Agency: Cordis | Branch: H2020 | Program: MSCA-RISE | Phase: MSCA-RISE-2015 | Award Amount: 706.50K | Year: 2016
NanoMaterials safety is of great societal concern and raises many questions for the general public, governments, industry, scientists and regulators. Identifying and controlling the hazards associated with NMs is required to ensure the safety in parallel to exploiting the technological benefits. NANOGENTOOLS answers this challenge by creating a collaborative excellence-based knowledge exchange network that will: i) push forward knowledge via method development and pre-validation, ii) train scientists in new methodologies to assess long term nanosafety, and iii) support their inclusion in standardization and EU regulations. NANOGENTOOLS combines toxicogenomics, proteomics, biophysics, molecular modeling, chemistry, bio/chemoinformatics to develop fast in vitro high throughput (HTS) assays, with molecular based computational models for nanotoxicity. Its objectives are to: Provide solutions for faster, more reliable assessment of NM toxicity and propose HTS and omics tools for predicting toxicological properties of NMs. Develop new bioinformatics methodologies for analyzing -omics data and create an open database in collaboration with the EU Nanosafety Cluster. Conduct research and training on biophysical techniques and mathematical models for accurate and fast nanotoxicity prediction. Build/improve the safe by design concept, demonstrated using carbon-NMs and nanosensors. Place our new knowledge in the context of regulations and EU roadmaps. NANOGENTOOLS brings together cutting edge research, innovative knowledge-transfer and co-development, and cross-sectoral and cross-disciplinary secondments linking EU academic institutes/networks with industry and policy makers across 8 countries. Expected impacts include pre-validated tools for efficient cost-effective nanosafety assessment applicable to SMEs for incorporation into regulatory frameworks, and translation of knowledge via development of a CNT-based nanosensor based on safe-by-design principles.
Agency: Cordis | Branch: H2020 | Program: RIA | Phase: NMP-23-2015 | Award Amount: 7.15M | Year: 2016
The demand for lower dependency on critical raw materials (CRM) such as rare earths (RE) is not only a European but a global problem that demands immediate action. The purpose of this project is to exploit advanced theoretical and computation methods together with state-of-the-art materials preparation and characterization techniques, to develop the next generation RE-free/lean permanent magnets (PM). The material design will be driven by automated large computational screening of new and novel intermetallic compounds with uniaxial structure in order to achieve high saturation magnetisation, magnetocrystalline anisotropy and Curie temperature. The simulations will be based on a primary screening detecting the mechanisms that give rise to distorted phases and stabilize them, by adding doping atoms as stabilizers. In a further computation on successfully synthetized compounds, micromagnetic calculations will be used in order to design the optimal microstructure for the given phases that will maximise the coercivity needed for a PM. Extensive experimental processing and characterisation of the selected phases will result in a first proof of principle of the feasibility of NOVAMAG PMs. A multidisciplinary team of magnet experts consisting of chemists, material scientists, physicists and engineers from academia, national labs and industry is assembled to undertake a concerted, systematic and innovative study to overcome the problems involved and develop the next generation RE-free/lean PMs. Currently the demand for these PM s is even higher with the emerging markets of hybrid/electric vehicles and wind mill power systems. The proposed project will provide the fundamental innovations and breakthroughs which will have a major impact in re-establishing the Europe as a leader in the science, technology and commercialization of this very important class of materials and help decrease our dependence on China, which will in turn improve the competitiveness of EU manufacturers.
