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University College London , formerly styled University College, London, is a public research university in London, England and a constituent college of the federal University of London. Founded in 1826 as London University, UCL was the first university institution established in London and the first in England to be entirely secular, to admit students regardless of their religion, and to admit women on equal terms with men. The philosopher Jeremy Bentham is commonly regarded as the spiritual father of UCL, as his radical ideas on education and society were the inspiration to its founders, although his direct involvement in its foundation was limited. UCL became one of the two founding colleges of the University of London in 1836. It has grown through mergers, including with the Institute of Neurology , the Eastman Dental Institute , the School of Slavonic and East European Studies , the School of Pharmacy and the Institute of Education .UCL's main campus is located in the Bloomsbury area of central London, with a number of institutes and teaching hospitals elsewhere in central London, and satellite campuses in Adelaide, Australia and Doha, Qatar. UCL is organised into 11 constituent faculties, within which there are over 100 departments, institutes and research centres. UCL has around 36,000 students and 11,000 staff and had a total income of £1.02 billion in 2013/14, of which £374.5 million was from research grants and contracts. Measured by number of students it is both the largest higher education institution in London and largest postgraduate institution in the UK. UCL is responsible for several museums and collections in a wide range of fields including the Petrie Museum of Egyptian Archaeology, a leading collection of Egyptian and Sudanese archaeology, and the Grant Museum of Zoology and Comparative Anatomy.UCL ranks highly in domestic and global league tables; it is 20th in the world in the 2014 Academic Ranking of World Universities, joint 5th in the world in the 2014 QS World University Rankings and 22nd in the world in the 2014/15 Times Higher Education World University Rankings. For the period 1999 to 2009 it was the 13th most-cited university in the world . There are 32 Nobel Prize winners and three Fields Medalists amongst UCL's alumni and current and former staff. UCL alumni include the "Father of the Nation" of each of India, Kenya and Mauritius, the inventor of the telephone, and one of the co-discoverers of the structure of DNA. All five of the naturally-occurring noble gases were discovered at UCL by William Ramsay.UCL is part of three of the 11 biomedical research centres established by the NHS in England and is a founding member of the Francis Crick Institute and UCL Partners, the world's largest academic health science centre. UCL has hundreds of research and teaching partnerships, including a major collaboration with Yale University, the Yale UCL Collaborative. UCL is a member of numerous academic organisations including the G5, the League of European Research Universities and the Russell Group and forms part of the 'golden triangle' of British universities. Wikipedia.

Price S.L.,University College London
Chemical Society Reviews | Year: 2014

Currently, organic crystal structure prediction (CSP) methods are based on searching for the most thermodynamically stable crystal structure, making various approximations in evaluating the crystal energy. The most stable (global minimum) structure provides a prediction of an experimental crystal structure. However, depending on the specific molecule, there may be other structures which are very close in energy. In this case, the other structures on the crystal energy landscape may be polymorphs, components of static or dynamic disorder in observed structures, or there may be no route to nucleating and growing these structures. A major reason for performing CSP studies is as a complement to solid form screening to see which alternative packings to the known polymorphs are thermodynamically feasible. This journal is © the Partner Organisations 2014.

A number of autobiographical memory theories and clinical theories of posttraumatic stress disorder (PTSD) make claims that are different from standard views of memory and have been the subject of controversy. These claims include the existence of a long-term perceptual memory system supporting conscious experience separate to episodic memory; greater involvement of perceptual memory in the response to emotion-laden and personally meaningful events; increased perceptual memory intrusions accompanied by impaired episodic memory for the traumatic event among PTSD patients; and a lack of association, or inverse association, between indices of voluntary recall and involuntary images relating to the same traumatic materials. In this article I review current research on perceptual memory, which supports the presence of long-term representations that are selective or incomplete reflections of sensory input. The functional independence of perceptual and episodic memory is illustrated by research on verbal overshadowing but is most clearly exemplified by the strong evidence in favor of enhanced perceptual memory and impaired episodic memory in PTSD. Theoretical predictions concerning the relation between perceptual priming and the development of intrusive images, the effect of verbal versus visuospatial secondary tasks on intrusive trauma images, and the independence of voluntary and involuntary memory for the same materials have garnered widespread support. Reasons for the continuing controversy over traumatic memory are discussed, and some implications of the review for general theories of recall and recognition, clinical theories of PTSD, and "special mechanism" views of memory are set out. © 2014 American Psychological Association.

Buchan D.W.,University College London
Nucleic acids research | Year: 2013

Here, we present the new UCL Bioinformatics Group's PSIPRED Protein Analysis Workbench. The Workbench unites all of our previously available analysis methods into a single web-based framework. The new web portal provides a greatly streamlined user interface with a number of new features to allow users to better explore their results. We offer a number of additional services to enable computationally scalable execution of our prediction methods; these include SOAP and XML-RPC web server access and new HADOOP packages. All software and services are available via the UCL Bioinformatics Group website at http://bioinf.cs.ucl.ac.uk/.

Lloyd A.C.,University College London
Cell | Year: 2013

An adult animal consists of cells of vastly different size and activity, but the regulation of cell size remains poorly understood. Recent studies uncovering some of the signaling pathways important for size/growth control, together with the identification of diseases resulting from aberrations in these pathways, have renewed interest in this field. This Review will discuss our current understanding of how a cell sets its size, how it can adapt its size to a changing environment, and how these processes are relevant to human disease. © 2013 Elsevier Inc.

Marson C.M.,University College London
Chemical Society Reviews | Year: 2012

Reactions in which several components are combined in sequence, and without isolation of intermediates, are greatly sought because of the inherent molecular diversity, efficiency, and atom-economy. However, organocatalytic reactions, employing an organic catalyst to assemble products of high enantiomeric excess (a single optical isomer), are also cutting-edge methodology. This tutorial review covers the overlap of these two areas, outling the structural diversity and stereocontrol arising from one-pot combinations of at least three components, powerful approaches with great potential that minimise formation of by-products and operating costs. This journal is © The Royal Society of Chemistry 2012.

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