Iaşi, Romania
Iaşi, Romania

Time filter

Source Type

Ioan C.C.,Technical University Gheorghe Asachi | Ursu C.,Apollonia University
Environmental Engineering and Management Journal | Year: 2010

Noise is probably the polluting factor which induces the most commonly risk encountered at workplace, where millions of people are exposed to potentially harmful noise levels, but also in the environment. The degree of noise tolerance of the human ear before the installation of deafness cannot be measured directly, but it can be assessed as a vulnerability that signals the onset of ear fatigue. Ear fatigue induces mental fatigue and triggers the decrease in work efficiency and thus indirectly affects the quality of life. The aim of our study is to examine to what extent the professional performance in a noise-polluted environment is influenced by the installation of mental fatigue as a direct consequence of the auditory one.


Ioan C.C.,Technical University Gheorghe Asachi | Ursu C.,Apollonia University
Environmental Engineering and Management Journal | Year: 2012

Quality of life, which has been assessed by measuring the degree to which objective human needs are met in relation to personal or group perceptions, has been largely investigated over the years. In this direction, various methods and techniques have been employed in order to determine the most effective criteria and indicators of obtaining adequate residential or work spaces. It can be said that one of the priorities of a "healthy" building is to comply with health and comfort criteria. Various organizations all over the world consider that the built environment is characterized by a number of parameters which might threaten human health. The effects upon human health of the time spent in a building could not be entirely explained. The performance indicators used nowadays are not enough to perform a correct assessment and many times the current standards differ greatly from the needs of those who work in these spaces. Taking into consideration the fact that urban society spends more and more time indoors, indoor air quality has become an important public health problem at global scale. Besides the benefits of comfort it brings, air conditioning can affect human health, because it greatly modifies the environment in which the individual is placed. The strategies employed to ameliorate the conditions offered by modern buildings imply measures related to the indoor environment and also to the building itself. Preventive methods for maintaining a sustainable quality of life in an air conditioned environment address the human factor and imply a close medical evaluation of candidate employees, in order to avoid the occurrence of some disorders in those people who are prone to illnesses determined by this type of environment according to their personal or family medical history, or the decompensation of already existing illnesses.


Ioan C.C.,Technical University Gheorghe Asachi | Ursu C.,Apollonia University
Environmental Engineering and Management Journal | Year: 2011

Engineers posses the skill of making the life more comfortable, by using new technologies that may have damaging, unpredictable, unintentional effects, which sometimes occur because of malpractice. Thus, a question arises: to what extent could engineers be responsible for their work? It is common knowledge that every technology has tardy, indirect effects upon plants, animals, ecosystems and future generations. This issue is directly linked to professional ethics. Engineering ethics includes compulsory moral behaviour standards and it contains a particular kind of principles. Further on, there are supplementary elements (impartiality, honesty, integrity) that lead to a set of special behaviour standards, which constitute engineering ethics and can be found in a code of ethics. When do future Romanian engineers find out about their professional responsibilities and the issues of moral demeanour, which often occur in their activity? After they graduate! The importance of introducing ethics in the technical education syllabus is undeniable, taking into consideration the fact that engineers are expected to reach the highest standards of honesty and integrity, especially because their actions have a vital, direct impact upon the quality of life!


PubMed | th Military Support Unit, University of Medicine and Pharmacy of Targu Mures, Apollonia University and University Of Medicine And Pharmacy Gr pa Iasi
Type: Journal Article | Journal: The Journal of dermatological treatment | Year: 2016

The current use of tumor necrosis factor (TNF)-alpha inhibitors in rheumatological, dermatological and gastroenterological diseases has increased considerably in recent years. Different reports have been communicated regarding specific risks and side effects during treatment with TNF-alpha inhibitors. Eosinophilia has been linked to TNF-alpha inhibitors by several recent reports, although it is not listed as a possible adverse reaction in the product information of the drug. The aim of the present study was to evaluate the eosinophil count in patients diagnosed with psoriasis and treated with adalimumab. Based on the results of the present study, eosinophilia remains a rare adverse reaction during psoriasis treatment with TNF-alpha antagonists.


Chiriac A.,Apollonia University | Chiriac A.,Nicolina Medical Center | Chiriac A.,Pponi Institute Of Macromolecular Chemical | Brzezinski P.,th Military Support Unit | And 2 more authors.
Clinical Interventions in Aging | Year: 2015

Green nails, also known as chloronychia or green nail syndrome, are characterized by green discoloration of the nail plate (greenish-yellow, greenish-brown, greenish-black), proximal chronic non-tender paronychia, and distolateral onycholysis. The cause is Pseudomonas aeruginosa infection of the nail plate in persons whose hands are constantly exposed to water, soaps, and detergents or are subject to mechanical trauma, especially in the elderly. Green or black coloration of the nails should raise suspicion for Pseudomonas infection and be treated with an oral quinolone (ciprofloxacin), particularly in aged patients. We present three cases of green nails in elderly persons. © 2015 Chiriac et al.


