Cincinnati, OH, United States

University of Cincinnati

www.uc.edu
Cincinnati, OH, United States

The University of Cincinnati is a comprehensive public research university in Cincinnati, in the U.S. state of Ohio, and a part of the University System of Ohio.Founded in 1819 as Cincinnati College, it is the oldest institution of higher education in Cincinnati and has an annual enrollment of over 40,000 students, making it the second largest university in Ohio and one of the 50 largest universities in the United States. In the 2010 survey by Times Higher Education , the university was ranked in the top 100 universities in North America and as one of the top 200 in the world. Beginning with the 2011 edition of US News and World Report Best Colleges rankings, the University of Cincinnati has been ranked as a Tier One university, ranking as the 129th best overall university and 63rd best public university in the 2015 rankings. This includes being the number 3 ranked university in the nation in the "Up-and-Coming" National Universities section of the 2014 edition. In 2011-2012 academic year the Leiden University ranking put the University of Cincinnati at the 93rd place globally and at the 63rd place in North America by the proportion of top-cited publications. In 2014, US News and World Report ranked UC in the Top-200 of universities worldwide.The university garners nearly $500 million per annum in research funding, ranking 22nd among public universities in the US. Numerous programs across the university are nationally ranked, including: aerospace engineering, anthropology, architecture, classics, composition, conducting, cooperative education, criminal justice, design, environmental science, law, medicine, music, musical theater, neurology, opera, otolaryngology, paleontology, pediatrics, and pharmacy.The school offers over 100 bachelor degrees, over 300 degree granting programs, and over 600 total programs of study, ranging from certificates to doctoral and first professional education. With an economic impact of over $3.5 billion per year, it is the largest single employer in Greater Cincinnati. After extensive renovations through the implementation of the 1989 Master Plan, the university has been recognized by campus planners and architects as one of the most distinguished campus settings in the world. Wikipedia.

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Patent
University of Cincinnati | Date: 2017-08-02

A sweat sensor device (200) with analytical assurance includes at least one sensor (220) for detecting a first analyte, and at least one calibration medium (270) containing at least the first analyte. When the first analyte in the at least one calibration medium (270) comes into contact with the at least one sensor (220), the calibration medium (270) provides a calibration of the at least one sensor (220). A sweat sensor device (200) may further include a carrier (240) having at least one aperture (220a) and a reservoir (254) for storing the at least one calibration medium (270). The at least one aperture (220a) provides fluidic access to the at least one sensor (220) from the reservoir (254).


Patent
University of Cincinnati | Date: 2017-02-28

A method for manufacturing an electrofluidic device comprising the steps of providing a first plate with features for holding a first fluid, filling a first fluid into features on a first plate; providing a second plate and sealing a second plate onto the first plate forming stacked plates with at least one cavity between the plates, and leaving at least one fill port for a second fluid. Thereafter, the stacked plates are cooled to increase the viscosity of the first fluid so that the first fluid maintains a fixed position as a second fluid is filled into the cavity. Methods are disclosed.


Patent
University of Cincinnati and U.S. Air force | Date: 2017-05-17

A wearable sweat sensor device (1) may include a plurality of sensors (150, 160, 170, 180) capable of measuring a plurality of ion-selective biomarker potentials and a mechanism that analyzes a combination of measurements as a proxy for one or more physiological conditions such as muscle activity, exertion, or tissue damage. A device may include a sensor capable of taking at least one skin impedance measurement along with a plurality of sensors (150, 160, 170, 180) and a mechanism that analyzes a combination of measurements as a proxy for one or more physiological conditions, such as hydration or sweat rate. Because several of said sensors (150, 160, 170, 180) may not be stable when stored if fully exposed to air, the device (1) may include a temporary seal (400) for said sensors (150, 160, 170, 180) that is removable prior to placement and use of said sensors (150, 160, 170, 180).


