The University of Delhi is a public central university located in Delhi, India. It is the premier university of the country and is known for its high standards in teaching and research, as well as the eminent scholars it attracts to its faculty.It was established in 1922 as a unitary, teaching and residential university by an Act of the then Central Legislative Assembly. The President of India is the Visitor, the Vice President is the Chancellor and the Chief Justice of the Supreme Court of India is the Pro-Chancellor of the University. Ever since its inception, a strong commitment to excellence in teaching and research has made the University of Delhi a role-model and path-setter for other universities in the country. Its rich academic tradition has always attracted the most talented students who later on go on to make important contributions to their society. Wikipedia.
News Article | May 15, 2017
Amidst acrimonious debate over the safety of genetically modified (GM) food crops, India’s top biotechnology regulator last week declared a transgenic mustard plant “safe for consumption.” Moving the plant into farmers’ fields is now a political decision in the hands of India’s environment minister, who may wait until the Supreme Court of India resolves several long-pending related cases. The GM mustard has been under development for almost a decade. A report assessing the plant’s risks was released a year ago, drawing some 700 comments that were reviewed by the Ministry of Environment’s Genetic Engineering Appraisal Committee (GEAC). The report concluded the mustard was safe and nutritious, and GEAC chair Amita Prasad in New Delhi says the commission unanimously agreed on 11 May to recommend allowing farmers to plant the crop for the next 4 years. The final decision will be made by Environment Minister Anil Dave. The GM mustard was developed with public funding by plant scientist Deepak Pental of the University of Delhi. His team introduced several genes from a soil bacterium, Bacillus amyloliquefaciens, into the mustard to facilitate hybridization. Mustard is largely a self-pollinating crop and creating high-yield hybrids has been cumbersome. If approved, Dhara Mustard Hybrid-11 (DMH-11) will be the second GM plant—but the first food crop—to reach India’s farmers. In 2004 India allowed commercial cultivation of GM cotton and it now accounts for more than 90% of the nation’s harvest. In 2010, GM eggplant also cleared GEAC’s review, but then–Environment Minister Jairam Ramesh put an indefinite moratorium on its introduction citing safety concerns. The New Delhi–based Coalition for a GM-free India is fighting the introduction of the transgenic mustard. The group blasted the GEAC’s decision, claiming in a letter to Dave that the committee “has shown itself to be anti-science, anti-farmers, anti-environment and anti-consumers.” Sources indicate that the minister may delay a decision until India’s Supreme Court rules in cases, pending since 2005, that question the safety of GM crops. The court has set no date for issuing a decision.
News Article | May 22, 2017
The International Association of HealthCare Professionals is pleased to welcome Dr. Toniya Singh, MD, FACC, Cardiologist to their prestigious organization with her upcoming publication in The Leading Physicians of the World. She is a highly trained and qualified physician with an extensive expertise in all facets of her work. Dr. Singh has been in practice for more than a decade and is currently serving patients within Saint Louis Heart and Vascular in Saint Louis, Missouri. She is also affiliated with Christian Hospital, DePaul Health Center, and the Gateway Regional Medical Center. Dr. Singh’s career in medicine began in 1994 when she graduated with her Medical Degree from Lady Hardinge Medical College at the University of Delhi in New Delhi, India. Upon relocating to the United States, she completed her residency and Cardiology fellowship at St. Louis University Hospital in Missouri, where she served as Chief Resident. Dr. Singh obtained board certification in Internal Medicine, Cardiovascular Diseases, and Adult Echocardiography, and has earned the coveted title of Fellow of the American College of Cardiology. She is a member of the National leadership council for Women in Cardiology. She is a board member of the St Louis Metro American Heart Association. Dr. Singh attributes her success to her hard work and dedication, and when she is not working, she enjoys reading and traveling. Learn more about Dr. Singh here: http://www.slhv.com and by reading her upcoming publication in The Leading Physicians of the World. FindaTopDoc.com is a hub for all things medicine, featuring detailed descriptions of medical professionals across all areas of expertise, and information on thousands of healthcare topics. Each month, millions of patients use FindaTopDoc to find a doctor nearby and instantly book an appointment online or create a review. FindaTopDoc.com features each doctor’s full professional biography highlighting their achievements, experience, patient reviews and areas of expertise. A leading provider of valuable health information that helps empower patient and doctor alike, FindaTopDoc enables readers to live a happier and healthier life. For more information about FindaTopDoc, visit http://www.findatopdoc.com
University of Delhi and The Mclean Hospital Corporation | Date: 2017-01-12
Described herein are aminoquinoline and aminoacridine based hybrids, pharmaceutical compositions and medicaments that include such aminoquinoline and aminoacridine based hybrids, and methods of using such compounds for diagnosing and/or treating infections, neurodegenerative diseases or disorders, inflammation, inflammation associated diseases and disorders, and/or diseases or disorders that are treatable with dopamine agonists such as the restless leg syndrome.
