The Universidad de Guanajuato is a university based in the Mexican state of Guanajuato, made up of about 33,828 students in programs ranging from high school level to the doctorate level. Over 17,046 of those are pursuing undergraduate, masters, and doctorate degrees. The university offers 153 academic programs, including 13 doctorates, 39 masters programs, and 65 bachelor's degrees. The university has schools in fourteen cities throughout the state of Guanajuato. The University of Guanajuato boasts an academic staff recognized for its high quality. This staff carries out essential work in the areas of training, research and outreach.Because of its quality teachers and the unceasing efforts of its academic bodies, the University of Guanajuato carries out more scientific research than any other institution of higher education in the state; its academic units, institutes, and research centers develop projects with regional applications in benefit of all the citizens of Guanajuato. Wikipedia.
News Article | May 4, 2017
VIDEO: The fight against skin cancer just got a new weapon. For years, melanoma researchers have studied samples that were considered uniform in size and color, making them easier to examine... view more The fight against skin cancer just got a new weapon. For years, melanoma researchers have studied samples that were considered uniform in size and color, making them easier to examine by more conventional means. But melanomas don't always come in the same shape and hue; often, melanomas are irregular and dark, making them difficult to investigate. Now, researchers at the University of Missouri have devised a new tool to detect and analyze single melanoma cells that are more representative of the skin cancers developed by most patients. The study, recently reported in Analyst published by the Royal Society of Chemistry, outlines the new techniques that could lead to better and faster diagnoses for the life-threatening disease. "Researchers often seek out the types of cancerous cells that are homogenous in nature and are easier to observe with traditional microscopic devices," said Luis Polo-Parada, an Associate Professor of Medical Pharmacology and Physiology and an investigator at Mizzou's Dalton Cardiovascular Research Center. "Yet, because the vast amount of research is conducted on one type of cell, it often can lead to misdiagnosis in a clinical setting." The team that included Gary Baker, an assistant professor of chemistry in the MU College of Arts and Science and Gerardo Gutierrez-Juarez, a professor and investigator at the University of Guanajuato in Mexico, decided to supplement an emerging technique called photoacoustic (PA) spectroscopy, a specialized optical technique that is used to probe tissues and cells non-invasively. Current systems use the formation of sound waves followed by the absorption of light which means that the tissues must adequately absorb the laser light. This is why, up until now, researchers have focused only on strong-light-absorb cells melanoma cells, Polo-Parada said. The team modified a microscope that was able to merge light sources at a range conducive to observing the details of single melanoma cells. Using the modified system, human melanoma and breast cancers as well as mouse melanoma cells were diagnosed with greater ease and efficiency. The team also noted that as the cancer cells divided, they grew paler in color but the system was able to detect the newer, smaller cells as well. "Overall, our studies show that by using modified techniques we will be able to observe non-uniform cancer cells, regardless of their origin," Polo-Parada said. "Additionally, as these melanoma cells divide and distribute themselves throughout the blood, they can cause melanomas to metastasize. We were able to observe those cancers as well. This method could help medical doctors and pathologists to detect cancers as they spread, becoming one of the tools in the fight against this fatal disease." The study, "Spectrophotometric analysis at the single-cell level: elucidating dispersity within melanic immortalized cell populations," was supported in part by the Mizzou Advantage program, an initiative that fosters interdisciplinary collaboration among faculty, staff, students and external partners to solve real-world problems in four areas of strength identified at the University of Missouri, including Food for the Future, One Health/One Medicine, Sustainable Energy and Media of the Future. Ellison Gordon from the Mizzou Machine Shop was involved in the manufacturing of components for the microscope setup.
Mexican Institute of Petroleum and University of Guanajuato | Date: 2014-10-22
The present invention relates to the use of a chemical composition to modify the physical properties (viscosity and interfacial tension) of heavy and extra-heavy crude oils, to increase their mobility. The chemical composition comprises or consists of a combination of systems based on ionic and non-ionic liquids, which may be pure or modified, mixed in an aqueous or organic medium as a dispersing agent, depending on the nature of the crude to be treated, together with a surfactant. The composition is mixed with the crude oil at a temperature between 5 and 100 C., at pressures from 1 atm (14.7 psi) up to about 680.2 atm (10,000 psi). The composition can be mixed with heavy crude oils, at the point of extraction from the well in the field, during the transport of crude oil in pipelines, or in the well discharge pipelines.
Shmaliy Y.S.,University of Guanajuato
IEEE Transactions on Signal Processing | Year: 2011
We address a p-shift finite impulse response (FIR) unbiased estimator (UE) for linear discrete time-varying filtering (p=0), p-step prediction (p<0), and p-lag smoothing (p<0) in state space with no requirements for initial conditions and zero mean noise. A solution is found in a batch form and represented in a computationally efficient iterative Kalman-like one. It is shown that the Kalman-like FIR UE is able to outperform the Kalman filter if the noise covariances and initial conditions are not known exactly, noise is not white, and both the system and measurement noise components need to be filtered out. Otherwise, the errors are similar. Extensive numerical studies of the FIR UE are provided in Gaussian and non-Gaussian environments with outliers and temporary uncertainties. © 2011 IEEE.
