Al-Adilee K.J.,University of Al Qadisiya |
Eassa S.M.,University of Al Qadisiya |
Dakhil H.K.,University of Al Qadisiya
Oriental Journal of Chemistry | Year: 2016
The azo reagent 2-((E)-(1H-benzo[d]imidazol2-yl)diazenyl)-5-((E)-benzyl ideneimino) phenol (BIADPI) was prepared and examined by using element analysis (C.H.N.), UV-Vis., Mass spectrum, 1H-NMR spectrum and infrared spectra. A sensitive and selective spectrophotometric method is proposed for the rapid determination of iron (III) and chromium(III) using (BIADPI), as spectrophotometer reagent. The reaction between this reagent with chromium (III) and iron (III) is instantaneous at (586,536) nm (λmax) and pH=(7.5,4) to form perpul complexes having a mole ratio 1 : 2 (metal : ligand) for Cr(III) and Fe(III) the absorbance remains stable for over 24 hours. Beer's law is obeyed in the rang of (1-14) μg.ml-1 and (1-21) μg.ml-1 with molar absorptivity (Є) = (7.768×105, 9.3575×105) L.mol-1.cm-1 and a detection limit of (0.275-0.14) μg.ml-1 obtained respectively. The precision and accuracy were obtained to be R.S.D%=(0.9-0.467)%,Re%=(99.1-98.2-)% and Erel%= (-1.8 - 0.9)%.The method is successfully employed for the determination of iron(III) in Pharmaceutical preparations (Anemia drugs). The most important interferences were due to Ni(II), Zn(II), Co(II), Cd(II), Cu(II) and Hg(II) and suitable masking agents were used. © 2016, Oriental Scientific Publishing Company. All rights reserved.
Abdul-Rida N.A.,University of Al Qadisiya |
Mohammed T.I.,University of Al Qadisiya |
Al-Masoudi N.A.,University of Basrah |
Frotscher M.,Saarland University
Medicinal Chemistry Research | Year: 2017
A new series of 2-amino-4-alkylamino-6-methylamino-5-nitrosopyrimidine derivatives 10–14 have been synthesized from 5-nitrosopyrimidine analog 9 by nucleophilic aromatic substitution reaction with various amines using dimethylformamide as a solvent at 70–90 °C. Similarly, various 4-alkylamino-5-nitrosopyrimidine analogs 16–24 were obtained from 9 and primary and secondary amines using dichloromethane at room temperature. Analogously, treatment of 9 with 2-thioglycolic acid afforded 4-thioalkyl derivative 15. Treatment of 9 with chloroacetyl chloride (26) gave the corresponding chloroacetamido analog 27, which afforded the desired 2-(benzothiazol-2-ylthio)-N-(4-isopropoxy-6-(methylamino)-5-nitrosopyrimidine-2-yl)acetamide (29) on treatment with 2-mercaptobenzothiazole (28) in the presence of triethylamine and dichloromethane. Condensation of 9 with butyraldehyde in acidic ethanol gave the corresponding 2-butylideneamino analog 30. Selected examples of the synthesized compounds were evaluated for their 17β-hydroxysteroid dehydrogenase type 1 and 2 (17β-HSD1 and 2) inhibitory activity. Futhermore, same compounds were evaluated for their antiproliferative activity against two solid tumour-derived cell lines consisting Hep-G2 (human hepatocarcinoma) and MCF-7 (breast cancer). © 2017 Springer Science+Business Media New York
Al-Sibahy A.,University of Manchester |
Al-Sibahy A.,University of Al Qadisiya |
Edwards R.,University of Manchester
Construction and Building Materials | Year: 2014
This paper presents an experimental investigation and analytical simulation which aim to assess the behaviour of a new type of masonry wallette under conditions of an axial compression load at ambient temperature. Two different masonry wallettes were produced using two types of lightweight concrete blocks, the first incorporating expanded clay and the second using by-product materials which consisted of recycled waste glass and metakaolin. Both vertical and lateral deformations were measured at different positions on the wallette specimens. The load-bearing capacity was also determined. The measured results obtained were compared with analytically simulated results produced by the Abaqus/Standard finite element package. The experimental results showed that the maximum axial loads at failure were 474 kN and 558 kN for the reference and modified wallettes respectively implying corresponding bearing capacities of 7.1 MPa and 8.3 MPa. The critical path of the failure mode was similar for all of the wallettes tested and normally began underneath the load point, then passed through the concrete blocks and head joint to reach the wallette toe. The most influential factors on the analytical model are the value of penalty stiffness and imperfect wallette construction. A close agreement between the measured and simulated results has been observed, suggesting that finite element analysis provides a reliable alternative to further laboratory measurements. © 2014 Elsevier Ltd. All rights reserved.
