Caxias do Sul, Brazil

University of Caxias do Sul
Caxias do Sul, Brazil

The University of Caxias do Sul is among the largest universities in the Brazilian state of Rio Grande do Sul, by number of students . It was founded in 1967. It is almost completely located in Caxias do Sul, but there are also campi in Bento Gonçalves, Vacaria, Farroupilha, Guaporé, Nova Prata, São Sebastião do Caí, Canela and Veranópolis. Wikipedia.

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SOLON, Ohio--(BUSINESS WIRE)--Multi Radiance Medical’s MR4 super pulsed laser better enhances athletic performance and recovery compared to Class IV lasers, according to a recent study published in the peer-reviewed Journal of Athletic Training. Dr. Thiago De Marchi, et al. from the University of Caxias do Sul's Sports Medicine Institute compared the Multi Radiance Medical super pulsed laser to two other commercially available lasers from Thor Photomedicine and LiteCure in a double-blinded, randomized, placebo-controlled study. The researchers conducted the study to provide a direct product comparison of commercially available laser therapy devices to help clinicians incorporate photobiomodulation into clinical practice. Study participants received phototherapy before a set of leg exercises and were measured on three outcomes: muscle strength, muscle soreness, and biochemical muscle damage up to 96 hours after the exercises. Both low level laser devices outperformed the high powered laser device. “Low-powered pulsed laser/light demonstrated better results than either low-powered continuous laser/light or high-powered continuous laser/light in all outcome measures when compared with placebo,” the authors concluded. The Multi Radiance Medical super pulsed laser performed better than the Class IV lasers on all outcome measures. Participants using the super pulsed laser recovered faster and avoided fatigue, reducing the risk of injury. Despite Class IV manufacturer claims of effectiveness, research on high-powered lasers remains of poor scientific quality due to the inability to mask the excessive heat produced during application – precluding a true double-blinded, placebo-controlled study protocol. “The increase in creatine kinase (CK) activity using the high-powered continuous laser/light compared with placebo warrants further research to investigate its effect on other factors related to muscle damage,” the researchers concluded. Super pulsed lasers emit light in billionth-of-a-second pulses which prevents photon accumulation at the skin’s surface. This creates a high peak power for effectively relieving pain, yet a low average power to eliminate risk of thermal damage. There are over 10 recent peer-reviewed studies published in journals documenting the beneficial ergogenic effects of Multi Radiance super pulsed laser photobiomodulation therapy. Multi Radiance Medical is a global leader in the development and manufacturing of FDA-cleared super pulsed lasers for pain relief, sports performance and accelerated recovery. Their proprietary super pulsed laser technology has been validated and optimized and is the choice of over 80 professional and collegiate sports teams.

Poletto M.,University of Caxias do Sul
Maderas: Ciencia y Tecnologia | Year: 2017

The thermal behavior of lignins from softwood and hardwood species has been investigated using thermogravimetry and differential scanning calorimetry. Klason Lignin from Pinus taeda and Klason lignin from Eucalyptus grandis were studied. The differential scanning calorimetry results showed that both Klason lignins studied presented similar glass transition temperature. Thermogravimetric results showed that the lignin degradation occurs in three stages. The Klason lignin of Pinus taeda is more thermally stable than Eucalyptus grandis, probably because of the higher thermal stability of the guaiacyl units in softwood lignin. The degradation of both lignins initiate by a diffusion process. However when the conversion values are higher than 0,1 the lignin degradation mechanism is a complex procedure and involves the degradation of a highly condensed aromatic structure formed at the previous degradation stages.