Shmaliy Y.S.,University of Guanajuato
IEEE Transactions on Signal Processing | Year: 2010
This paper addresses a general $p$-shift linear optimal finite impulse response (FIR) estimator intended for solving universally the problems of filtering (p=0), smoothing (p < 0), and prediction (p > 0) of discrete time-invariant models in state space. An optimal solution is found in the batch form with the initial mean square state function self-determined by solving the discrete algebraic Riccati equation. An unbiased solution represented both in the batch and recursive forms does not involve any knowledge about noise and initial state. The mean square errors in both the optimal and unbiased estimates are found via the noise power gain (NPG) and a recursive algorithm for fast computation of the NPG is supplied. Applications are given for FIR filtering with fixed, receding, and full averaging horizons. © 2010 IEEE.
Zaina S.,University of Guanajuato
Current Opinion in Lipidology | Year: 2014
PURPOSE OF REVIEW: Epigenetic mechanisms of transcriptional regulation in atherosclerosis have gained an increasing interest in recent years. We focus on the relevance of DNA methylation, a well characterized epigenetic modification of the genome, as a biomarker and underlying mechanism of atherosclerosis. RECENT FINDINGS: A growing number of loci have been identified, which are good candidate biomarkers for atherosclerosis and provide novel insights into the molecular changes taking place in the diseased vessel. Understanding the global change in DNA methylation during atherosclerosis remains a challenge. Novel unfolding research avenues include the interplay between genetic variants and DNA methylation patterns, and the role of long noncoding RNAs as epigenetic regulators. SUMMARY: Epigenetics continues to represent a promising area of research in atherosclerosis. The full exploitation of cutting edge epigenomics will be decisive to define whether epigenetics will contribute to lower the burden of cardiovascular diseases. © 2014 Wolters Kluwer Health Lippincott Williams & Wilkins.
Urena-Lopez L.A.,University of Guanajuato
Physical Review D - Particles, Fields, Gravitation and Cosmology | Year: 2014
We derive nonrelativistic equations of motion for the formation of cosmological structure in a scalar field dark matter (SFDM) model corresponding to a complex scalar field endowed with a quadratic scalar potential. Starting with the equations of motion written in the Newtonian gauge of scalar perturbations, we separate out the involved fields into relativistic and nonrelativistic parts and find the equations of motion for the latter that can be used to build up the full solution. One important assumption will be that the SFDM field is in the regime of fast oscillations, under which its behavior in the homogeneous regime is exactly that of cold dark matter. The resultant equations are quite similar to the Schrödinger-Poisson system of Newtonian boson stars plus relativistic leftovers, and they can be used to study the formation of cosmological structure in SFDM models, and others alike, to ultimately prove their viability as complete dark matter models. © 2014 American Physical Society.
University of Guanajuato | Date: 2014-05-21
This invention describes the method to produce solid heterogeneous chiral organocatalysts which can be used in condensation reactions. The catalysts can be recovered in a simple manner by means of filtration and also be reused.
University of Guanajuato | Date: 2013-12-02
This invention includes agents and compositions having MRI, PET, CT, X-ray, SPECT or optical signals, and methods for their use in the determination of a target. In some cases, a MRI, PET, CT, X-ray, SPECT, optical or other signal produced by the agent or composition can be affected by the presence of the target. Examples of targets that can be determined by this invention include, but are not limited to zinc, copper, iron ions and other biological targets. Example of application for imaging in vivo includes the function of pancreas and other organs.
University of Guanajuato | Date: 2013-11-20
This invention describes the methodology to produce solid heterogeneous chiral organocatalysts that can be used in condensation reactions. The catalysts can be recovered in a simple manner by filtration and can also be reused.
Shmaliy Y.S.,University of Guanajuato
IEEE Transactions on Signal Processing | Year: 2012
The first- and second-order extended finite impulse response (EFIR1 and EFIR2, respectively) filters are addressed for suboptimal estimation of nonlinear discrete-time state-space models with additive white Gaussian noise. It is shown that, unlike the extended Kalman filter (EKF) and EFIR2 filter, the EFIR1 one does not require noise statistics and initial errors. Only within a narrow region around actual noise covariances, EFIR filters fall a bit short of EKF and they demonstrate better performance otherwise. It is shown that the optimal averaging interval for EFIR filters can be determined via measurement without a reference model in a learning cycle. We also notice that the second-order approximation can improve the local performance, but it can also deteriorate it. We thus have no recommendations about its use, at least for tracking considered as an example of applications. © 1991-2012 IEEE.