Agency: Cordis | Branch: H2020 | Program: RIA | Phase: FETOPEN-1-2014 | Award Amount: 2.70M | Year: 2016
ICARUS proposes a new thermodynamic methodology able to identify the elements and the relative chemical composition allowing a nanocrystalline state to occupy a relative minimum of the Gibbs free energy, which makes the nanostructure reasonably stable against coarsening. This approach will be integrated, in synergy with multiscale and thermodynamic (Nano-Calphad) modeling, in order to implement a High-Throughput Screening (HTS) tool that will open a new horizon of discovery and exploration of multinary thermal stable nanocrystalline alloys, exhibiting superb tailored properties. ICARUS brings a radically new concept by addressing a still unsolved problem in the stabilization of nanocrystalline alloys. The materials discovery approach of ICARUS will be synergistic with the forefront industrial production technologies of nanomaterials and alloys. Results arising from ICARUS exploration will be materialized in specific demo compounds representative of carefully selected new alloys families that will change the present paradigm of EU aerospace industry. The most promising nanocrystallyne material identified will be synthesized by mechanical alloying and physical vapor deposition, and the obtained samples characterized toward the applicability in the aerospace sector. A proof of concept from its approach will be given and tested by experts and specialized industries working in the aerospace sector in close contact with NASA and ESA. In particular, ICARUS will demonstrate its potential by producing innovative coarsening-resistant nanocrystalline alloys with enhanced radiation tolerance (based on refractory metals), and light-weight high strength (based on Al, Mg, Ti) alloys.
Agency: Cordis | Branch: H2020 | Program: CSA | Phase: SC5-15-2016-2017 | Award Amount: 3.00M | Year: 2016
Since the publication of the first list of Critical Raw Materials (CRM) in 2010 by the Ad-hoc Working Group on CRM, numerous European projects have addressed (part of) the CRMs value and several initiatives have contributed to gather (part of) the related community into clusters and associations. This led to the production of important knowledge, unfortunately disseminated. Numerous databases have also been developed, sometimes as duplicates. For the first time in the history, SCRREEN aims at gathering European initiatives, associations, clusters, and projects working on CRMs into along lasting Expert Network on Critical Raw Materials, including the stakeholders, public authorities and civil society representatives. SCRREEN will contribute to improve the CRM strategy in Europe by (i) mapping primary and secondary resources as well as substitutes of CRMs, (ii) estimating the expected demand of various CRMs in the future and identifying major trends, (iii) providing policy and technology recommendations for actions improving the production and the potential substitution of CRM, (iv) addressing specifically WEEE and other EOL products issues related to their mapping and treatment standardization and (vi) identifying the knowledge gained over the last years and easing the access to these data beyond the project. The project consortium also acknowledges the challenges posed by the disruptions required to devlop new CRM strategies, which is why stakeholder dialogue is at the core of SCRREEN: policy, society, R&D and industrial decision-makers are involved to facilitate strategic knowledge-based decisions making to be carried out by these groups. A specific attention will also be brought on informing the general public on our strong dependence on imported raw materials, on the need to replace rare materials with substitutes and on the need to set up innovative and clean actions for exploration, extraction, processing and recycling.
Agency: Cordis | Branch: H2020 | Program: RIA | Phase: EeB-02-2014 | Award Amount: 3.40M | Year: 2015
EVENT will develop, demonstrate and validate a cost effective, high energy efficient, low CO2 emissions, replicable, low intrusive, systemic approach for retrofitting of residential and commercial buildings, able to achieve NZEB retrofit standard levels, through the integration of an innovative adaptive ventilated faade system, including: Embedded, breakthrough smart modular heat recovery units, which allow thermal storage mode High efficient photovoltaic generation capability units Cost-effective, easy to install, high performance adapted products for external thermal insulation Energy efficient HVAC systems The developed technologies will be integrated in the ventilated faade, and a real time intelligent faade management system will control operation of the system based on meteorological prediction methods for forecasting in advance the decentralised electricity production and the energy (electrical and thermal) demand of the building enabling maximum RE usage. It will inter-operate with existing or latest state-of-the-art Building Energy Management System, to achieve optimum energy efficiency by reducing primary energy needs, CO2 emissions and peak loads, assuring at least the same comfort levels required by Member States Building Codes, at an affordable price. Foreseen impact will be: Energy savings of more than 40%, by the holistic use of the ventilated faade, the heat recovery of ventilation air At least a reduction of 40% of CO2 emissions, as a consequence of the achieved primary energy savings Reduced thermal and electrical peak loads Typical performance target of less than 25 kWh/m 2 year (excluding appliances) Use of heat recovery units, number of photovoltaic cells, natural lighting strategies, and insulation thickness; are variable depending on the characteristics of the building to be retrofitted. Therefore EVENT retrofitting system can be adaptable to different types of buildings and climates, which makes the system versatile.