Patent
University of Cincinnati | Date: 2017-04-05

A sweat sensor device (400c) for sensing sweat on the skin (12) includes one or more sweat sensors (420) and a volume-reducing component that provides a volume-reduced pathway (480) for sweat between the one or more sweat sensors (420) and sweat glands in said skin (12) when the device (400c) is positioned on said skin (12). The volume-reducing component may include a volume -reducing material (470) and a pressure-permeated component (460), a sweat dissolvable material (490), a mechanically compliant material (570) for conforming to the skin (12), an adhesive with a vertically anisotropic sweat pathway, and microcapsules (1385) including a barrier material. The presence of a volume-reducing component reduces the sweat volume and decreases the sampling interval.


Patent
University of Cincinnati | Date: 2017-04-05

The concentration of an administered compound, such as a drug (D), in an organ or a bodily fluid, such as blood, is determined directly through detecting the drug (D) or its metabolites (DM) in sweat. The concentration may be determined indirectly by administering the drug (D) together with one or more tracer compounds (T, T2) or metabolites thereof (TM, T2M) or by detecting concentrations and trends of other analytes present in the body that react to the presence of the drug (D). By determining tracer concentration in sweat, the concentration of the drug (D) in blood or an organ can be determined. The tracer (T, T2) is a compound selected for ease of detection in sweat, known metabolic and solubility profiles that correspond to those of the drug (D), and safety of use. A smart transdermal delivery patch (300) is used to administer a dosage of drug to a wearer in coordination with at least one sweat sensor (324) reading conveying information about the wearer.


Patent
University of Cincinnati | Date: 2017-04-05

An electronic sweat sensor (300) includes a plurality of porous substrates (310, 312), each porous substrate (310, 312) having an electrically conductive surface (320, 322). The porous substrates (310, 312) have a generally planar surface. The generally planar surface may be adapted to be positioned on skin (12) generally coplanar with the skin. The electronic sweat sensor (300) further includes a porous spacer (315) layer defining a gap between at least two of the porous substrates (310, 312). When an analyte flow (305), which may be from skin (12), is moving perpendicular to the planar surface and through at least one of the porous substrates (310, 312), at least one of the conductive surfaces (320, 322) provides an electrical response to the presence of the analyte flow (305).


Patent
University of Cincinnati | Date: 2017-01-20

The present disclosure relates to the use of pharmaceutical agents to manipulate serotonin in animal mammary glands. Use of the serotonin agents results in increased PTHrP levels, resulting in the release of calcium from the bone, which improves lactation.


A sweat sensing device (28) includes a plurality of sweat collection pads (40, 42, and 44) communicating with a sensor (36). Each of the pads (40, 42, and 44) is activated by electronics (34) that include a timing circuit which allows one or more of the pads (40, 42, and 44) to be activated at a selected time and subsequent deactivated after a defined period of time. This allows for selective collection of sweat from a plurality of pads over a prolonged period of time. Further, the devices can use a common microfluidic device (38) which both transports sweat activating substance, such as pilocarpine, to the surface of the skin (12) and directs sweat away from the skin (12) to a sensing device (28).


Patent
Procter, Gamble and University of Cincinnati | Date: 2017-02-08

The homogeneous hydrogenation of organic carbonyls, especially esters, under relatively mild conditions using iron hydrido-borohydride catalyst complexes having amino-phosphine pincer ligands. The catalyst and process are well-suited for catalyzing the hydrogenation of a wide variety of organic carbonyls, such as hydrogenation of fatty acid esters to alcohols. In particular embodiments, the process can be carried out in the absence of solvent.


Patent
University of Cincinnati | Date: 2017-04-05

A sweat sensor device (200) includes one or more sweat sensors (220) and a seal (280) covering the one or more sweat sensors (220). The seal (280) is adapted to protect the sweat sensors (220) from outside contaminants when the device (200) is placed on the skin (12). The sweat sensor device (200) may include an absorbing medium (230) to absorb sweat from the skin (12) that is covered by the seal (280). The seal (280) can be permeable to gas, permeable to water and impermeable to at least one aqueous solute, or selectively permeable to at least one aqueous solute. The sweat sensor device (200) may include an artificial sweat stimulation mechanism (345) for stimulating sweat when the device (200) is placed on the skin (12).

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