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Iaşi, Romania

Chiriac A.,University Apollonia | Ferariu D.,Grigore T. Popa University of Medicine and Pharmacy | Solovan C.,Victor Babes University of Medicine and Pharmacy Timisoara | Brzezinski P.,th Military Support Unit | Feldman S.R.,Center for Dermatology Research
Dermatology Online Journal | Year: 2014

A 67 year-old man was diagnosed 10 years ago with severe plaque psoriasis and was hospitalized for re-evaluation of therapy. He was treated previously with topical corticosteroids, methotrexate, and phototherapy. As part of the assessment protocol for initiation of biological treatment, a tuberculin skin test was done, which was positive without signs of active tuberculosis. Isoniazid therapy was started with marked improvement of psoriatic lesions before biologic treatment could be initiated. © 2014 by the article author(s).

Brzezinski P.,th Military Support Unit | Chiriac A.E.,Grigore T. Popa University of Medicine and Pharmacy | Pinteala T.,Grigore T. Popa University of Medicine and Pharmacy | Foia L.,Grigore T. Popa University of Medicine and Pharmacy | Chiriac A.,University Apollonia
Pakistan Journal of Medical Sciences | Year: 2015

We present a diabetic patient with associated two diabetic dermatoses: diabetic dermopathy (“shin spots”) and diabetic bullae. A 34-year-old man, with long history of diabetes mellitus, hypertension, and moderate obesity presented to Dermatology Unit for diagnosis of his skin lesions. On clinical examination multiple, light brown, irregular patches, with atrophic scars and crusts over large bullae were observed on the anterior aspect of both legs. © 2015, Professional Medical Publications, All Rights Reserved.

Barbinta A.C.,Technical University Gheorghe Asachi | Earar K.,University Apollonia | Crimu C.-I.,Technical University Gheorghe Asachi | Dragan L.-A.,Technical University Gheorghe Asachi | Munteanu C.,Technical University Gheorghe Asachi
Key Engineering Materials | Year: 2014

Titanium alloys are widely used in medical applications, due to their good mechanical properties, high corrosion resistance and biocompatibility. The aim of this paper was to investigate the cytotoxicity of novel titanium alloys: Ti21Nb6Zr15Ta, Ti25Nb10Zr8Ta, Ti17Nb5Zr5Al, Ti7Nb7Zr2Al with fibroblast-like cells derived from human osteosarcoma cell line (HOS). The results were compared with that of conventional biomedical alloys, like Ti6Al7Nb and Ti6Al4V. In vitro citotoxicity of titanium alloys was evaluated by fluorescence microscopy and MTT colorimetric assay. The results showed that the materials analyzed had no cytotoxic effects on HOS fibroblast-like cells, permitting their attachment and proliferation. Also the new titanium alloys present a higher cell viability than that of the conventional alloys. As a consequence, the TiNbZrTa and TiNbZrAl alloys can be considered as potential candidates for biomedical applications. © (2014) Trans Tech Publications, Switzerland.

Istrate B.,Technical University Gheorghe Asachi | Munteanu C.,Technical University Gheorghe Asachi | Luca D.,Technical University Gheorghe Asachi | Kamel E.,University Apollonia | And 2 more authors.
Key Engineering Materials | Year: 2014

The use of titanium and its alloys is currently considered very attractive for dental implants, with the improvement of physical properties, corrosion resistance and biocompatibility of them. These properties are attributed to the formation of titanium dioxide (TiO2) as a protective layer. The aim of this work is to understand the influence of time on heat treatment of CP-Ti Grade II at 850 °C. Heat treatments were performed for 5, 15, 30, 60 and 120 minutes. The response of titanium to oxidation at same temperatures and various timings has been investigated, in terms of wear resistance, surface morphology and oxide layer substrate adhesion. A variety of experimental and analytical techniques including scanning electron microscopy (SEM) and tribological testing have been used to characterize the resultant thermal oxidized surfaces. The results showed that oxygen diffused Ti structure can produce compact layer (TiO2), which exhibited good adhesion with the substrate at 30 minutes and 120 minutes of heat treatment. © (2014) Trans Tech Publications, Switzerland.

Sachelarie L.,Apollonia University Iasi | Dartu L.,Apollonia University Iasi | Vasiliu M.,University Apollonia | Daraba O.,Apollonia University | And 3 more authors.
Osteoporosis International | Year: 2016

Summary: What are the specific parameters of dental health that present with modifications in osteoporosis (OP)? Both OP and a decreased bone mass can affect dental health. A low mineral density may lead to the loss of dentures because the jaw is exposed to the effects of periodontitis and without strong sustainability the teeth may lose their stability. Introduction: We compared the values of the periodontal index (IP) with a T score for women presenting with OP at menopause and those without OP. We found that there is a relation between OP and the loss of bone mass at the oral-facial level. Methods: The study included 87 patients, aged between 35 and 75 years. We correlated gums and IP with the T score for the two groups. Results: We found a significant difference between the values of the IP index for the group with OP in comparison with the control group. Thus a correlation between OP and IP was confirmed. Conclusions: IP was statistically significantly higher in women at menopause with OP than those without OP. Gum retraction was significantly higher in women at menopause with OP than in the control group. There was thus a real correlation between bone mineral density (BMD) and IP, while between BMD and dental mobility we found no correlation. © 2015, International Osteoporosis Foundation and National Osteoporosis Foundation.

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