Agency: Cordis | Branch: H2020 | Program: IA | Phase: NMBP-17-2016 | Award Amount: 6.31M | Year: 2017
NEXTOWER shall introduce a set of innovative materials to boost the performance of atmospheric air-based concentrated solar power (CSP) systems to make them commercially viable. In particular, tower systems are appealing for the great environmental compatibility and offer tremendous potential for efficient (electrical and thermal) power generation. Yet, their industrial exploitation has been so far hindered by limitations in the materials used both for the central receiver - the core component - and for thermal storage. Such limitations dictate maximum working temperature and in-service overall durability (mainly driven by failure from thermal cycling and thermal shocks). Improving the efficiency of a tower system entails necessarily improving the central receiver upstream and possibly re-engineering the whole systems downstream to work longer and at much higher temperature, especially in the thermal storage compartment. NEXTOWER will address this need by taking a comprehensive conceptual and manufacturing approach that will optimize bulk and joining materials for durability at the component level to achieve 25 years of maintenance-free continued service of the receiver and maximum thermodynamic efficiency at the system level. This is made possible through a unique combination of excellence in materials design and manufacturing, CSP full-scale testing facilities brought together in the Consortium, supporting the making of a new full scale demo SOLEAD (in Turkey) within the project. The successful achievement of a new generation of materials allowing for virtually maintenance free operations and increased working temperature shall result in the next-generation of air-coolant CSP highly competitive over other CSP alternatives and sustainable power supply options.
Agency: Cordis | Branch: H2020 | Program: CSA | Phase: H2020-TWINN-2015 | Award Amount: 996.00K | Year: 2016
The main objective of the proposal is to create a virtual centre to boost IMNR position in Bucharest-Ilfov region and Romania by increasing the knowledge and technology degree of innovation potential for sustainable advanced materials operating under extreme condition. Development and understanding of these materials open new opportunities to enhance the competitiveness of regional and National SMEs in the priority machinery and equipment sector. The concept of the virtual centre SUPERMAT stands on: Significantly improving scientific capacity of IMNR in novel nano/micro structured materials under extreme conditions; Implementing innovation actions and boosting entrepreneurship; Improving the technology transfer and services offered by IMNR at Bucharest-Ilfov region, National and European levels; Extend synergies between IMNR and the 6 Research Centres from France, Spain, Italy, Sweden and Italy and ensure continuation of the virtual centre after project end. The proposed support activities will foster the progress the field by: improving existing modelling and simulation tools for ab-initio design of novel multimaterials for extreme environments, select case studied materials with high application potential in energy equipment and machinery, propose best available technologies for selected materials, propose characterisation methods to be certified for future standardisation, organise specific workshops, seminars and conferences with industry, local and National Governmental Agencies, ONGs, organise summer schools and training for young researchers from IMNR, propose an European curricula for PhD students in the field of materials for extreme conditions, dissemination of the results on large scale. The sustainability and continuity of the virtual centre SUPERMAT will be ensured by proposing joint collaborative research projects for H2020 and National projects calls and involvement in the strategy of EIT Nanofutures and Critical Raw Materials.
