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Cincinnati, OH, United States

The University of Cincinnati is a comprehensive public research university in Cincinnati, in the U.S. state of Ohio, and a part of the University System of Ohio.Founded in 1819 as Cincinnati College, it is the oldest institution of higher education in Cincinnati and has an annual enrollment of over 40,000 students, making it the second largest university in Ohio and one of the 50 largest universities in the United States. In the 2010 survey by Times Higher Education , the university was ranked in the top 100 universities in North America and as one of the top 200 in the world. Beginning with the 2011 edition of US News and World Report Best Colleges rankings, the University of Cincinnati has been ranked as a Tier One university, ranking as the 129th best overall university and 63rd best public university in the 2015 rankings. This includes being the number 3 ranked university in the nation in the "Up-and-Coming" National Universities section of the 2014 edition. In 2011-2012 academic year the Leiden University ranking put the University of Cincinnati at the 93rd place globally and at the 63rd place in North America by the proportion of top-cited publications. In 2014, US News and World Report ranked UC in the Top-200 of universities worldwide.The university garners nearly $500 million per annum in research funding, ranking 22nd among public universities in the US. Numerous programs across the university are nationally ranked, including: aerospace engineering, anthropology, architecture, classics, composition, conducting, cooperative education, criminal justice, design, environmental science, law, medicine, music, musical theater, neurology, opera, otolaryngology, paleontology, pediatrics, and pharmacy.The school offers over 100 bachelor degrees, over 300 degree granting programs, and over 600 total programs of study, ranging from certificates to doctoral and first professional education. With an economic impact of over $3.5 billion per year, it is the largest single employer in Greater Cincinnati. After extensive renovations through the implementation of the 1989 Master Plan, the university has been recognized by campus planners and architects as one of the most distinguished campus settings in the world. Wikipedia.


A pharmaceutical composition containing (1) a therapeutically effective amount of hepatocyte-derived exosomes; and (2) a pharmaceutically-acceptable carrier is provided. Also provided herein is a method of inducing liver regeneration in a patient in need thereof, the method including administering to the patient a therapeutic amount of hepatocyte-derived exosomes, wherein liver regeneration is induced. Methods for up-regulating synthesis of synthesis of sphingosine-1-phosphate (S1P) in a hepatocyte by contacting the hepatocyte with at least one vesicle containing sphingosine kinase 2, and, optionally, ceramide and neutral ceramidase, are also disclosed.


Patent
University of Cincinnati | Date: 2015-04-02

A method for manufacturing an electrofluidic device comprising the steps of providing a first plate with features for holding a first fluid, filling a first fluid into features on a first plate; providing a second plate and sealing a second plate onto the first plate forming stacked plates with at least one cavity between the plates, and leaving at least one fill port for a second fluid. Thereafter, the stacked plates are cooled to increase the viscosity of the first fluid so that the first fluid maintains a fixed position as a second fluid is filled into the cavity. Methods are disclosed.


Patent
University of Cincinnati | Date: 2015-04-02

A method for manufacturing a freestanding film having at least one population of through holes cumulatively totaling at least 1% of the film area, wherein the standard deviation of hole diameters is less than 25% and a thickness less than 25 micrometers, The film provides a carrier substrate, a photo-curable material, a release agent and deposits a photo-curable material on the substrate, selectively curing the material and leaving uncured material in the pattern of holes, dissolving away the uncured material and removing the cured material from the carrier. Methods and apparatus are described.


Patent
Procter, Gamble and University of Cincinnati | Date: 2015-03-23

The homogeneous hydrogenation of organic carbonyls, especially esters, under relatively mild conditions using iron hydrido-borohydride catalyst complexes having amino-phosphine pincer ligands. The catalyst and process are well-suited for catalyzing the hydrogenation of a wide variety of organic carbonyls, such as hydrogenation of fatty acid esters to alcohols. In particular embodiments, the process can be carried out in the absence of solvent.


Patent
University of Cincinnati | Date: 2015-04-23

Describe are methods of extracting the lipid fraction from trap grease using vegetable oil, such as vegetable oils sourced from waste cooking oil. The method includes mixing a volume of vegetable oil with a volume of trap grease. The mixture is comprised of an aqueous fraction, a solid fraction, and a lipid fraction. The mixture is heated to a temperature in a range from about 50 degrees C. to about 100 degrees C. for a period of time sufficient to extract at least 80 percent of the lipids from the trap grease. The lipid fraction is then separated from the solid fraction. The method may further include a process of producing biodiesel from the extracted lipid fraction.

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