Pratap R.,University of Delhi |
Ram V.J.,University of Lucknow
Chemical Reviews | Year: 2014
A study focuses on providing information about the natural products of chromene, furochromenes, pyranochromenes, and benzochromene ring systems, along with the synthesis of various aromatized and partially reduced chromenes, benzo-, and naphtho-fused chromenes, thiochromenopyrans, and their applications in synthetic organic chemistry for the construction of numerous diverse compounds. It is demonstrated that the presence of nitro group at C-5 in XVIIa,b affects the chemical shifts of H-4 and H-6 protons, and they resonate downfield as compared to respective protons of XVIIc due to the presence of electron-withdrawing substituents. It has also been observed that various substituted 2H-chromenes isolated from the leaves of Orthosiphom aristatus have been used as traditional medicine for the treatment of hypertension and diabetes.
Kamei R.G.,University of Delhi
Proceedings. Biological sciences / The Royal Society | Year: 2012
The limbless, primarily soil-dwelling and tropical caecilian amphibians (Gymnophiona) comprise the least known order of tetrapods. On the basis of unprecedented extensive fieldwork, we report the discovery of a previously overlooked, ancient lineage and radiation of caecilians from threatened habitats in the underexplored states of northeast India. Molecular phylogenetic analyses of mitogenomic and nuclear DNA sequences, and comparative cranial anatomy indicate an unexpected sister-group relationship with the exclusively African family Herpelidae. Relaxed molecular clock analyses indicate that these lineages diverged in the Early Cretaceous, about 140 Ma. The discovery adds a major branch to the amphibian tree of life and sheds light on both the evolution and biogeography of caecilians and the biotic history of northeast India-an area generally interpreted as a gateway between biodiversity hotspots rather than a distinct biogeographic unit with its own ancient endemics. Because of its distinctive morphology, inferred age and phylogenetic relationships, we recognize the newly discovered caecilian radiation as a new family of modern amphibians.
Jain A.K.,University of Delhi
Journal of Bone and Joint Surgery - Series B | Year: 2010
The dismal outcome of tuberculosis of the spine in the pre-antibiotic era has improved significantly because of the use of potent antitubercular drugs, modern diagnostic aids and advances in surgical management. MRI allows the diagnosis of a tuberculous lesion, with a sensitivity of 100% and specificity of 88%, well before deformity develops. Neurological deficit and deformity are the worst complications of spinal tuberculosis. Patients treated conservatively show an increase in deformity of about 15°. In children, a kyphosis continues to increase with growth even after the lesion has healed. Tuberculosis of the spine is a medical disease which is not primarily treated surgically, but operation is required to prevent and treat the complications. Panvertebral lesions, therapeutically refractory disease, severe kyphosis, a developing neurological deficit, lack of improvement or deterioration are indications for surgery. Patients who present with a kyphosis of 60° or more, or one which is likely to progress, require anterior decompression, posterior shortening, posterior instrumented stabilisation and anterior and posterior bone grafting in the active stage of the disease. Late-onset paraplegia is best prevented rather than treated. The awareness and suspicion of an atypical presentation of spinal tuberculosis should be high in order to obtain a good outcome. Therapeutically refractory cases of tuberculosis of the spine are increasing in association with the presence of HIV and multidrug-resistant tuberculosis. ©2010 British Editorial Society of Bone and Joint Surgery.
