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Dubrovnik, Croatia

The University of Dubrovnik is a university located in Dubrovnik, Croatia. It has its roots in various successive institutions dedicated to the teaching of maritime engineering and naval architecture. In 1996, in recognition of the city's maritime traditions, the Polytechnic was established and was later given full university status in 2003. The University has since diversified its courses but the maritime science remains its traditional strength. Wikipedia.

Krile S.,University of Dubrovnik
Polish Maritime Research | Year: 2013

We need a better transport planning tool for loading maximization and transport cost minimization on the voyage route with multiple loading/unloading (discharging) ports. The implemented heuristic algorithm is able to find out an appropriate routing sequence with maximal earnings and profit. In the same time it looks for minimal loading/discharging and transshipment costs, but with fulfillment of cargo demands in a number of ports on the route. The efficient algorithm for optimal transport of N cargo loads (e.g. contingent of containers) for ships with limited capacity is being developed. This efficient tool may significantly reduce transport costs and ensure maximal profit to freight forwarders. Also, it can be applied for supply chain management of different goods from numerous vendors. The proposed algorithm shows acceptable complexity that means that such optimization tool can be used in shipping supported with limited computing power. © Elsevier BV 2013. Source

Nowadays, hereditary diseases are viewed through molecular mechanisms, and one of them, which keeps occurring rather frequently in medical publications, has been named after the Island of Mljet. The world first learned about mal de Meleda from a Dubrovnik physician Luka Stulli in 1826. He described it in a number of his island patients as a non-contagious hereditary skin disease, and named it mal de Meleda (a disease of Mljet). After Stulli, numerous scientists continued to investigate its aetiology and distinctive properties, introducing new scientific procedures to research the disease. The article keeps track of the way people and medicine perceived and treated mal de Meleda patients, starting from the early 19th century to the present day. It pays special attention to how the disease was perceived and described in medical literature through history. There are no reports in writing about the disease before the 19th century, but in oral tradition it was perceived as a punishment for the sins of sacrilege, sins of piracy, or even as leftovers of leprosy brought by the crusaders. We investigated if these legends have any support in preserved historical documents and to what extent they are related to real historical events and circumstances. Influenced by the booming research in microbiology, end 19th century physicians believed the disease was an isolated focus of leprosy. However, early 20th century physicians defined it as a hereditary skin disease with changes which distinguish it from other skin conditions. Genetic nature of the disease was later confirmed by molecular science. As for its geographical origin, the most recent medical research has shown that mal de Meleda is not restricted to the island of Mljet, and that it is spread worldwide, particularly in regions that, historically, were the trading routes of the Dubrovnik Republic. This implies that the mutation has spread through migration and persists only because it is not lethal and does not affect reproduction. Source

Pooh R.K.,Osaka International University | Kurjak A.,University of Dubrovnik
Journal of Perinatal Medicine | Year: 2015

Recent development of three-dimensional (3D) high definition (HD) ultrasound has resulted in remarkable progress in visualization of early embryos and fetuses in sonoembryology. The new technology of HDlive assesses both structural and functional developments in the first trimester with greater reliably than two-dimensional (2D) ultrasound. The ability to visualize not only fetal face, hands, fingers, feet, and toes, but also amniotic membranes, is better with volumetric ultrasound than 2D ultrasound. In this article, detailed and comprehensive structures of normal and abnormal fetuses depicted by 3D HDlive are presented, including various faces of Down's syndrome and holoprosencephaly, as well as low-set ear and finger/toe abnormalities from the first trimester. Three-dimensional HDlive further "humanizes" the fetus, enables detailed observation of the fetal face in the first trimester as shown in this article, and reveals that a small fetus is not more a fetus but a "person" from the first trimester. There has been an immense acceleration in understanding of early human development. The anatomy and physiology of embryonic development is a field where medicine exerts greatest impact on early pregnancy at present, and it opens fascinating aspects of embryonic differentiation. Clinical assessment of those stages of growth relies heavily on 3D/four-dimensional (4D) HDlive, one of the most promising forms of noninvasive diagnostics and embryological phenomena, once matters for textbooks are now routinely recorded with outstanding clarity. New advances deserve the adjective "breathtaking", including 4D parallel study of the structural and functional early human development. Source

Pooh R.K.,CRIFM Clinical Research Institute of Fetal Medicine PMC | Kurjak A.,University of Dubrovnik
Journal of Maternal-Fetal and Neonatal Medicine | Year: 2012

The introduction of 3D/4D sonography with high frequency transvaginal transducer has resulted in remarkable progress in ultrasonographic visualization of early embryos and fetuses and development of new fields of 3D sonoembryology. With the proper use of this new diagnostic modality and with experienced examiner, both structural and functional development in the first trimester of gestation can be assessed more objectively and reliable. Indeed new technology moved embryology from postmortem studies to the in vivo environment. Furthermore, there are good reasons to believe that 3D/4D sonography moved prenatal diagnosis of fetal abnormalities from the second to the first trimester of pregnancy. We will try to illustrate it with the number of convincing slides. © 2012 Informa UK, Ltd. Source

In this paper the efficient algorithm for optimal transport of different loads (e.g. contingent of containers) for ships with limited capacity is being developed. We need better transport planning and transport costs minimization on a voyage route with multiple loading ports and multiple ports of discharge (unloading). The goal is to improve vessel's capacity by choosing convenient freights and thus achieving greater profit. Such innovations in the logistics of transport might improve technology of seaborne trade, but also be used in the management of forwarding agent's chains for various types of goods. Source

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