University Mohammed Premier
Oujda, Morocco
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Agency: European Commission | Branch: FP7 | Program: CP | Phase: ENERGY.2009.5.2.2 | Award Amount: 3.13M | Year: 2010

COMET aims at identifying and assessing the most cost effective CO2 transport and storage infrastructure able to serve the West Mediterranean area, namely Portugal, Spain and Morocco. This is achieved considering the time and spatial aspects of the development of the energy sector and other industrial activities in those countries as well as the location, capacity and availability of potential CO2 storage geological formations. Special attention is given to a balanced decision on transport modes, matching the sources and sinks, addressing safety and lifetime objectives, meeting optimal cost - benefit trade-off, for a CCS network infrastructure as part of an international cooperation policy. The need for a joint CCS infrastructure in the West Mediterranean is related to the geographical proximity, to the increasing connections between the energy and industrial sectors in the area, to the continuity of sedimentary basins that can act as possible storage reservoirs and to the existing experience in managing a large gas transport infrastructure, such as the natural gas pipeline coming through Morocco, to Spain and Portugal. The consortium is coordinated by INETI (Portugal), and comprises 7 research institutions, 4 Universities, 1 SME and 5 energy companies from 6 European countries and Morocco. COMET aims to optimise the connection between sources and sinks by comparing the several possible transport modes (pipelines, trains, ships and trucks) and existing and to be realized infrastructures and expects to find the least-cost transport mode and routes from clusters to sinks. It is expected that each source cluster will be rigorously matched to the most suitable sink, while minimising the required investment in infrastructures and taking advantage of the effect of scale associated to an integrated infrastructure. COMET will be an important step towards the safe and commercial deployment of large scale near zero emission power plants in SW Europe and North Africa.

Abdesslam B.,University Mohammed Premier
African journal of reproductive health | Year: 2011

Moroccan population has known a growing demographic trend. However, beyond the global tendency, reproductive health remains characterised by inequalities and disparities between urban and rural, rich and poor, developed and deprived regions. In this study, we relied mainly on data and statistics provided by the last five censuses, the four Demographic Health Surveys, Multiple Indicator Cluster Surveys, reports of international bodies and publications dealing mainly with health and development in the Arab World. During the last decades, fertility declined due to different parameters. Infant mortality decreased and should reach the corresponding Millennium Development Goal whereas maternal mortality has stayed nearly constant. The achievements accomplished in reproductive health remain insufficient. Family planning and contraception policies need to reach more women; and antenatal and postnatal care should be enhanced especially towards poor women living in rural areas and deprived regions.

Isaad J.,University of Lille Nord de France | El Achari A.,University of Lille Nord de France | Malek F.,University Mohammed Premier
Dyes and Pigments | Year: 2013

Starch films containing a chemodosimeter probe based on a quinolinium merocyanine dye were successfully prepared and studied. Through the selective nucleophilic addition reaction between cyanide anions and the dye chromophore the film can selectively detect sub-micromolar quantities of cyanide ion by a distinct color change. © 2012 Elsevier Ltd. All rights reserved.

Bentata Y.,University Mohammed Premier
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia | Year: 2013

Numerous studies have shown that diabetic nephropathy (DNP) is associated with an elevated risk of progression toward end-stage renal disease (ESRD) as well as increased cardiovascular mortality. The majority of these studies are from the developed countries. The factors leading to the progression of DNP may not be quite the same in the developing countries. The aim of this study was to evaluate the risk factors of progression toward ESRD and mortality among type-1 diabetes (T1D) patients with DNP in a developing country. This prospective study was conducted enrolling 72 patients with T1D in September 2006, including T1D patients with DNP defined as microalbuminuria, proteinuria, and/or renal failure, and following them up for five years. The mean age was 29.5±7.5 years with a mean duration of diabetes of 17 (11-20) years. At the time of enrollment, 43.1% had arterial hypertension, 69.4% had proliferative retinopathy, 44.4 had clinical neuropathy, 25% lived in rural areas, and 51.4% had macroalbuminuria. Progression toward ESRD was observed in 34.7% of cases. In multivariate analysis, diastolic blood pressure (P = 0.006) and blood hemoglobin (P = 0.003) were identified as the risk factors associated with ESRD. Death occurred in 18.3% of cases, including 92.3% on hemodialysis with a median hemodialysis duration of six (1-60) months. In multivariate analysis, the ESRD was identified as risk factor for death (P <0.001). DNP due to T1D remains a disease involving a heavy burden of morbi-mortality and is difficult to manage in a developing country because of the low socioeconomic level of patients and the lack of reliable epidemiological data.