Aguirre T.A.S.,University of Caxias do Sul | Teijeiro-Osorio D.,University of Santiago de Compostela | Rosa M.,Dublin City University | Coulter I.S.,Dublin City University | And 2 more authors.
Advanced Drug Delivery Reviews | Year: 2016

The development of oral dosage forms that allows absorption of therapeutic peptides to the systemic circulation is one of the greatest challenges for the pharmaceutical industry. Currently, a number of technologies including either mixtures of penetration enhancers or protease inhibitors and/or nanotechnology-based products are under clinical development. Typically, these formulations are presented in the form of enteric-coated tablets or capsules. Systems undergoing preclinical investigation include further advances in nanotechnology, including intestinal microneedle patches, as well as their combination with regional delivery to the colon. This review critically examines four selected promising oral peptide technologies at preclinical stage and the twelve that have progressed to clinical trials, as indicated in We examined these technologies under the criteria of peptide selection, formulation design, system components and excipients, intestinal mechanism of action, efficacy in man, and safety issues. The conclusion is that most of the technologies in clinical trials are incremental rather than paradigm-shifting and that even the more clinically advanced oral peptide drugs examples of oral bioavailability appear to yield oral bioavailability values of only 1–2% and are, therefore, only currently suitable for a limited range of peptides. © 2016 Elsevier B.V.

Dani C.,University of Caxias do Sul
Genetics and molecular research : GMR | Year: 2012

Grape juices are an important source of food antioxidants. Unfortunately, there is little data about the mineral composition and the antioxidant, mutagenic and antimutagenic activities of grape juice in eukaryote cells. We evaluated the mineral contents (Mg, Ca, Mn, Fe, Cu, Zn, Si, S, Cl) of grape juices, the antioxidant, mutagenic and/or antimutagenic activities of the juices in the yeast Saccharomyces cerevisiae, and looked for a possible association between mineral content and antioxidant, mutagenic and/or antimutagenic activities of juice samples. Eight commercial grape juices, four purple (Bordo variety) and four white (Niagara variety), were evaluated. Most of the minerals were in similar concentrations in purple and white grape juices, except for calcium and copper; purple grapes had more calcium content and white grapes had more copper content. All grape juices had important antioxidant and antimutagenic activities in S. cerevisiae and prevented the oxidative damage provoked by hydrogen peroxide (P < 0.05). Positive correlations (P < 0.05) were observed between antioxidant and antimutagenic activities and mineral content. In this context, we concluded that the grape juices, white and purple, are an important mineral source, and these contents explain, in part, the important antioxidant and antimutagenic activities.

Gava V.,University of Caxias do Sul | Martinotto A.L.,University of Caxias do Sul | Perottoni C.A.,University of Caxias do Sul
Physical Review Letters | Year: 2012

Mode Grüneisen parameters were estimated for α-ZrW 2O 8 zone-center modes by means of density functional theory calculations and the temperature dependence of the coefficient of thermal expansion was obtained according to the Debye-Einstein model of the quasiharmonic approximation. The lowest energy optic modes were identified at 45 and 46cm -1, and were shown to be the main modes responsible for negative thermal expansion at low temperature. Experimental evidence of the lowest energy, triply degenerated infrared active optic mode, was also found in the far infrared spectrum of α-ZrW 2O 8. Upon increasing temperature, other optic modes with E<25meV (particularly at 96, 100, 133, 161, and 164cm -1) also contribute significantly to the coefficient of thermal expansion near room temperature. An analysis was made of selected zone-center modes in light of previously proposed models for explaining negative thermal expansion in open framework materials. © 2012 American Physical Society.

Fontana R.C.,University of Caxias do Sul | da Silveira M.M.,University of Caxias do Sul
Bioresource Technology | Year: 2012

The production of endo- and exo-polygalacturonase (PG) by Aspergillus oryzae was assessed in stirred tank reactors (STRs), internal-loop airlift reactors (ILARs) and external-loop airlift reactors (ELARs). For STR production, we compared culture media formulated with either pectin (WBE) or partially hydrolyzed pectin. The highest enzyme activities were obtained in medium that contained 50% pectin in hydrolyzed form (WBE5). PG production in the three reactor types was compared for WBE5 and low salt WBE medium, with additional salts added at 48, 60 and 72 h (WBES). The ELARs performed better than the ILARs in WBES medium where the exo-PG was the same concentration as for STRs and the endo-PG was 20% lower. These results indicate that PG production is higher under experimental conditions that result in higher cell growth with minimum pH values less than 3.0. © 2012 Elsevier Ltd.

