Castillo-Cadena J.,University of Central Mexico |
Mejia-Sanchez F.,University of Central Mexico |
Lopez-Arriaga J.A.,University of Central Mexico
Environmental Science and Pollution Research | Year: 2017
Birth defects are the number one cause of child mortality worldwide and in 2010 it was the second cause in Mexico. Congenital malformations are a public health issue, because they cause infant mortality, chronic disease and disability. The origin can be genetic, environmental or unknown causes. Among environmental contaminants, pesticides stand out. In this study, we determine the frequency and etiology of congenital malformations in newborns (NBs) of a floricultural community and we compare it with that in the urban community. For 18 months, the NBs were monitored at the Tenancingo General Hospital and the Mother and Child Gynecology and Obstetrics Hospital (IMIEM) in Toluca. The identification of these malformations was carried out in accordance with the WHO. In Tenancingo, 1149 NBs were viewed, where 20% had some kind of congenital malformations. While in the IMIEM, 5069 were reviewed and 6% had some malformation. According to the etiology, in Tenancingo, 69% were multifactorial, 28% were monogenetic and 2% were chromosomal. In the IMIEM, 47% were multifactorial, then 18.3% were monogenetic and 2.8% were chromosomal. There was a significant difference between the global frequency of malformations and the multifactorial etiology of both institutions. Our results show that congenital malformations in the NBs occurred more frequently in the floricultural zone and that because the percentage of multifactorial etiology is higher, it is likely there is an association with exposure to pesticides. © 2017 Springer-Verlag Berlin Heidelberg
Bautista-Gomez L.,National Autonomous University of Mexico |
Martinez-Castaneda S.,University of Central Mexico
Mitochondrial DNA Part A: DNA Mapping, Sequencing, and Analysis | Year: 2017
Canine transmissible venereal tumour (CTVT) has been transmitted by cell transplantation from dog to dog, for over 10 000 years. Although initial studies report a single genetic origin for CTVT, recent samples from around the world reveal high genetic diversity. An elevated number of polymorphisms have been determined in mitochondrial DNA (mtDNA) of CTVT. The recent discovery of mtDNA transference from the host into tumoural cells could be a novel source of genetic diversity in CTVT. The aim of this study was to determine the presence of host mtDNA in samples of CTVT in Mexican dogs. Genotyping of 49 samples of CTVT and 49 samples of blood cells pertaining to affected dogs was performed by direct sequencing from the mtDNA D-loop region. Exogenous mtDNA was observed in 6% of the analysed tumours. This is the first investigation reporting the prevalence of exogenous mtDNA in CTVT in the Mexican dog population. © 2016 Informa UK Limited, trading as Taylor & Francis Group.
Salgado-Miranda C.,University of Central Mexico |
Loza-Rubio E.,National Institute for Forestry |
Rojas-Anaya E.,National Institute for Forestry |
Garcia-Espinosa G.,National Autonomous University of Mexico
Expert Review of Vaccines | Year: 2013
Since 1970, aquaculture production has grown. In 2010, it had an annual average rate of 6.3% with 59.9 million tons of product and soon could exceed capture fisheries as a source of fishery products. However, the occurrence of viral diseases continues to be a significant limiting factor and its control is important for the development of this sector. In aquaculture farms, fish are reared under intensive culture conditions, and the use of viral vaccines has enabled an increase in production. Several types of vaccines and strategies of vaccination have been developed; however, this approach has not reached the expected goals in the most susceptible stage (fingerlings). Currently, there are inactivated and recombinant commercial vaccines, mainly for salmonids and cyprinids. In addition, updated genomic and proteomic technology has expedited the research and expansion of new vaccine models, such as those comprised of subunits or DNA. The objective of this review is to cover the various types of viral vaccines that have been developed and are available for bony fishes, as well as the advantages and challenges that DNA vaccines present for massive administration in a growing aquaculture, possible risks for the environment, the controversy regarding genetically modified organisms and possible acceptance by consumers. © 2013 2013 Expert Reviews Ltd.
