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Heberly F.B.,Federal University of Uberlandia | Ferreira I.M.,LABIO FAMEVUFU | Leal G.S.,University Federal Of Goiania | Fonseca B.B.,Federal University of Uberlandia | Rossi D.A.,LABIO FAMEV UFU
Bioscience Journal | Year: 2010

The kibe mass pass to an intensive handling, being exposed to several hazards on microbial contamination opportunities. These contaminations can conduct to product deterioration or offer risks to the costumers' health. The inadequate hygiene conditions and storage emphasize this problematic system. The study aimed to determine the kibe mass contamination by bacterial from thermotolerants coliforms, Staphylococcus positive coagulase andSalmonella spp., of the kibe masses commercialized in five geographic sectors of the Uberlândia-MG; ascertain the suitability of the product's specifications to ANVISA, and the main risks related to contamination by thermotolerant. 42% of the analyzed samples (21/50) were found as unsatisfactory due termotolerant coliforms (38%) above permissible legislation values and Salmonella spp. presence (4%). No samples showed inadequate counting of Staphylococcus positivecoagulase. Risk factors positively related to contamination by fecal coliform were: distribution and organization of food atthe counter refrigerator (P = 0.002, OR = 3.21), hygiene and maintenance of vessels (P = 0.26, OR = 2, 02) and air (P = 0.09, OR = 2.72). None of the risk analysis was directly associated with the presence of Salmonella spp.


Bianco H.T.,Federal University of São Paulo | Izar M.C.,Federal University of São Paulo | Fonseca H.A.,Federal University of São Paulo | Povoa R.M.,Federal University of São Paulo | And 5 more authors.
Arquivos Brasileiros de Cardiologia | Year: 2014

Background: Patients with diabetes are in extract higher risk for fatal cardiovascular events.Objective: To evaluate major predictors of mortality in subjects with type 2 diabetes.Methods: A cohort of 323 individuals with type 2 diabetes from several regions of Brazil was followed for a long period. Baseline electrocardiograms, clinical and laboratory data obtained were used to determine hazard ratios (HR) and confidence interval (CI) related to cardiovascular and total mortality.Results: After 9.2 years of follow-up (median), 33 subjects died (17 from cardiovascular causes). Cardiovascular mortality was associated with male gender; smoking; prior myocardial infarction; long QTc interval; left ventricular hypertrophy; and eGFR <60 mL/min. These factors, in addition to obesity, were predictors of total mortality. Cardiovascular mortality was adjusted for age and gender, but remained associated with: smoking (HR = 3.8; 95% CI 1.3-11.8; p = 0.019); prior myocardial infarction (HR = 8.5; 95% CI 1.8-39.9; p = 0.007); eGFR < 60 mL/min (HR = 9.5; 95% CI 2.7-33.7; p = 0.001); long QTc interval (HR = 5.1; 95% CI 1.7-15.2; p = 0.004); and left ventricular hypertrophy (HR = 3.5; 95% CI 1.3-9.7; p = 0.002). Total mortality was associated with obesity (HR = 2.3; 95% CI 1.1-5.1; p = 0.030); smoking (HR = 2.5; 95% CI 1.0-6.1; p = 0.046); prior myocardial infarction (HR = 3.1; 95% CI 1.4-6.1; p = 0.005), and long QTc interval (HR = 3.1; 95% CI 1.4-6.1; p = 0.017).Conclusions: Biomarkers of simple measurement, particularly those related to target-organ lesions, were predictors of mortality in subjects with type 2 diabetes. © 2014, Arquivos Brasileiros de Cardiologia. All rights reserved.


Fragoso Y.D.,Metropolitan University of Santos | Boggild M.,Walton Center | MacIas-Islas M.A.,University of Guadalajara | Carra A.,Hospital Britanico Of Buenos Aires | And 36 more authors.
Clinical Neurology and Neurosurgery | Year: 2013

Background and objective: Women with multiple sclerosis (MS) who intend to get pregnant are often advised to discontinue disease modifying therapy (DMT) prior to conception. This recommendation is not based on medical evidence and may interfere with disease control by immunomodulatory drugs. The present study was designed to help discuss the effect of DMT for MS on pregnancy and on disease course. Patients and methods: Retrospective data from 152 pregnancies of 132 women with MS were collected by the physician in charge of the case. All data were entered into a specific file for qualitative and quantitative statistical analysis. Results: From the total group of patients, 89 pregnancies occurred without any exposure to MS drugs, while 61 pregnancies occurred with at least eight weeks of exposure to MS immunomodulatory drugs. The rate of obstetric and neonatal complications was similar in both groups, except for the newborn weight and height which was smaller for mothers receiving medications. Mothers' post-delivery relapse rate and EDSS scores in the follow-up period were significantly higher in the absence of treatment. Conclusion: It is possible that, with further such supportive data, international guidelines on MS treatment in young women who intend to get pregnant may need to be revised. © 2012 Elsevier B.V.


