Koubachi J.,University Ibn Zohr |
El Kazzouli S.,Euro-Mediterranean University |
Bousmina M.,Euro-Mediterranean University |
Bousmina M.,Hassan II Academy of Science and Technology |
Guillaumet G.,CNRS Institute of Organic and Analytical Chemistry
European Journal of Organic Chemistry | Year: 2014
This review surveys recent developments (reported in the last fifteen years) in organometallic-chemistry-based methods for the functionalization of imidazo[1,2-a]pyridines, in particular the decoration of the pyridine and imidazole rings by means of reactions such as Sonogashira, Heck, Negishi, Suzuki-Miyaura, and Stille cross-coupling, as well as by C-H activation, C-arylation, C-alkenylation, and carbonylation. Results relating to one-pot double functionalization of two different positions on the imidazo[1,2-a] pyridine system are also reviewed. Procedures in which metal-based catalysis is not involved in the functionalization of imidazo[1,2-a]pyridines are not included. Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Hamdani M.,University Ibn Zohr |
Singh R.N.,Banaras Hindu University |
Chartier P.,CNRS Institute of Chemistry
International Journal of Electrochemical Science | Year: 2010
Many spinel cobaltite oxides meet the requirement for a wide range of electrochemical reactions. These materials have largely been investigated as electrocatalysts for the oxygen evolution reaction (OER) or oxygen reduction reaction (ORR). The objective of this article is to summarize the studies available in the literature on electrochemical and electrocatalytic properties of cobaltite spinel oxides towards the OER and ORR in alkaline media. The main focus of this review is on the recent investigations dealing with the performance of Co3O4and Cobased spinel oxides as the oxygen electrodes in the light of the earlier published work. © 2010 by ESG.
Ouadid-Ahidouch H.,University of Picardie Jules Verne |
Dhennin-Duthille I.,University of Picardie Jules Verne |
Gautier M.,University of Picardie Jules Verne |
Sevestre H.,University of Picardie Jules Verne |
And 2 more authors.
Trends in Molecular Medicine | Year: 2013
Breast cancer is the most frequently occurring cancer in women and has the highest rate of mortality. Ion channels such as the transient receptor potential (TRP) channels could play a critical role in the development and progression of cancer. Although these channels are frequently and abundantly expressed in many tumors, their expression, activity, and roles in the context of breast cancer remain poorly understood. This review summarizes our current knowledge regarding TRP channels expressed in human breast tissue, primary human breast epithelial cells, and cell lines, the functional role of TRP channels during breast cancer cell growth and migration, as well as their relationship with clinical and pathological features. © 2012 Elsevier Ltd.
Bnouhachem A.,Nanjing University |
Bnouhachem A.,University Ibn Zohr |
Xu M.H.,Changzhou University
Computers and Mathematics with Applications | Year: 2014
In this paper, we present an inexact alternating direction method. Each iteration of the proposed method contains a prediction and a correction, the predictor is obtained via solving the logarithmic-quadratic proximal (LQP) system approximately under significantly relaxed accuracy criterion and the new iterate is computed directly by an explicit formula derived from the original LQP method. Under certain conditions, the global convergence of the proposed method is proved. © 2013 Elsevier Ltd. All rights reserved.
Nemiche M.,University Ibn Zohr
International Journal of Intelligent Systems | Year: 2016
The Special Issue of International Journal of Intelligent Systems discusses articles from the papers presented at to the Second World Conference on Complex Systems (WCCS), which took place on November 10-12, 2014 in Agadir, Morocco. Lemos and colleagues in the first article 'On legitimacy feedback mechanisms in agent-based modeling of civil violence' extended Epstein's well-known agent-based model of civil violence by introducing endogenous legitimacy feedback, with four different functions for expressing the legitimacy and two feedback mechanisms, homogeneous (global) and heterogeneous (agent dependent). The article 'Accuracy comparison of analogy-based software development effort estimation techniques' by Idri and colleagues. deals with categorical attributes is one of the most difficult issues for analogy-based estimation techniques. The article 'An adaptive regulation approach of mobile agent population size in distributed systems' by Bakhouya and colleagues. deals with the dynamic regulation of agent population size in ubiquitous and pervasive computing systems. The last article 'A comparative study between the dynamic behaviors of standard cellular automata (CA) and network CA applied to cryptography' by MacA○edo and colleagues. presents an extensive experimental study on the relative advantages of a network cellular automata model for cryptographic applications, compared to standard CA.
Ouadid-Ahidouch H.,University of Picardie Jules Verne |
Ahidouch A.,University of Picardie Jules Verne |
Ahidouch A.,University Ibn Zohr
Frontiers in Physiology | Year: 2013
K+ ions play a major role in many cellular processes. The deregulation of K+ signaling is associated with a variety of diseases such as hypertension, atherosclerosis, or diabetes. K+ ions are important for setting the membrane potential, the driving force for Ca2+ influx, and regulate volume of growing cells. Moreover, it is increasingly recognized that K+ channels control cell proliferation through a novel signaling mechanisms triggered and modulated independently of ion fluxes. In cancer, aberrant expression, regulation and/or sublocalization of K+ channels can alter the downstream signals that converge on the cell cycle machinery. Various K+ channels are involved in cell cycle progression and are needed only at particular stages of the cell cycle. Consistent with this idea, the expression of Eag1 and HERG channels fluctuate along the cell cycle. Despite of acquired knowledge, our understanding of K+ channels functioning in cancer cells requires further studies. These include identifying the molecular mechanisms controlling the cell cycle machinery. By understanding how K+ channels regulate cell cycle progression in cancer cells, we will gain insights into how cancer cells subvert the need for K+ signal and its downstream targets to proliferate. © 2013 Ouadid-Ahidouch and Ahidouch.