PubMed | University of Al Qadisiya, Center for Translational Studies, University of South Carolina and Nahrain University
Type: | Journal: BioMed research international | Year: 2015
Human Cytomegalovirus (HCMV) is an endemic herpes virus that reemerges in cancer patients enhancing oncogenic potential. HCMV infection is associated with certain types of cancer morbidity such as glioblastomas. HCMV, like all other herpes viruses, has the ability to remain latent within the body of the host and can contribute in chronic inflammation. To determine the role of HCMV in glioma pathogenesis, paraffin-embedded blocks from glioma patients (n = 50) and from benign meningioma patients (n = 30) were obtained and evaluated by immunohistochemistry and polymerase chain reaction for the evidence of HCMV antigen expression and the presence of viral DNA. We detected HCMV antigen and DNA for IEI-72, pp65, and late antigen in 33/36, 28/36, and 26/36 in glioblastoma multiforme patients whereas 12/14, 10/14, and 9/14 in anaplastic astrocytoma patients, respectively. Furthermore, 84% of glioma patients were positive for immunoglobulin G (IgG) compared to 72.5% among control samples (P = 0.04). These data indicate the presence of the HCMV virus in a high percentage of glioma samples demonstrating distinct histopathological grades and support previous reports showing the presence of HCMV infection in glioma tissue. These studies demonstrate that detection of low-levels of latent viral infections may play an active role in glioma development and pathogenesis.
Abdulbaqi H.S.,Universiti Sains Malaysia |
Abdulbaqi H.S.,University of Al Qadisiya |
Jafri M.Z.M.,Universiti Sains Malaysia |
Omar A.F.,Universiti Sains Malaysia |
And 2 more authors.
AIP Conference Proceedings | Year: 2014
Brain tumors, are an abnormal growth of tissues in the brain. They may arise in people of any age. They must be detected early, diagnosed accurately, monitored carefully, and treated effectively in order to optimize patient outcomes regarding both survival and quality of life. Manual segmentation of brain tumors from CT scan images is a challenging and time consuming task. Size and location accurate detection of brain tumor plays a vital role in the successful diagnosis and treatment of tumors. Brain tumor detection is considered a challenging mission in medical image processing. The aim of this paper is to introduce a scheme for tumor detection in CT scan images using two different techniques Hidden Markov Random Fields (HMRF) and Fuzzy C-means (FCM). The proposed method has been developed in this research in order to construct hybrid method between (HMRF) and threshold. These methods have been applied on 4 different patient data sets. The result of comparison among these methods shows that the proposed method gives good results for brain tissue detection, and is more robust and effective compared with (FCM) techniques. © 2015 AIP Publishing LLC.
Mutar M.A.,University of Al Qadisiya
Asian Journal of Chemistry | Year: 2014
Six new aromatic Co-polyamides CoP1-CoP6 were prepared by direct Yamazaki's polycondensation reaction of various aliphatic and aromatic dicarboxylic acid (adipic acid, phthalic acid, terephthalic acid and 4-phenylenediacrylic acid) with new various types of aromatic diamine monomers: monomers containing flexible linkages (methylene group), Schiff-base diamine monomer and diamine monomer containing pyridine heterocyclic group and bearing bulky aromatic pendant groups in the 4-position of the pyridine ring, in the presence of LiCl in pyridine and triphenyl phosphite as condensing agents in N-methyl-2-pyrrolidinone as solvent. 4-Phenylenediacrylic acid (PPDAA) was prepared by the condensation reaction of terephthalaldehyde with malonic acid in the presence of pyridine. The monomers were characterized by FTIR and 1H NMR. The resulting polyamides were characterized by FTIR and 1H NMR and their physical properties including solubility, thermal stability and thermal behaviour were studied as well. All of these new polymers show good solubility in polar aprotic solvents and very good thermal stability. © 2014, Chemical Publishing Co. All rights reserved.