Agency: Cordis | Branch: H2020 | Program: RIA | Phase: PHC-14-2015 | Award Amount: 4.59M | Year: 2016
This project will develop an innovative therapeutic approach for the treatment of Cystic Fibrosis (CF). This condition originates from the defective function of the CFTR protein, a chloride and bicarbonate permeable transmembrane channel. This project will evaluate small molecules capable of facilitating the transmembrane transport of anions such as chloride and bicarbonate and will thus enable CF treatment by replacing the missing CFTR anion permeation activity. This represents an unexplored path in the treatment of CF and a paradigm shift with respect to current strategies searching for a cure for CF. Instead of focusing on the development of mutation-specific treatments, we plan to develop a therapy applicable to CF patients, regardless of the type of mutation they harbor. Thus, this therapeutic approach overcomes the limitation of current mutation-specific treatments and is applicable to CF patients in general. To achieve this goal we have set up a comprehensive program to validate a research concept and complete the preclinical development of a new lead compound, making it ready for early clinical development. A rmultidisciplinary team of qualified researchers have been assembled to bring to conclusion a truly translational project from the synthesis of new compounds to validation on animal models. Cystic Fibrosis affects more people than any other rare disease. Therefore, it could be said, at least in quantitative terms, that CF qualifies as the main target of the topic. This project aims to complete the preclinical development of novel, innovative drugs based on a radically new concept in Cystic Fibrosis therapies. This result fully addresses the expected impact set out in the work programme of advancing the development of new therapeutic options for patients living with rare diseases as well as contributing to reach the IRDiRC objective to deliver 200 new therapies for rare diseases by 2020.
Agency: Cordis | Branch: H2020 | Program: MSCA-ITN-ETN | Phase: MSCA-ITN-2016 | Award Amount: 3.51M | Year: 2017
SOLUTION will provide research and training program for 14 early stage researchers (ESR) pursuing their PhD in various disciplines covering the broadly defined area of solid lubricant coatings. The project combines theoretical approaches represented by advanced nanoscale simulations, laboratory design and fabrication of novel solid lubricants supported by simulations, and the up-scaling of promising solutions and their application in selected emerging engineering applications. SOLUTION will link industries from various areas dealing with similar issues through intensive training and knowledge sharing. Three topics driven by industrial partners have been selected to demonstrate the added value of simultaneous development and training. The use of modern solid lubricants underlines the transformation of industry towards smart design, which is based on predictive models and cross-communication throughout the entire production chain. Fellows supported by the project will have a unique opportunity to gain competence ranging from simulation, characterization and processing, to industrial processes and entrepreneurship. Highly individualized multidisciplinary training reflecting actual market needs, together with scientific excellence, will generate an open-mind generation able to harvest multidisciplinary knowledge and to successfully face challenges represented by the design of competitive solid lubricants.
Agency: Cordis | Branch: H2020 | Program: MSCA-RISE | Phase: MSCA-RISE-2016 | Award Amount: 841.50K | Year: 2017
The number of biobanks for diagnostic/clinical/biodiversity preservation purposes is increasing exponentially, representing an economic burden for the EU. Cryopreservation (Liquid Nitrogen LN) is the only cells/gametes long-term repository method. LN storage is expensive though, requires dedicated facilities, is hazardous, carries pathogens and has high carbon footprint. DRYNET objective is to set an inter-sectorial/multidisciplinary/international network between EU academic (5), SME (3), the EU pan-Biobank, and international partners (Japan/Thailand), with the aim of sharing knowhow & expertise to lay down the theoretical and early empirical basis for the dry storage of cells/germplasm. DRYNET merges the partners expertise, theoretical/ biophysical/ mathematical modelling, cellular/ molecular/ insect biology, embryology, mechanical engineering into a coherent approach towards dry storage of cells/germplasm. International/inter-sectorial secondments, with meeting/workshop/summer school will be primary tools to implement our strategy for biobanking. Outreaching activities will guarantee public awareness of the project. DRYNETs relies on water subtraction to induce a reversible block of metabolism, a survival strategy available in nature (anhydrobiosis). The work plan foresees the exploitation of natural xero-protectants (Late Embryogenesis Abundant proteins), loaded/expressed in gametes/cells, before drying. The best drying approaches, supported by theoretical/biophysical/math modelling, will be implemented by SMEs/academy partners. DRYNET will bring a simplification of currents practices, with cost and carbon footprint reduction, for the maintenance/shipping of biobanks. DRYNET will generate young scientists with transferable skills, ensuring career prospect in academia/industry. DRYNET strengthens the international/sectorial network between different disciplines, ensures long-term sustainability of the project, and boosts European competitiveness in biobanking.