University College Dublin - formally known as University College Dublin - National University of Ireland, Dublin is Ireland's largest, and the island of Ireland's second largest, university, with over 1,300 faculty and 17,000 undergraduate students. It is located in Dublin, the Irish capital. Wikipedia.
McGettigan P.A.,University College Dublin
Current Opinion in Chemical Biology | Year: 2013
The transcriptomics field has developed rapidly with the advent of next-generation sequencing technologies. RNA-seq has now displaced microarrays as the preferred method for gene expression profiling.The comprehensive nature of the data generated has been a boon in terms of transcript identification but analysis challenges remain. Key among these problems is the development of suitable expression metrics for expression level comparisons and methods for identification of differentially expressed genes (and exons). Several approaches have been developed but as yet no consensus exists on the best pipeline to use.De novo transcriptome approaches are increasingly viable for organisms lacking a sequenced genome. The reduction in starting RNA required has enabled the development of new applications such as single cell transcriptomics.The emerging picture of mammalian transcription is complex with further refinement expected with the integration of epigenomic data generated by projects such as ENCODE. © 2013 Elsevier Ltd. Source
Albrecht M.,University College Dublin
Chemical Reviews | Year: 2010
A study was conducted some of the fundamental aspects and the latest trends in the field of cyclometalation using d-block transition metals. It was revealed that cyclometalation had emerged as one of the most popular organometallic reactions, providing a simple entry to organometallic compounds. It allowed for the investigation of the essential aspects governing the metal-mediated activation of unreactive bonds, such as the C-H bond. The study covered seminal fundamental literature and the latest highlights and the trends that emerged till early 2009. Cyclometalation gained significance due to the reaction representing the mildest route for achieving strong C-H and C-R bonds. It had also emerged as an attractive and versatile synthetic method for creating organometallic entities with significantly wide application potential. Source
Braun H.-B.,University College Dublin
Advances in Physics | Year: 2012
Micromagnetics has been the method of choice to interpret experimental data in the area of microscopic magnetism for several decades. In this article, we show how progress has been made to extend this formalism to include thermal and quantum fluctuations in order to describe recent experimental developments in nanoscale magnetism. For experimental systems with constrained dimensions such as nanodots, atomic chains, nanowires, and thin films, topological defects such as solitons, vortices, skyrmions, and monopoles start to play an increasingly important role, all forming novel types of quasiparticles in patterned low-dimensional magnetic systems. We discuss in detail how soliton-antisoliton pairs of opposite chirality form non-uniform energy barriers against thermal fluctuations in nanowires or pillars. As a consequence of their low barrier energy compared to uniform reversal, they limit the thermal stability of perpendicular recording media. For sufficiently short samples, the non-uniform energy barrier continuously merges into the conventional uniform Néel-Brown barrier. Partial formation of chiral domain walls also determines the magnetic properties of granular nanostructured magnets and exchange spring systems. For a long time, the reconciliation between micromagnetics and quantum mechanics has remained an unresolved challenge. Here it is demonstrated how inclusion of Berry's phase in a micromagnetic action allows for a semiclassical quantization of spin systems, a method that is demonstrated by the simple example of an easy-plane spin. This powerful method allows for a description of quantum dynamics of solitons and breathers which in the latter case agrees with the anisotropic spin-XYZ-model. The domain wall or soliton chirality plays an important role as it is coupled to the wavevector of the quasiparticle dispersion. We show how this quantum soliton chirality is detected by polarized neutron scattering in one-dimensional quantum antiferromagnets. © 2012 Taylor & Francis. Source
University College Dublin | Date: 2015-10-13
A system for applying indicia to food products comprises a dispenser for successively dispensing a quantity of food paste onto a respective surface of a portion of food. The food paste comprises a carrier, a setting agent and a contrasting agent. A fusing unit fuses a dispensed portion of the paste to provide at least one solid indicium on the food product, the indicium optically contrasting with the portion of food.
University College Dublin | Date: 2014-05-23
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