Al-Taweel S.S.,University of Al Qadisiya
Asian Journal of Chemistry | Year: 2014
In the present study, locally base of palm leaf was used as a natural adsorbent for removing of textile dye (azure B) from aqueous solution. The effect of initial dye concentration, contact time, weight of adsorbent and temperature (25,35 and 50°C) were investigated. The per cent of dye removal increased with increasing base of palm leaf mass and the adsorption process was reached equilibrium after 60 min. The adsorption isotherms are of H-type according to Gile's classification. The calculated data were analyzed using Langmiur, Freundlich and Dubinin-R isotherms, the results show that the adsorption process was better described by Langmiur isotherm than the other isotherms. Langmiur constants were also calculated. The basic thermodynamic functions were evaluated (ΔH, ΔG, ΔS) and it was found that interaction of dye with the surface was exothermic and spontaneous. The adsorption mechanism and the nature of interaction between surface and azure B dye was studied by using FTIR spectroscopy. Pseudo-first order and pseudo-second order models were applied to experimental data at all temperatures (25, 35 and 50°C), the adsorption followed pseudo-second order rate expression and the intraparticle diffusion may plays a role in the adsorption process. The activation energy of process was determined as 46.36 kJ/mol at 298 K. The adsorption of dye on base of palm leaf surface may be chemisorption in nature as indicated from desorption experiment. © 2014, Chemical Publishing Co. All rights reserved.
Mutar M.A.,University of Al Qadisiya |
Mutashar M.O.,University of Al Qadisiya
Asian Journal of Chemistry | Year: 2014
Several systematically varied aromatic polyimides were prepared by solution polycondensation reaction of different dianhydrides (pyromellitic dianhydride), 3,3′4,4′-benzophenone tetra-carboxylic dianhydride and 4,4′-hexafluoroisopropylidenebis(phthalic anhydride), with various structurally different diamines containing halogens and phosphorus components using a standard two-stage process with thermal imidization of poly(amic acid). Chemical structures, of these materials were characterized with FT-IR, NMR, elemental analysis. Thermal analysis of thermal gravimetricanalysis (TGA) reveals that these resulted aromatic polyimides (P1-P4) possess thermal stability. Furthermore, high char yields in TGA analysis values indicate that these halogens and phosphorus containing aromatic polyimidespossess excellent flame retardant properties. © 2014, Chemical Publishing Co. All rights reserved.
Esmail E.L.,University of Al Qadisiya
Journal of Mechanical Design, Transactions of the ASME | Year: 2012
This paper presents proposed designs of parallel hybrid transmissions with only one electric motor/generator (MG) and without any rotating clutches. The proposed motor/generator integrated hybrid transmission serves to regulate the engine's effective gear ratio (engine rotational velocity versus vehicle velocity) by mixing the engine and electric motor powers through a power controlling device. The proposed design provides some of the benefits and flexibility of a power-split design but using conventional available components in a simpler mechanical layout that makes the design compact, mechanically simple, and operationally flexible. Three commonly used transmission gear sets are used for this purpose; Simpson, Ravigneaux, and Type-6206 gear sets. With an electronic control unit, eight major modes of operation including a regenerative braking capability are shown to be feasible in the proposed hybrid transmission; one electric motor mode, two engine modes, two engine/charge modes, and two power modes. Continuously variable transmission (CVT) capability is provided with the second engine/charge mode and with the second power mode. The second power mode can be further subdivided into three hybrid submodes that correspond to the direct drive, underdrive, and overdrive of a conventional automatic transmission. The feasibility of the proposed hybrid transmission is demonstrated with a numerical example employing conventional Ravigneaux gear train. The kinematics, static torque, and power flow relations for all operation modes are analyzed in detail. © 2012 American Society of Mechanical Engineers.
Al-Adely K.J.,University of Al Qadisiya
Asian Journal of Chemistry | Year: 2012
This paper reports the preparation and identification of Ni(II), Pd(II), Pt(IV), Cu(II), Ag(I) and Au(III) metal complexes with new aryl thiazolyl azo 2-[2-(6-methoxy benzothiazolyl)azo]-4-nitro phenol (6-MBTANP = HL). The structure of the isolated chelat complexes characterized by elemental analysis, IR, electronic spectral, magnetic moment and molar conductivity. The obtained results indicated that the ligand (6-MBTANP) behaves as a tridentate chelating agent with 1:1 and 1:2 (metal:ligand) complexes. Investigation of the stereochemistry of these chelat complexes showed that, Ni(II), Cu(II) and Pt(IV) complexes are octahedral while Pd(II) and Au(III) complexes are square planer and Ag(I) complex is tetrahedral geometry. Conductance measurements suggest the 1:2 electrolytic nature of the Pt(IV) and (1:1) electrolytic nature of the Au(III) complexes but non-electrolytic nature of remaining complexes. The analytical data show the existence of coordination water in Ni(II), Pt(IV), Cu(II), Ag(I) and Au(III) complexes. Stability constants of complexes were calculated by spectrophotometrically.