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Rummens F.,University of Bordeaux 5218 F 33400 Talence France | Ygorra S.,University of Bordeaux 5218 F 33400 Talence France | Mayiss Boussamba H.C.,University of Bordeaux 5218 F 33400 Talence France | Renaud S.,University of Bordeaux 5218 F 33400 Talence France | Lewis N.,University of Bordeaux 5218 F 33400 Talence France
International Journal of Circuit Theory and Applications

This paper presents a theoretical study and the resulting architecture of an analogue-based standard deviation (SD) estimator, typically used in biomedical spike detectors to assess the noise level of bioelectrical recordings online. This well-known circuit generated a significant inaccuracy, so the aim was to increase the efficiency of spike detection through proper calculation of the noise SD, by developing a rigorous, original theoretical study. The approach consisted of establishing behavioural models for the SD estimation circuit to obtain a transfer function and compare different controllers. This modelling approach also highlighted the parameters available and the impact of their relationships on design optimisation. The behavioural models, inherently based on approximations, were then initially validated by comparing them with actual circuit behaviour, obtained using discrete components. These comparisons revealed that the models matched the actual circuit measurements. Finally, taking into account the conclusions of our theoretical study, an integrated version of this adaptive threshold spike detector was designed using 0.35-μm complementary metal-oxide-semiconductor technology. Simulations of this circuit revealed that the proposed controller eliminated the static error and ensured efficient spike detection. © 2016 John Wiley & Sons, Ltd. Source

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