Gadi D.,University Mohammed Premier
Journal of complementary & integrative medicine | Year: 2012

Blood platelets are directly involved in both haemostatic and pathologic thrombotic processes, through their adhesion, secretion and aggregation. In this study, we investigated the effect of genins (aglycone flavonoids without sugar group) isolated from parsley (Petroselinum crispum) leaves in vitro on human platelet aggregation and adhesion to a collagen-coated surface under physiologic flow conditions. Materials and Methods: The aggregation and adhesion studies were monitored after pre-incubation of platelets with genins. Genins inhibited dose dependently aggregation induced by thrombin, ADP and collagen. The strongest effect was observed in collagen induced aggregation (IC50 = 0.08 ± 0.01 mg/ml). The HPLC identification of genins compounds revealed the presence of keampferol, apigenin and other not identified compounds. The aggregation tests showed that these compounds have anti-aggregating activity. In addition, adhesion of human platelets to collagen was greatly decreased (over 75 %) by genins (0.3 mg/ml). While the mechanism by which genins act is unclear, we suggest that these compounds may interfere with a multiple target step in the haemostasis process. These results show that genins isolated from parsley has a potent antiplatelet activity. It may be an important source of beneficial antiplatelet compounds that decrease thrombosis and cardiovascular diseases.

Boutayeb A.,University Mohammed Premier | Boutayeb S.,National Institute of Oncology | Boutayeb W.,University Mohammed Premier
International Journal for Equity in Health | Year: 2013

Introduction. Non communicable diseases are the biggest cause of death worldwide. Beside mortality, these diseases also cause high rates of morbidity and disability. Their high prevalence is generally associated to multi-morbidity. Because they need costly prolonged treatment and care, non communicable diseases have social and economical consequences that affect individuals, households and the whole society. They raise the equity problem between and within countries. Methods and limitations. This annotated bibliography is a systematic review on multimorbidy of non communicable diseases and health equity in WHO Eastern Mediterranean countries. Medline/PubMed, EMBASE and other sources were used to get peer reviewed papers dealing with the review theme. The words/strings used for search and inclusion criteria were: multimorbidity, comorbidity, equity, non communicable diseases, chronic diseases, WHO Eastern Mediterranean and Arab countries. Bibliography with annotations. According to the inclusion criteria, 26 papers were included in the present review. Generally, lack or paucity of publications was encountered in themes like headache, cancer and respiratory diseases. Of the 26 contributions selected, twelve dealt with comorbidity of depression and mental disorders with other chronic diseases. Another set of 11 publications was devoted to multimorbidity of diabetes, cardiovascular diseases (CVDs), hypertension, metabolic syndrome and obesity. Considering association of multimorbidity and social determinants, this review shows that female gender, low income, low level of education, old age and unemployed/retired are the most exposed to multimorbidity. It should also be stressed that, geographically, no contribution was issued from North African countries.Non communicable diseases are one of the biggest challenges facing health decision makers in WHO Eastern Mediterranean countries where the multidimensional transition is boosting increases in multimorbidity of depression and mental diseases, cardiovascular diseases, diabetes, cancer and respiratory diseases among the whole population but with the highest burden among the least disadvantaged individuals or subpopulations. Health ministries in WHO Eastern Mediterranean countries should pay a particular attention to the association between equity and multimorbidity and opt for cost effective strategies based on early diagnosis and sensitisation for healthy diet, physical activity, no smoking and no alcohol. © 2013 Boutayeb et al.; licensee BioMed Central Ltd.