Zambra D.A.B.,University of Caxias do Sul | Rech C.,Federal University of Santa Maria | Pinheiro J.R.,Federal University of Santa Maria
IEEE Transactions on Industrial Electronics | Year: 2010

This paper presents a comparison of three topologies of multilevel inverters applied to drive an induction motor of 500 kVA/4.16 kV rating. The multilevel inverters analyzed are the following: a neutral-point-clamped inverter, a symmetrical cascaded multilevel inverter, and a hybrid asymmetrical cascaded multilevel inverter. The performance indexes used in the comparison are total harmonic distortion, first-order distortion factor, second-order distortion factor, common-mode voltage, semiconductor power loss distribution, and heat-sink volume. The multilevel inverters are designed to present 99% efficiency at the nominal operating point, and the aforementioned performance indexes are compared for distinct values of amplitude modulation depth. © 2010 IEEE.

Campos R.A.,University of Caxias do Sul
Genetics and molecular research : GMR | Year: 2010

Pathogenicity of strains of the entomopathogenic fungus Beauveria bassiana and endophytic strains of Beauveria sp against the bovine tick Rhipicephalus (Boophilus) microplus was tested in laboratory bioassays and under field conditions. Suspensions containing 10(5), 10(7) and 10(9) conidia/mL were prepared of each fungal strain for laboratory bioassays. The ticks were maintained at 28 degrees C, 90 +/- 5% relative humidity, and the following variables were evaluated: initial female weight, egg weight, hatching percentage, reproductive efficiency, and percentage control. For tests under field conditions, a Beauveria suspension containing 10(6) conidia/mL was sprayed on tick-infested cows. After 72 h, the ticks were collected to estimate mortality under field conditions. Laboratory bioassays showed a mortality of 20 to 50% of the ticks seven days after inoculation with 10(7) Beauveria conidia/mL. Under field conditions 10(6) Beauveria conidia/mL induced 18-32% mortality. All Beauveria strains were effective in biological control of R. (Boophilus) microplus under laboratory and field test conditions. This is the first demonstration that endophytic fungi can be used for biological control of the cattle tick; this could help reduce environmental contamination by diminishing the need for chemical acaricides. Two endophytic strains were isolated from maize leaves and characterized by molecular sequencing of 5.8S rDNA ITS1 and ITS2 and morphological analyses of conidia. We found that these two endophytic Beauveria isolates, designated B95 and B157, are close to Beauveria amorpha.

A method, a system and an apparatus for predicting and/or recognizing and/or classifying biological sequences, specially sequence families with binding site recognition motifs poorly conserved, comprising, advantageously, the use of neural networks rules; providing enhanced and more accurate results; and is preferably used when the biological sequence is a promoter.

Agency: GTR | Branch: ESRC | Program: | Phase: Research Grant | Award Amount: 24.35K | Year: 2015

Brazils current social and political situation gives rise to a particular breed of urban violence aimed at individuals and characterized by its continual presence. The average Brazilian citizen has to contend with this violence on a daily basis. This creates a general state of fear and insecurity among the population in general, but, at the same time, may promote on the part of more socially aware individuals, a sense of empathy with the less privileged classes in Brazil. The influence of the media contributes to this scenario. Daily news reports highlight violent acts carried out by individuals or groups from all social classes. The impact of violence on peoples everyday lives is thus amplified by the media. This fosters beliefs, attitudes and values related to violence, which may or may not be consistent with the actual incidence, forms and causes of violence. The partners will investigate the linguistic representation of urban violence in Brazil by applying the techniques of Corpus Linguistics to two datasets, or corpora: 1. The existing transcripts of two focus groups on living with urban violence conducted in Fortaleza, Brazil in 2010, for a total of approximately 20,000 words (Focus Groups Corpus); 2. A 2-million-word corpus of news reports in the Brazilian press, to be constructed as part of the partnership (News Reports Corpus).

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