Fayetteville, AR, United States
Fayetteville, AR, United States

The University of Arkansas is a public, co-educational, land-grant, space-grant, research university located in Fayetteville, in the U.S. state of Arkansas. It is the flagship campus of the University of Arkansas System which comprises six main campuses within the state – the University of Arkansas at Little Rock, the University of Arkansas at Monticello, the University of Arkansas at Pine Bluff, the University of Arkansas at Fort Smith, and the University of Arkansas for Medical science. Over 25,000 students are enrolled in over 188 undergraduate, graduate, and professional programs. It is classified by the Carnegie Foundation as a research university with very high research activity. Founded as Arkansas Industrial University in 1871, its present name was adopted in 1899 and classes were first held on January 22, 1872. It is noted for its strong architecture, agriculture , business, communication disorders, creative writing, history, law, and Middle Eastern studies programs.The University of Arkansas completed its "Campaign for the 21st Century" in 2005, in which the university raised more than $1 billion for the school, used in part to create a new Honors College and significantly increase the university's endowment. Among these gifts were the largest donation given to a business school at the time , and the largest gift given to a public university in America , both given by the Walton Family Charitable Support Foundation.Total enrollment for the fall semester of 2013 was 25,365. The university campus comprises exactly 360 buildings on 512 acres , including Old Main, the first permanent academic building erected, and The Inn at Carnall Hall, which serves as an on-campus hotel and restaurant facility. Academic programs are in excess of 200. The ratio of students to faculty is 19:1. Wikipedia.


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Patent
Ochsner Clinic Foundation, Kagawa University and University of Arkansas | Date: 2016-12-22

Fusion proteins containing active agonist or antagonist fragments of parathyroid hormone (PTH) and parathyroid hormone related peptide (PTHrP) coupled to a collagen-binding domain are presented. The fusion proteins can be used to promote bone growth, to promote hair growth, to prevent cancer metastasis to bone, to promote immune reconstitution with a bone marrow stem cell transplant, to promote mobilization of bone marrow stem cells for collection for autologous stem cell transplant, and to treat renal osteodystrophy. Pharmaceutical agents comprising a collagen-binding polypeptide segment linked to a non-peptidyl PTH/PTHrP receptor agonist or antagonist are also presented.


Patent
University of Arkansas, The Kitasato Institute and Montefiore Medical Center | Date: 2016-12-21

Methods of delivering therapeutic agents by administering compositions including a bacterial collagen-binding polypeptide segment linked to the therapeutic agent to subjects in need of treatment with the therapeutic agent are provided. Methods of treating hyperparathyroidism, and hair loss using compositions comprising a collagen binding polypeptide and a PTH/PTHrP receptor agonist are provided. In addition, methods of reducing hair regrowth by administering a composition including a collagen binding polypeptide and a PTH/PTHrP receptor antagonist are provided.


The present disclosure provides compositions and methods for selectively killing senescent cells, wherein the selective killing of senescent cells delays aging and treats age-related disorders.


Patent
University of Arkansas | Date: 2017-02-08

The present disclosure describes disubstituted triazoles, their synthesis, and their use as anti-cancer compounds. In particular, compounds of Formula (I) are provided, examples include 4,5-diaryl-1,2,3-triazoles, 4-aryl-5-heteroaryl-1,2,3-triazoles. These compounds are synthesized by treating diaryl or aryl-heteroaryl substituted olefins with azides in the presence of a proton donor or acceptor. The inhibition of tubulin polymerization using these 1,2,3-triazoles is also described.


A device for measuring strain and volume of a soil sample including an enclosure adapted to receive a soil sample within another enclosure. A base adapted to hold the sample enclosure. The device also has a plurality of moveable arms located between the enclosures which may be a spaced distance apart and adapted to move around the sample. Cameras as included on the arms.


Patent
University of Arkansas | Date: 2016-11-29

Adjuvants comprising chitosan cross-linked with an aldehyde or mannosylated chitosan are provided herein. Methods of making the adjuvants and methods of combining or linking the adjuvants with antigens are also provided. The adjuvant-antigen combinations can be used in vaccine formulations and the vaccine formulations can be used in methods to vaccinate animals against the source of the antigen or to enhance the immune response in a subject.


An autonomous guided vehicle system that provides decentralized coordination and real-time environmental changes in a workspace to a vehicle. The system includes distributed cameras positioned in predetermined locations. The cameras are adapted to communicate with other cameras to coordinate the movement of the vehicles from a source to a destination.


Patent
University of Arkansas and Texas A&M University | Date: 2017-04-12

Adjuvant compositions, vaccines, constructs for preparing the adjuvant compositions and vaccines and methods of using the adjuvant compositions and vaccines to enhance immune responses in subjects are provided herein. In particular, a rapid antibody response to the vaccine including both IgG (in the circulation) and slgA (mucosal secretory IgA) is elicited. The adjuvants and vaccines may be used for sub-cutaneous or mucosal administration enabling low cost, effective vaccination of subjects. A method of epitope mapping to rapidly identify antigenic epitopes is also provided.


Patent
University of Arkansas | Date: 2017-04-26

The present disclosure provides genetically modified animals and cells comprising a polynucleotide encoding human profilin1. Also provided are methods of assessing the effects of agents in genetically modified animals and cells comprising a polynucleotide encoding human profilin1.


Patent
University of Arkansas | Date: 2017-05-17

Compositions including chitosan covalently linked to a cytokine or growth factor are provided herein. The compositions can be used to produce pharmaceutical compositions and can be used in methods of treating a variety of diseases or disorders. The compositions are especially suitable for localized delivery and may allow for intratumoral delivery and treatment of cancers or stimulation of an immune response to a co-administered antigen.

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