Alves J.M.,Instituto Federal Goiano | Leandro W.M.,University Federal Of Goiania | Alves C.C.F.,Instituto Federal Goiano | Carlos L.,Instituto Federal Goiano | And 2 more authors.
Revista Brasileira de Engenharia Agricola e Ambiental | Year: 2016

Crambe has been studied as an option in crop rotation systems in order to provide raw material for biodiesel production. This study aimed to evaluate the effect of raising soil base saturation and addition of phosphorus (P) on the vegetative development, grain yield and oil content of crambe. The experiment was carried out in a Oxisol, arranged in factorial scheme (4 x 3), with 4 replicates (48 plots), in completely randomized blocks. Four base saturation levels (34 - natural of the soil, 40, 50 and 60%) and three P doses (0, 40 and 80 kg ha-1 of P2O5) were evaluated. The experimental plots formed a 9 m2 rectangle with 5 plant rows, spaced by 0.45 m, using the cultivar “Brilliant FMS”. The evaluated variables were: dry matter of roots and shoots at three different times (35, 45 and 55 days after emergence), grain yield and oil content. Base saturation favored crambe root and shoot development, yield and oil content, with the best results for base saturation of 47-48%. The addition of P doses also favored the increase of the analyzed variables. © 2016, Departamento de Engenharia Agricola - UFCG/Cnpq. All rights reserved.


Diculescu V.C.,University of Coimbra | Satana H.E.,University of Coimbra | Satana H.E.,Gazi University | deSouzaGil E.,University of Coimbra | And 2 more authors.
Electroanalysis | Year: 2012

The methoxylation and glycosylation effect on the redox mechanism of citroflavones, isorhoifolin, linarin, diosmetin and diosmin, was investigated. All citroflavones' hydroxyl groups can be electrochemically oxidised, and the oxidation at the B-ring occurs at a lower potential than at the A-ring. The electrochemical oxidation is irreversible, pH-dependent, with occurrence of one or two oxidation products, which undergo reversible redox reactions, depending on the number of OH substituents on the molecule. The glycosylation leads to a steric effect and decreasing of the oxidation peak currents whereas the methylation involves the formation of nonelectroactive oxidation products. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Gomes S.M.C.,University of Coimbra | Ghica M.-E.,University of Coimbra | Rodrigues I.A.,University of Coimbra | Rodrigues I.A.,Federal University of Maranhão | And 3 more authors.
Talanta | Year: 2016

Phenolic compounds detection in fruit extracts from: açai, bacuri, buriti, blackberry, black mulberry, blueberry, juçara, physalis, raspberry, and tamarillo, have been performed by reverse-phase high performance liquid chromatography with electrochemical detection (RP-HPLC-EC), using two detectors in series: a wall-jet detector flow cell with a glassy carbon electrode, and a thin-layer flow cell detector with a boron doped diamond electrode. This methodology, in gradient elution mode, was successfully used to detect seventeen phenolic compounds in the fruit extracts. The total antioxidant capacity of the fruit extracts by the electrochemical quantitative index (EI) and the method of capture of diphenilpicrilhydrazil (DPPH•) free radical "efficient concentration" (EC50), was evaluated. A very good correlation between EI and EC50 assays has been obtained, the fruit with the highest total antioxidant capacity being blackberry, while physalis exhibited the lowest antioxidant power. © 2016 Elsevier B.V. All rights reserved.


Junior J.A.,University Federal Of Goiania | Da Silveira P.M.,University Federal Of Goiania | Stone L.F.,University Federal Of Goiania | da Cunha P.C.R.,University Federal Of Goiania
IRRIGA | Year: 2010

Knowing the amount of water retained by common bean leaves is important for irrigation and chemigation purposes. This study was carried out in order to estimate the volume of water retained in common bean leaves per unit area (ha), under a center pivot irrigation depth. Pérola common bean cultivar was sown in the summer, autumn and winter crop season at 0.45 m between rows and 15 plants per meter. 10 plants were measured at five phenological stages. The amount of water retained in the bean leaves was obtained by the difference between total plant weight (measured after irrigation) and dry plant weight (measured after drying with air). The total plant leaf area was evaluated for each sampling period using a leaf area meter LICOR, model 3100. Data were submitted to regression analyses. Results indicated that the water retained in bean leaves (V, L ha-1) can be estimated using a leaf area index (V=648.12*LAI). The application of average water depth of 8.1 mm allowed 2.5% of average water losses by foliar interception.


Neto V.V.G.,University Federal Of Goiania | Lopes De Oliveira J.,University Federal Of Goiania
Proceedings of the 2011 International Workshop on Early Aspects, EA'11 | Year: 2011

This paper presents preliminary results of application of aspects to address one of the Model-Driven Development (MDD) approach key issues, namely the pluggability principle. According to this principle, a MDD based software solution should provide transformation definition rules that can be plugged into a model-driven transformer to provide automatic mapping between models. We identified the invocation of these transformation rules as a new early aspect for model-driven transformers engineering. This paper presents the main ideas behind this new early aspect, discussing its impact on model-driven transformers engineering.

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