Granada, Spain

University of Granada

www.ugr.es
Granada, Spain

The University of Granada is a public university located in the city of Granada that enrolls approximately 80,000 students, thereby becoming the fourth largest university in Spain. UGR also has campuses in Northern Africa , thus being the only European university with campuses in two continents. Founded in 1531 by Emperor Charles V, UGR has almost 500 years of history and it is one of the most famous universities in Spain.According to several rankings, the University of Granada ranks among top ten best Spanish universities and holds first place in Translation and Interpreting studies. In addition, UGR plays a major role in scientific output, placing high in national ranks and being one of the best world universities in computing and mathematics studies. The university has an important heritage thanks to its policy of using buildings of historical and cultural value. The Madrasah of Granada represents one such example. Furthermore, the university has major new facilities committed to innovation, such as the Parque Tecnológico de Ciencias de la Salud.Every year, over 2,000 European students enroll in UGR through the Erasmus Programme, making it the most popular European destination. The university's Center for Modern Languages receives over 10,000 international students each year. UGR also has been recently voted best Spanish university by international students. Wikipedia.

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The invention relates to the use of microorganisms as plant growth stimulants and for the biological control of bacterium, insects, fungi and phytopathogenic nematodes. More specifically, the invention relates to the use of microorganisms of the genus Bacillus, more specifically the Bacillus methylotrophicus species, as well as to cultures thereof, compositions comprising these bacteria, different culture methods and the products comprising same, as plant growth stimulants and for the biological control of bacterium, insects, fungi and phytopathogenic nematodes.


The present invention provides an in vitro method of detecting circulating tumour cells, circulating tumour cells of epithelial phenotype and circulating tumour cells of epithelial to mesenchymal transition (EMTs), in a biological sample using, as an indicator, expression levels of miRNA-21, and obtaining a result of the method by comparing the expression levels of said miRNA-21 with a negative control or with a positive control, wherein if the expression levels in the cells of the biological sample are over-expressed in comparison to a negative control is indicative of the presence of circulating tumour cells in said biological sample or wherein if the expression levels in the cells of the biological sample are expressed in an amount greater than 2/3 of the maximum expression achieved in a positive control is indicative of the presence of circulating tumour cells in said biological sample.


Patent
Servicio Andaluz De Salud and University of Granada | Date: 2017-02-01

The invention relates to an aqueous melatonin composition exhibiting surprising long-term stability and allowing high concentrations of said water-insoluble active ingredient. The properties of said composition render it useful as an injectable, for example, for the intravenous administration thereof.


Patent
University of Granada and Servicio Andaluz De Salud | Date: 2015-08-04

The present invention relates to a serum-free conditioned medium that solves the drawbacks mentioned in the prior art, as it does not require prior handling of the cells, and it furthermore allows starting from a large population with no additional cost. This medium favors in vitro proliferation and conservation of the pluripotency potential that allows maintaining a state that is undifferentiated with respect to the subpopulation of cancer stem cells (CSCs) and in turn does not allow survival of the differentiated cells.


Patent
Stichting Vumc and University of Granada | Date: 2015-04-21

Disclosed are small ncRNAs that may be used as biomarkers for classifying the health status of an individual. The disclosure also provides screening methods for identifying ncRNA biomarkers.


The invention relates to the use of microorganisms as plant growth stimulants and for the biological control of bacterium, insects, fungi and phytopathogenic nematodes. More specifically, the invention relates to the use of microorganisms of the genus Bacillus, more specifically the Bacillus methylotrophicus species, as well as to cultures thereof, compositions comprising these bacteria, different culture methods and the products comprising same, as plant growth stimulants and for the biological control of bacterium, insects, fungi and phytopathogenic nematodes.


Patent
Stichting Vumc and University of Granada | Date: 2017-03-08

The present disclosure provides small ncRNAs as biomarkers for classifying the health status of an individual. The disclosure also provides screening methods for identifying ncRNA biomarkers.


Patent
University of Granada and Servicio Andaluz De Salud | Date: 2017-06-21

The present invention relates to a serum-free conditioned medium that solves the drawbacks mentioned in the prior art, as it does not require prior handling of the cells, and it furthermore allows starting from a large population with no additional cost. This medium favors in vitro proliferation and conservation of the pluripotency potential that allows maintaining a state that is undifferentiated with respect to the subpopulation of cancer stem cells (CSCs) and in turn does not allow survival of the differentiated cells.


Patent
Servicio Andaluz De Salud and University of Granada | Date: 2015-03-27

The invention relates to an aqueous melatonin composition exhibiting surprising long-term stability and allowing high concentrations of said water-insoluble active ingredient. The properties of said composition render it useful as an injectable, for example, for the intravenous administration thereof.


Patent
University of Granada, Servicio Andaluz De Salud and National University of Cordoba | Date: 2017-09-27

The invention is comprised in the field of biomedicine, and more specifically, the field of tissue engineering. The invention specifically relates to the use of multiple magnetic domain particles that have a mean diameter greater than 25 nm, to compositions and biomaterials comprising same, and to an in vitro method for producing an artificial tissue with the magnetic particles, to the artificial tissue that can be produced by said method, and to the use of said artificial tissue for partially or completely increasing, restoring or replacing the functional activity of a damaged organ or tissue.

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