Sinitchi G.,Apollonia University | Costin D.,Grigore T. Popa University of Medicine and Pharmacy | Diaconescu S.,Grigore T. Popa University of Medicine and Pharmacy
2015 E-Health and Bioengineering Conference, EHB 2015 | Year: 2015

Contact dermatitis produced by Nickel can be found in adults and elders as in children. Our study included a number of 36 children that came for clinical manifestations of contact dermatitis. The diagnosis was sustained on the base of: case history, clinical examination and the eliminatory test lead to confirmation. Nickel sensitization mentioned in the anamnesis data and in the clinical examination was confirmed by cutaneous Nickel patch tests. We mention the importance of the hereditary factor, children being atopical in percentage of 80%. Avoiding Nickel contact along with antiallergic and immunomulator treatment have led to the improvement of manifestations. Nickel is a frequent cause of allergy. Our study has confirmed the good response of contact dermatitis to the removal of the causing factor and specific antiallergic treatment. Education of the family and child is necessary. © 2015 IEEE.


Zbancioc A.M.V.,Grtpopa University Of Medicine And Pharmacy | Zbancioc G.N.,Al. I. Cuza University | Tanase C.,Al. I. Cuza University | Miron A.,Grtpopa University Of Medicine And Pharmacy | And 2 more authors.
Letters in Drug Design and Discovery | Year: 2010

The emphasis of this work was to design and synthetize a new class of bifunctional DNA intercalators, containing in the same molecule an alkylating part and a nitrogen heterocycles intercalator unit. The adopted strategy is general, straightforward, and only involves two steps: acylation and quaternization. An alternative, fast, general, and environmentally friendly method for preparation of these compounds under microwave (MW) irradiation is also presented. The structure of compounds was proven by elemental (C, H, N) and spectral analysis (IR, 1H NMR, 13C NMR, COSY, HMQC, HMBC). The obtained compounds proved to have excellent anticancer activity in vitro. Possible mechanisms of action and structure-activity relationships are discussed. © 2010 Bentham Science Publishers Ltd.


Buruiana T.,Petru Poni Institute of Macromolecular Chemistry | Melinte V.,Petru Poni Institute of Macromolecular Chemistry | Costin G.,Apollonia University | Buruiana E.C.,Petru Poni Institute of Macromolecular Chemistry
Journal of Polymer Science, Part A: Polymer Chemistry | Year: 2011

Three novel liquid crystalline methacrylates have been synthesized and characterized to be tested as comonomers in light-curing dental resin-based composites. The selected formulations consist of an alkylammonium or cholesteryl urethane methacrylate and 2,2-bis[4-(2-hydroxy-3-methacryloyloxypropyl)phenyl] propane (BisGMA) or a BisGMA derivate modified with urethane methacrylate groups, further diluted with triethyleneglycol dimethacrylate (TEGDMA) and reinforced with 70% filler (zirconium silicate nanopowder, silanized filler). This study addresses the relationships between the LC monomer structure, photopolymerization rates (by differential scanning photo calorimetry), and specific properties of the dental resin composites (volumetric shrinkage, water sorption, water solubility, and hydrophobicity). The investigation of LC properties by differential scanning calorimetry and polarizing microscopy indicated that the LC mesophase is stable to room temperature (cationic monomers) or at 40 °C (cholesteryl methacrylate). It was found that the polymerization rate for LC urethane methacrylates used in combination with BisGMA/TEGDMA (0.122-0.136 s-1) is higher than that of the mesogenic monomers alone (0.085-0.107 s-1). The structures of the urethane monomers and, consequently, the viscosity of the comonomer mixture influence both the rate and the degree of conversion (44.8-67.5 %) of the photopolymerization process. Polymerization shrinkage measured by pycnometry showed lower values for LC monomers (3.25-3.43 vol %) comparatively with the monomer mixture (5.19-6.65 vol %). Preliminarily, the effect of ammonium groups from two resin composites incorporating alkylammonium structures (4.5 wt %) was tested on Streptococcus mutans, and distinct zone of inhibition was observed. © 2011 Wiley Periodicals, Inc.


PubMed | University of Medicine and Pharmacy of Targu Mures, Grigore T. Popa University of Medicine and Pharmacy and Apollonia University
Type: | Journal: The Journal of emergency medicine | Year: 2016

Despite the widespread use of oral or topical acyclovir, allergic contact dermatitis caused by it has been rarely reported, with fewer than 20 case studies published in the English literature to date.A diagnosis of allergic contact dermatitis from acyclovir cream was established in a 62-year-old female patient who had been continuously using acyclovir cream for 3weeks after systemic therapy for herpes zoster with acyclovir, and in a 35-year-old female patient, who had undergone liver transplantation in 2008 and subsequently developed a severe form of herpes zoster treated orally with 4g/day acyclovir and prolonged topical administration of acyclovir cream. In both cases, patch tests were performed with extended European Baseline Series, with the excipients of acyclovir cream (propylene glycol, sodium lauryl sulfate, cetostearyl alcohol, dimethyl sulfoxide) and commercial cream containing acyclovir 2%. Positive reactions were obtained only with the commercial cream with acyclovir 2%. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Allergic contact dermatitis caused by acyclovir is rarely reported and frequently misdiagnosed, despite the wide use of oral or topical acyclovir. Allergic contact dermatitis due to acyclovir applied topically is a clinical problem with which health care providers should be familiar, and which prompts patch testing in suspected patients. Knowledge and education focused on allergens are important to clinicians in daily practice.


PubMed | University of Medicine and Pharmacy of Targu Mures and Apollonia University
Type: Case Reports | Journal: International wound journal | Year: 2016

We present the case of a 54-year-old patient with a thermal cement burn. This rare case is a localised occupational chemical cement burn on the lower limbs, with no systemic involvement and favourable outcome. The lesion was induced by prolonged contact of the skin with cement and water during hot summer days.

Loading Apollonia University collaborators
Loading Apollonia University collaborators