The goal of this study was to examine the effect of Virgin Argan Oil (VAO) obtained from the fruit of Argania spinosa in a model of type 2 diabetes and hypertensive rats. Neonatal diabetes was induced by a single i.p. injection of streptozotocin (90 mg/kg) 2 days after birth. To induce NO-deficient hypertension, the adult diabetic animals were treated with l-nitroarginine methylester (l-NAME) (30 mg/kg/day) given orally for 21 days. Following treatment with VAO (21 days), the hyperglycemia decreased to 1.3 ± 0.07 g/l compared with 1.92 ± 0.09 g/l (p < 0.01) in the untreated diabetic-hypertensive rats. The simultaneous administration of VAO with l-NAME prevented the increase in blood pressure during the 3 weeks of treatment. Blood pressure remained constant at 131 ± 1 mm Hg after 21 days - vs 157 ± 0.64 mm Hg in untreated animals (p < 0.001). The treatment with VAO to diabetic-hypertensive rats caused a significant increase of hepatic glycogen levels (13.3 ± 1.8 vs 6.34 ± 0.75 mg/g tissue in untreated diabetic-hypertensive control group; p < 0.01). In conclusion, the overall findings indicate that VAO possesses antidiabetic and antihypertensive activity in n-stz/l-NAME rats. This effect may be related to its high content of tocopherols, phenolic compounds, and unsaturated fatty acids.

Abdesslam B.,University Mohammed Premier
BMC Research Notes | Year: 2012

Background: Moroccan authorities carry out regular surveys on population and family health (NSFFP 1980, NSPH 1992, SPFH 2004, NSPFH 2011). These surveys constitute valuable resources for monitoring socio-economic and health indicators. They provide an evidence base for health decision makers to help them to optimize health strategies in order to improve the health conditions of the whole population. They also provide updated measures on geographic disparities, socio-economic inequalities and health inequity. The most recent Moroccan population and family health survey (NSPFH 2011) was carried out between November 2010 and March 2011. The final report and the database are not yet accessible, but a preliminary report was released early March 2012. This report does not allow for a complete evaluation of the present health situation in Morocco. A partial equity analysis can, however, be devoted to the comparison of health indicators especially in terms of rural-urban gaps. Results: The 2011 survey shows that Moroccan population is in the last phase of the demographic transition. The total fertility rate decreased from 5.6 children per woman in 1980 to 2.5 per woman in 2011. The mean age of first marriage increased from 24 years for men and 17.5 years for women in 1960 to 31.5 years and 26.3 years in 2011 for men and women, respectively. The age structure shows a trend of ageing population. A comparison with the 1992 NSPH indicates that adult illiteracy has decreased from 53% in 1992 to 37.6% in 2011. During the same time period, women's access to maternal care and health services improved significantly. For instance, the proportion of deliveries assisted by skilled health personnel increased from 31% in 1992 to 73.6% in 2011. Between 1992 and 2011, neonatal, postnatal, infant and under-five mortality rates were reduced by 44%, 65%, 54% and 64%, respectively. Conclusion: This paper shows that average health indicators improved noticeably during the last two decades but rural-urban disparities are still a challenge for health decision makers. Socio-economic indicators, like illiteracy rate and unemployment, also demonstrate large gender inequalities. This preliminary analysis is designed to assist Moroccan health authorities to evaluate the current health situation in order to adopt cost-effective strategies that improve "health for all" and reduce the gaps between advantaged and disadvantaged populations. © 2012 Boutayeb; licensee BioMed Central Ltd.

University Mohammed Premier | Date: 2013-09-05

A system is provided for the automatic drop-off of at least one object on a conveyor belt for the purpose of the transport of the at least one object. The system includes:

Magrath I.,Uniformed Services University of the Health Sciences | Steliarova-Foucher E.,International Agency for Research on Cancer | Epelman S.,Santa Marcelina Hospital and International Network for Cancer Treatment and Research Brazil | Ribeiro R.C.,St Jude Childrens Research Hospital | And 5 more authors.
The Lancet Oncology | Year: 2013

Patterns of cancer incidence across the world have undergone substantial changes as a result of industrialisation and economic development. However, the economies of most countries remain at an early or intermediate stage of development-these stages are characterised by poverty, too few health-care providers, weak health systems, and poor access to education, modern technology, and health care because of scattered rural populations. Low-income and middle-income countries also have younger populations and therefore a larger proportion of children with cancer than high-income countries. Most of these children die from the disease. Chronic infections, which remain the most common causes of disease-related death in all except high-income countries, can also be major risk factors for childhood cancer in poorer regions. We discuss childhood cancer in relation to global development and propose strategies that could result in improved survival. Education of the public, more and better-trained health professionals, strengthened cancer services, locally relevant research, regional hospital networks, international collaboration, and health insurance are all essential components of an enhanced model of care. © 2013 Elsevier Ltd.

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