Osman R.E.,Medcinal and Aromatic Plants Research Institute |
Elnima E.I.,University of Khartoum |
Omer M.E.A.,University of Elnilin
Journal of Medical Sciences (Faisalabad) | Year: 2013
Waltheria indica used by traditional healer in Sudan for treatment of many diseases. In this study antibacterial activity, toxicological and pharmacological screen of methanolic extracts of Weltheria indica roots was reported. One hundred eighty clinical isolates were obtained from diabetic wound infection, 30 Escherichia coli, 15 Klebsiella pneumoniae, 45 Proteus sp. 15 Pseudomonas aeruginosa, 60 Staphylococcus aureus and 15 Staphylococcus epidermidis. Cup-plate method used for antibacterial activity and the extract had an inhibitory effect against (91.7%) of the isolates. In the toxicity studies the results indicate that the LD50 of the extracts was more than 2000 mg kg-1. The extract had no effect on smooth muscle and skeletal muscle. The result of this study indicated that the methanolic extract of Waltheria indica roots with high antibacterial activity. In the toxicity study the result indicate that LD50 of the extract was more than 2000 mg kg-1 and the pharmacology study indicated at least the safety of the extract regarding the studied tissues.
Mohmad A.H.,University of Khartoum |
Gadour M.O.,Islamic University |
Omer F.Y.,Islamic University |
Ali A.B.M.,University of Elnilin |
And 5 more authors.
Scientific Research and Essays | Year: 2010
This non interventional descriptive study was conducted at El shaab Teaching Hospital during the period of Feb 2004 to Aug 2008, 720 adult Sudanese epileptic patients were included in the study, during the period of the study, 40 non epileptic patients (NES) were seen in the outpatient clinic with abnormal movement and were diagnosed as pseudoepilepsy. Forty (10 M; 30 F) patients with NES, 720 (390 M; 330 F) patients with epilepsy and 40 (15 M; 25 F) control subjects were recruited. Our preliminary results confirm previous researches showing that NES typically manifest between 20 and 30 years of age and that approximately three-quarters of all patients were women. The incidence of childhood sexual abuse varies considerably (10%), likewise the incidence of cerebral pathology (5%), the sexual coloring of the attack (4%); the frequency of psychogenic seizures combined with epilepsy (50%), the number of patients with pseudoepilepsy who remain on anticonvulsive medication (50%). All patients with pseudoepilepsy had normal EEG (electroencephalogram) and normal serum prolactin level. Pseudoepilepsy is not uncommon among adult Sudanese epileptic patients. © 2010 Academic Journals.
Hussein A.,University of Khartoum |
Fatah T.A.,Federal Ministry of Health |
Sidig A.,University of Elnilin |
Hamad A.,University of Bahr Elgazal |
And 5 more authors.
International Journal of Physical Sciences | Year: 2011
Diabetic autonomic neuropathy can cause cardiac, gastrointestinal, genitourinary and metabolic disorders. Strict glycemic control can slow the onset of diabetic autonomic neuropathy and sometimes reverse it. The study was aimed at investigating the presence of diabetic autonomic neuropathy in a group of Sudanese diabetic patients. This is a descriptive prospective cross-sectional study. It was conducted at Herra medical center and Alnoor specialized center in Omdurman. One hundred diabetic patients were studied using standardized questionnaire, including history, clinical examination and investigations. Female to male ratio was 1.7:1. Most of the patients had Type 1 Diabetes mellitus (DM). Common age group affected was >51 years and common duration of DM was < 10 years. Diabetic autonomic neuropathy was diagnosed in 71% of the patients. The majority of the patients had early stage diabetic autonomic neuropathy. Diabetic autonomic neuropathy is a very common problem among our studied group (all the patients were adult diabetic Sudanese). Diabetic autonomic neuropathy can occur at any age and at any time, even at early diagnosis of diabetes but poor glycemic control is the main implicating factor. All diabetic patients have to do annual expiration/inspiration ratio to detect early stages of diabetic autonomic neuropathy. © 2011 Academic Journals.