Aberdeen, United Kingdom

University of Aberdeen

www.abdn.ac.uk
Aberdeen, United Kingdom

The University of Aberdeen is a public research university in the city of Aberdeen, Scotland. It is an ancient university founded in 1495 when William Elphinstone, Bishop of Aberdeen, petitioned Pope Alexander VI on behalf of James IV, King of Scots to create King's College. This makes it Scotland's third-oldest university and fifth-oldest in the English-speaking world. The university as it is today was formed in 1860 by a merger between King's College and Marischal College, a second university founded in 1593 in Aberdeen city centre as a Protestant alternative to King's College. Today, the University of Aberdeen is consistently ranked among the top 150 universities in the world and is one of two universities in Aberdeen, the other being The Robert Gordon University.The university's iconic buildings act as symbols of the City of Aberdeen, particularly Marischal College in the city centre and the spire of King's College in Old Aberdeen. There are two campuses; the main King's College campus is at Old Aberdeen approximately two miles north of the city centre, around the original site of King's College, although most campus buildings were constructed in the 20th century during a period of expansion. The university's Foresterhill campus is located next to Aberdeen Royal Infirmary and houses the School of Medicine and Dentistry and School of Medical science.The University has approximately 13,500 students from undergraduate to doctoral level, including many international students. In addition, the university's Centre for Lifelong Learning acts as an extension college, offering higher education courses to the local community even for those without the usual qualifications for admission to degree-level study. A full range of disciplines are offered and in 2012 the university offered over 650 undergraduate degree programmes.Five Nobel Prize winners are associated with the University. Other academics and graduates of the University include many distinguished figures, including: physicist James Clerk Maxwell; Thomas Reid, the founder of the Scottish School of Common Sense and an important figure in the Scottish Enlightenment; philosopher Robert Adamson; educationalist and philosopher Alexander Bain; and theologian William Robinson Clark. Wikipedia.

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Patent
ApaTech Ltd and University of Aberdeen | Date: 2017-01-27

A synthetic calcium phosphate-based biomedical material comprising gadolinium. The material may comprises a compound having the general chemical formula: Ca_(10y)Gd_(y)(PO_(4))_(6x)(SiO_(4))x(OH)_(2c+y )where 0


Patent
University of Aberdeen | Date: 2017-03-22

The present invention relates to methods of producing pancreatic endocrine cells and uses of the cells obtained using the methods. The method utilises inhibitors or combinations of factors to provide increased quantities of endocrine material, for example for transplantation purposes.


Patent
University of Toronto and University of Aberdeen | Date: 2017-07-05

The present disclosure relates to indole derivatives of the formula (I) which are cannabinoid type 1 receptor modulators and which are useful in the treatment of diseases in which modulation of the receptor is beneficial; to processes for their preparation; to pharmaceutical compositions comprising them; and to methods of using them.


Patent
University of Aberdeen and Lothian Health Board | Date: 2015-05-14

The present invention relates to methods of producing pancreatic endocrine cells and uses of the cells obtained using the methods. The method utilises inhibitors or combinations of factors to provide increased quantities of endocrine material, for example for transplantation purposes.


Patent
University of Aberdeen | Date: 2017-03-22

The present invention provides methods and materials relating to obtaining or expanding populations of islet cells, and uses of the islet cells obtained by these methods, for example in the treatment of diabetes. The invention uses transcription factors in a process of expansion and de-differention, followed by redifferentiation.


Patent
University of Aberdeen and Lothian Health Board | Date: 2015-05-14

The present invention provides methods and materials relating to obtaining or expanding populations of islet cells, and uses of the islet cells obtained by these methods, for example in the treatment of diabetes. The invention uses transcription factors in a process of expansion and de-differention, followed by redifferentiation.


Patent
University of Aberdeen | Date: 2016-09-22

The present invention provides a single domain specific binding molecule having the structure FW1-CDR1-FW2-HV2-FW3a-HV4-FW3b-CDR3-FW4 in which the Framework Regions FW1, FW2, FW3a, FW3b, and FW4, the Complementarity Determining Regions CDR1 and CDR3, and the Hypervariable Regions HV2, and HV4 have amino acid sequences as defined which provide a high affinity anti-human serum albumin (HSA) binding domain.


Patent
University of Aberdeen and University of St. Andrews | Date: 2017-09-13

This invention relates to an engineered leader-independent heterocyclase (also known as a cyclodehydratase) comprising a defined cyanobactin leader sequence which drives the efficient conversion of heterocyclisable amino acids, such as Ser, Thr and Cys, within a peptide substrate lacking a leader sequence into heterocycles produce a homogenous heterocycle-containing product. This may be useful in biotechnology and chemical synthesis.


Brown G.D.,University of Aberdeen
Annual Review of Immunology | Year: 2011

Fungal diseases have emerged as significant causes of morbidity and mortality, particularly in immune-compromised individuals, prompting greater interest in understanding the mechanisms of host resistance to these pathogens. Consequently, the past few decades have seen a tremendous increase in our knowledge of the innate and adaptive components underlying the protective (and nonprotective) mechanisms of antifungal immunity. What has emerged from these studies is that phagocytic cells are essential for protection and that defects in these cells compromise the host's ability to resist fungal infection. This review covers the functions of phagocytes in innate antifungal immunity, along with selected examples of the strategies that are used by fungal pathogens to subvert these defenses. © 2011 by Annual Reviews. All rights reserved.


Prosser J.I.,University of Aberdeen
Nature Reviews Microbiology | Year: 2015

Technological advances are enabling the sequencing of environmental DNA and RNA at increasing depth and with decreasing costs. Metagenomic and transcriptomic analysis of soil microbial communities and the assembly of 'population genomes' from soil DNA are therefore now feasible. Although the value of such 'omic' approaches is limited by the associated technical and bioinformatic difficulties, even if these obstacles were eliminated and 'perfect' metagenomes and metatranscriptomes were available, important conceptual challenges remain. This Opinion article considers these conceptual challenges in the context of the current use of omics in soil microbiology, but the main arguments presented are also relevant to the application of omics to marine, freshwater, gut or other environments. © 2015 Macmillan Publishers Limited. All rights reserved.

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