Barile-Fabris L.,Hospital Of Especialidades |
Hernandez-Cabrera M.F.,University of Central Mexico |
Barragan-Garfias J.A.,Hospital General Regional 48
Current Rheumatology Reports | Year: 2014
Systemic lupus erythematosus (SLE) is a complex heterogeneous autoimmune disease with a wide variety of clinical and serological manifestations that may affect any organ. Vasculitis prevalence in SLE is reported to be between 11% and 36%. A diverse clinical spectrum, due to inflammatory involvement of vessels of all sizes, is present. Even though cutaneous lesions, representing small vessel involvement, are the most frequent, medium and large vessel vasculitis may present with visceral affection, with life-threatening manifestations such as mesenteric vasculitis, pulmonary hemorrhage, or mononeuritis multiplex, with detrimental consequences. Early recognition and an appropriate treatment are crucial. Recent studies have shown that vasculitis in patients with SLE may present different clinical forms based on the organ involved and the size of the affected vessel. It is noteworthy that the episodes of vasculitis are not always accompanied by high disease activity. Recent articles on this topic have focused on new treatments for the control of vascular disease, such as biological therapies such as Rituximab and Belimumab, among others. © Springer Science+Business Media 2014.
Feria-Ortiz M.,University of the East of Mexico |
Manrquez-Morn N.L.,University of Central Mexico |
De Oca A.N.-M.,National University of Costa Rica
Herpetological Monographs | Year: 2011
The Mexican Plestiodon brevirostris species group (Squamata: Scincidae) is composed of seven nominal species. The wide-ranging P. brevirostris is a polytypic species composed of five subspecies: P. b. brevirostris, P. b. bilineatus, P. b. dicei, P. b. indubitus, and P. b. pineus. A tree-based approach for species delimitation with mtDNA data was used to test the traditional species-level taxonomy of P. brevirostris preliminarily. A haplotype phylogeny for all of the species and subspecies in the P. brevirostris group, except P. colimensis, was inferred. The mtDNA data consisted of sequences encompassing the genes encoding 16S rRNA (part), ND1, and associated tRNAs (1355 base pairs), which were analyzed with Bayesian methods. Then, a search for diagnostic morphological characters for the putative species delimited by this approach was performed. The results indicate that the P. brevirostris group is paraphyletic with respect to P. lynxe, and that P. brevirostris actually is composed of at least five distinct lineages disguised by traditional taxonomy: P. b. brevirostris, P. b. bilineatus, P. b. dicei, and the eastern populations of P. b indubitus (from Morelos, Guerrero, and México) represent distinct species, whereas the western populations of P. b. indubitus (from Colima and Jalisco) represent an undescribed species. The data cannot resolve whether P. b. pineus is conspecific with P. b. dicei or P. b. dicei is a paraphyletic (?=?nonexclusive) species relative to an exclusive P. b. pineus. Thus, the status of P. b. pineus remains uncertain. The haplotype phylogeny also suggests that P. b. brevirostris may represent more than one species. © 2011 The Herpetologists' League, Inc.
Alanis C.,National Autonomous University of Mexico |
Natividad R.,National Autonomous University of Mexico |
Barrera-Diaz C.,National Autonomous University of Mexico |
Martinez-Miranda V.,University of Central Mexico |
And 2 more authors.
Applied Catalysis B: Environmental | Year: 2013
This work aims to present a study of the adsorption and photocatalytic reduction of Cr(VI) by ZnAl, MgZnAl and MgAl mixed oxides derived from layered double hydroxides (LDHs). The effect of variables like Zn content and pH (3 and 6.5) on Cr(VI) removal efficiency is presented. The catalysts were characterized by X-ray diffraction (XRD) and infrared spectroscopy (FTIR). The reaction progress was verified by UV/vis spectrophotometry with a colorimetric method. A maximum of 99.5% Cr(VI) was photocatalytically removed and this process was approximately two times faster than adsorption. In addition, it was found that the use of these materials does not imply the addition of further chemicals to regulate pH since the free basic pH of the catalyst-contaminant suspension positively affects both adsorption and photo-reduction kinetics. © 2013 Elsevier B.V.
