and academic staff. Wikipedia.

Whitfield C.,University of Guelph | Stephen Trent M.,University of Texas at Austin
Annual Review of Biochemistry

Lipopolysaccharide molecules represent a unique family of glycolipids based on a highly conserved lipid moiety known as lipid A. These molecules are produced by most gram-negative bacteria, in which they play important roles in the integrity of the outer-membrane permeability barrier and participate extensively in host-pathogen interplay. Few bacteria contain lipopolysaccharide molecules composed only of lipid A. In most forms, lipid A is glycosylated by addition of the core oligosaccharide that, in some bacteria, provides an attachment site for a long-chain O-antigenic polysaccharide. The complexity of lipopolysaccharide structures is reflected in the processes used for their biosynthesis and export. Rapid growth and cell division depend on the bacterial cell's capacity to synthesize and export lipopolysaccharide efficiently and in large amounts. We review recent advances in those processes, emphasizing the reactions that are essential for viability. Copyright © 2014 by Annual Reviews. Source

University of Guelph and Beth Israel Deaconess Medical Center | Date: 2014-03-11

The invention features thrombospondin-1 (TSP-1) polypeptides (e.g., 3TSR-Fc fusion proteins), nucleic acid molecules encoding the TSP-1 polypeptides, and compositions thereof. The invention also features methods of making and using the TSP-1 polypeptides of the invention (e.g., using 3TSR-Fc fusion proteins to treat a subject having a disorder associated with pathological angiogenesis, e.g., cancer, e.g., epithelial ovarian cancer (EOC)).

University of Guelph | Date: 2015-08-21

The present disclosure relates to novel pore-forming toxins of Type A

A high performance acrylonitrile butadiene styrene (ABS) polymer blend comprising ABS, polylactic acid (PLA), an acrylic copolymer based lubricant and a polymeric chain extender.

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