Kalia V.C.,University of Delhi
Biotechnology Advances | Year: 2013
Excessive and indiscriminate use of antibiotics to treat bacterial infections has lead to the emergence of multiple drug resistant strains. Most infectious diseases are caused by bacteria which proliferate within quorum sensing (QS) mediated biofilms. Efforts to disrupt biofilms have enabled the identification of bioactive molecules produced by prokaryotes and eukaryotes. These molecules act primarily by quenching the QS system. The phenomenon is also termed as quorum quenching (QQ). In addition, synthetic compounds have also been found to be effective in QQ. This review focuses primarily on natural and synthetic quorum sensing inhibitors (QSIs) with the potential for treating bacterial infections. It has been opined that the most versatile prokaryotes to produce QSI are likely to be those, which are generally regarded as safe. Among the eukaryotes, certain legumes and traditional medicinal plants are likely to act as QSIs. Such findings are likely to lead to efficient treatments with much lower doses of drugs especially antibiotics than required at present. © 2012 Elsevier Inc.
Kumar G.,University of Delhi |
Gupta R.,University of Delhi
Chemical Society Reviews | Year: 2013
Designed materials offer noteworthy applications which are often architecture dependent. Despite knowing such a fact, one of the major challenges faced by the scientific community is to find ways to predict and, if possible, control the resultant architecture of a network. If such an exercise is fruitful, it creates enormous opportunities to synthesize exotic materials with tailor-made applications. Any network is composed of individual molecules and the transition from a single molecule to a network can be achieved through several routes taking advantage of synthetic chemistry. There exists a molecular building block at the heart of such a transition which mediates such a process from a single molecule to a network. Although a large number of building blocks have created assorted materials, utilization of a well-defined coordination complex as the building block (i.e., metalloligand) is unique for the construction of a designed architecture. A coordination complex as the building block offers structural rigidity that places the auxiliary functional groups to a pre-organized conformation. Such auxiliary functional groups could then coordinate a secondary metal ion or be involved in the self-assembly via weak interactions, such as hydrogen bonds. This review focuses on the recent progress achieved through assorted molecular building blocks towards generating ordered networks. Broadly, two classes of metalloligands will be discussed: those offering hydrogen bond sensitive functional groups and those tendering coordination bond responsive groups. Nevertheless, the result is the construction of networks of a highly-ordered nature in both cases. The present review is expected to provide new strategies for constructing functional materials through metalloligands for challenging and practical applications. © 2013 The Royal Society of Chemistry.
Kumar A.,University of Delhi |
Venkatesu P.,University of Delhi
Chemical Reviews | Year: 2012
An overview of the stability of α-Chymotrypsin (CT) in different solvent media is studied. The degree of stabilization of CT depends on the type of the solvent and the additive and is related to the form of the enzyme (soluble or immobilized) existing in the system. Organic solvents influenced the 3D structure of the CT thereby affecting the stability of the enzyme. If the enzyme exists in immobilized form, its stability depends also on the nature of the support. Protein functional groups in aqueous solution are surrounded by a hydration shell, which is composed of water molecules attached to the protein surface. Solvent hydrophobicity and polarity indirectly influence enzyme activity by affecting the hydration level of the enzyme. It is possible that the ILs reinforce CT structure such that it is able to perform its function more readily, which would account for the most effective stabilizing agents. However, ILs differ in the length of the alkyl group attached to the imidazolium cation, thus presumably differing in their hydrophobicity and ability to interact with the enzyme.
Gopalaiah K.,University of Delhi
Chemical Reviews | Year: 2013
Asymmetric metal-catalytic reactions can produce large quantities of chiral products with a very high efficiency using small amounts of chiral metal catalysts. Much of the work in asymmetric metal catalysis has been performed using noble metals based on rhodium, palladium, ruthenium, and iridium complexes. The next phase of development is the application of iron catalysis in asymmetric synthesis. There are significant developments in the design and use of chiral iron catalysts beginning with Groves discovery of catalytic asymmetric epoxidations with chiral iron-porphyrins in 1983. Cytochromes are redox enzymes, distributed widely in all living cells. They are conjugated proteins having an iron-porphyrin as prosthetic group. Cytochrome c and cytochrome P-450 are the most extensively studied oxidases. They bring about a wide range of stereoselective transformations, such as epoxidations, hydroxylations and others.