Gonzalez P.G.,University of Central Mexico |
Pliego-Cuervo Y.B.,IT de Orizaba
Chemical Engineering Research and Design | Year: 2014
Mesoporous activated carbon (surface area of 608 m2/g) has achieved high efficiency in removal of cadmium, mercury and zinc ions from water solution. The proposed low-cost adsorbent was physically activated with water steam from the bamboo species Bambusa vulgaris striata. The batch studies suggested an activated carbon dose of 0.6g/L, solution pH of 9 and an equilibrium time of 16h in static conditions. The pseudo-second order equations represented the adsorption kinetics with high correlation. Fitting of the experimental results to the Langmuir, Freundlich, Redlich-Peterson and Toth isotherm models showed an almost homogeneous surface coverage and presence of physical adsorption. The highest adsorption capacities, calculated from the Langmuir model, are 239.45, 248.05 and 254.39 mg/g of cadmium, mercury and zinc, respectively. © 2014 The Institution of Chemical Engineers.
Juarez-Aguirre R.,University of Central Mexico
Sensors (Basel, Switzerland) | Year: 2013
We present a signal processing system with virtual instrumentation of a MEMS sensor to detect magnetic flux density for biomedical applications. This system consists of a magnetic field sensor, electronic components implemented on a printed circuit board (PCB), a data acquisition (DAQ) card, and a virtual instrument. It allows the development of a semi-portable prototype with the capacity to filter small electromagnetic interference signals through digital signal processing. The virtual instrument includes an algorithm to implement different configurations of infinite impulse response (IIR) filters. The PCB contains a precision instrumentation amplifier, a demodulator, a low-pass filter (LPF) and a buffer with operational amplifier. The proposed prototype is used for real-time non-invasive monitoring of magnetic flux density in the thoracic cage of rats. The response of the rat respiratory magnetogram displays a similar behavior as the rat electromyogram (EMG).
Pulido-Velazquez M.,Polytechnic University of Valencia |
Alvarez-Mendiola E.,University of Central Mexico |
Andreu J.,Polytechnic University of Valencia
Journal of Water Resources Planning and Management | Year: 2013
By ignoring the opportunity cost of water use, water is undervalued, which can lead to significant errors in investments and water allocation decisions. The marginal resource opportunity cost (MROC) varies in time and space, as resource availability, demands, and users' WTP vary. This spatial and temporal variability can only be captured by basinwide hydro-economic models integrating water demands and environmental requirements, resources, infrastructure, and operational and institutional restrictions. This paper presents a method for the simulation of water pricing policies linked to water availability, and the design of efficient pricing policies that incorporate the basinwide marginal value of water. Two approaches were applied: priority-based simulation and economic optimization. The improvement in economic efficiency was assessed by comparing the results from simulation of the current system operation and the pricing schedule. The difference between the benefits for the simulated current management and the upper bound benefits from optimization indicates the maximum gap that could be bridged with pricing. In the application to a synthetic case, a storage-dependent step pricing schedule derived from average MROC values led to benefits that capture 80% of the gap of net benefits between management without pricing and the economically optimal management. Different pricing policies were tested, depending not only on reservoir storage but also on previous inflows. The results show that the method is useful for designing pricing policies that enhance the economic benefits, leading to more efficient resource allocations over time and across the competing uses. © 2013 American Society of Civil Engineers.
Gil-Rodriguez P.,University of Central Mexico |
Amero C.,University of Central Mexico
Biomolecular NMR Assignments | Year: 2015
Primary amyloidosis (AL) is the most common amyloid systemic disease and it is characterized by the deposition of immunoglobulin light-chain amyloid fibers in different organs, causing organ failure. The germ-line lambda 3 immunoglobulin light-chain proteins have been correlated with the AL condition. Two mutants have been derived from this germ-line, the single mutant C34Y (3rC) and the triple mutant C34Y, W35A and P7D (3rCWP), presenting a remarkable difference in amyloid fibril formation propensities in vitro. Here we report the 1H, 13C and 15N resonance assignments of these proteins, as the first step to use solution nuclear magnetic resonance spectroscopy to get a better understanding of the amyloid fibril formation differences between these two mutants. © 2014, Springer Science+Business Media Dordrecht.