Allou L.,CNRS The Institute of Chemistry and Processes for Energy, Environment and Health |
El Maimouni L.,University Ibn Zohr |
Le Calve S.,CNRS The Institute of Chemistry and Processes for Energy, Environment and Health
Atmospheric Environment | Year: 2011
Henry's law constants H of formaldehyde and benzaldehyde were determined using a dynamic system based on the water/air equilibrium at the interface within the length of a microporous tube. The measurements were conducted over the range 273-293K in (i) deionized water, (ii) 35gL-1 solution of NaCl simulating seawater and (iii) two nitric acid solutions, i.e. 0.63 and 6.3wt%.In pure water, the obtained data were used to derive the following Arrhenius expressions: lnH=(6423±542)/T-(13.4±2.0) and lnH=(6258±280)/T-(17.5±1.0) for formaldehyde and benzaldehyde, respectively. The H values, calculated at 293K from Arrhenius expressions cited above were the following (in units of Matm-1): H=5020±1170 (formaldehyde), H=47±5 (benzaldehyde). The temperature dependence of H permits then to derive the solvation enthalpies for both compounds: ΔHsolv=-(53.4±4.5)kJmol-1 and ΔHsolv=-(52.0±2.3)kJmol-1 for formaldehyde and benzaldehyde, respectively.In 35gL-1 salt solution, the H values were 27-66% and 12-21% lower than their respective determinations in deionized water, for formaldehyde and benzaldehyde respectively. The observed salt effect was used to estimate the following Setschenow coefficients at 293K for 0.6M NaCl: formaldehyde (0.21) and benzaldehyde (0.09).In 6.3. wt% nitric acid solution, H values of benzaldehyde were approximately 30% higher than those found in pure water although no significant influence was observed for formaldehyde.Finally, our experimental data were then used to estimate the fractions of formaldehyde and benzaldehyde in atmospheric aqueous phase and their derived atmospheric lifetimes. © 2010 Elsevier Ltd.
Salghi R.,University Ibn Zohr |
Armbruster W.,University of Hohenheim |
Schwack W.,University of Hohenheim
Food Chemistry | Year: 2014
Triacylglycerol profiles were selected as indicator of adulteration of argan oils to carry out a rapid screening of samples for the evaluation of authenticity. Triacylglycerols were separated by high-performance liquid chromatography-evaporative light scattering detection. Different peak area ratios were defined to sensitively detect adulteration of argan oil with vegetable oils such as sunflower, soy bean, and olive oil up to the level of 5%. Based on four reference argan oils, mean limits of detection and quantitation were calculated to approximately 0.4% and 1.3%, respectively. Additionally, 19 more argan oil reference samples were analysed by high-performance liquid chromatography-refractive index detection, resulting in highly comparative results. The overall strategy demonstrated a good applicability in practise, and hence a high potential to be transferred to routine laboratories. © 2014 Elsevier B.V. All rights reserved.
Chahid A.,Laboratory Regional Danalyses Et Of Recherche Agadir Office National Of Securite Sanitaire Des Aliments |
Hilali M.,University Ibn Zohr |
Benlhachimi A.,University Ibn Zohr |
Bouzid T.,Laboratory Regional Danalyses Et Of Recherche Agadir Office National Of Securite Sanitaire Des Aliments
Food Chemistry | Year: 2014
As a part of a specific monitoring program, lead (Pb) cadmium (Cd) and mercury (Hg) concentrations in important species of fish from various fishing ports of the southern Kingdom of Morocco (Sardina pilchardus, Scomber scombrus, Plectorhinchus mediterraneus, Trachurus trachurus, Octopus vulgaris, Boops boops, Sarda sarda, Trisopterus capelanus, and Conger conger) were investigated by the Moroccan Reference Laboratory (NRL) for trace elements in foodstuffs of animal origin. The samples were analysed for lead and cadmium by a graphite furnace atomic absorption spectrometry (GFAAS); and for mercury by cold vapour atomic absorption spectrometry (CVAAS). The results were expressed as μg/g of wet weight (w/w). The levels of Cd, Pb and Hg in muscles of fish were 0.009-0.036, 0.013-0.114 and 0.049-0.194 μg/g, respectively. The present study showed that different metals were present in the sample at different levels but within the maximum residual levels prescribed by the EU for the fish and shellfish from these areas, in general, should cause no health problems for consumers. © 2013 Elsevier Ltd. All rights reserved.
El Aimani S.,University Ibn Zohr
Proceedings of the International Conference on Microelectronics, ICM | Year: 2016
This paper presents investigations in the design of wind turbine control systems to maximize the energy capture and their impact onto the grid. The modeling of the wind turbine is presented. Then three different speed control systems are detailed and evaluated through simulations carried out with Matlab Simulink TM. Power fluctuations on the distribution grid are then compared by considering the same wind speed fluctuations. © 2015 IEEE.