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Campobasso, Italy

MacChia G.,University Cattolica Largo A | Morganti A.G.,University Cattolica Largo A | Morganti A.G.,University Cattolica | Cilla S.,University Cattolica | And 13 more authors.
Cancer Investigation | Year: 2012

Aim: To analyze the results of extracranial stereotactic radiotherapy (ESRT) experience in pancreatic cancer patients. Methods: Four noncoplanar fixed beams were used in all patients. Results: Analysis of 16 patients was carried out. Overall response rate was 56.2%. Fifteen patients experienced local and/or distant progression of disease (median follow-up: 24 months). Two-year local progression-free, distant progression-free, and overall survivals were 85.7%, 58.7%, and 50.0%, respectively. Toxicity was less than grade 2 in all, although 1 patient had severe duodenal bleeding. Quality of life scores were unchanged. Conclusions: ESRT was associated with low complication rate, and not worsening the patients' quality of life. © 2012 Informa Healthcare USA, Inc. Source

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