Huixquilucan, Mexico
Huixquilucan, Mexico

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Lobaina A.L.,University Anahuac
2015 International Conference on Computing Systems and Telematics, ICCSAT 2015 | Year: 2015

Communications and transmissions tend increasingly to be digital, because of this television signals are leaving transmit with analog standards. For this reason, it is important to teach and analyze the necessary information to implement the Digital Terrestrial Television (DTT). In this case we are going to focus on the ATSC (Advance Television System Committee) standard, which is what Mexico has adopted. The aim of this article is to present a new method of practical teaching for the Radio-communication area in general and particularly the matter "Digital Television" so the student can understand and analyze the different stages of coding, modulation, transmission and reception of the Digital Terrestrial Television (DTT) through Software Defined Radio (SDR). To develop Software Defined Radio (SDR) and follow the trend towards digital transmissions, there are some devices that implement various communication protocols, including UMTS, GSM, WIFI, Bluetooth, etc. With this we have been developed projects of free software such as GNU Radio and USRP software. GNU Radio can operate as a Simulator or with the computer sound card. © 2015 IEEE.


PubMed | University Anahuac, National Autonomous University of Mexico, University of Chile, Austral University of Chile and 2 more.
Type: Journal Article | Journal: The journal of the American College of Clinical Wound Specialists | Year: 2017

The incidence of ulcers associated to type 2 diabetes mellitus (T2DM) increases every year. We introduce and explore a new mathematical algorithm to evaluate wound-healing in foot ulcers associated to T2DM. Fifteen patients (nine women and six men), mean age of 7016 years were included. The evolution of their wounds followed-up for a period of 18-45 days. According to the Wagner grading system the ulcers were grade I (5 patients), grade II (9 patients), and grade III (1 patient). Clinically, the type of the ulcers was neuroischemic (12 patients) and neuropathic (3 patients). A new parameter is introduced, the continuous linear healing rate Dc that was more accurate with higher values and requires less quantifications than usual formulas to make a wound-healing projection.


Polanco C.,University Anahuac | Polanco C.,National Autonomous University of Mexico | Samaniego J.L.,University Anahuac | Samaniego J.L.,National Autonomous University of Mexico | And 2 more authors.
Cell Biochemistry and Biophysics | Year: 2014

Diseases of viral origin in humans are among the most serious threats to health and the global economy. As recent history has shown the virus has a high pandemic potential, among other reasons, due to its ability to spread by air, hence the identification, investigation, containment, and treatment of viral diseases should be considered of paramount importance. In this sense, the bioinformatics research has focused on finding fast and efficient algorithms that can identify highly toxic antiviral peptides and to serve as a first filter, so that trials in the laboratory are substantially reduced. The work presented here contributes to this effort through the use of an algorithm already published by this team, called polarity index method, which identifies with high efficiency antiviral peptides from the exhaustive analysis of the polar profile, using the linear sequence of the peptide. The test carried out included all peptides in APD2 Database and 60 antiviral peptides identified by Kumar and co-workers (Nucleic Acids Res 40:W199–204, 2012), to build its AVPpred algorithm. The validity of the method was focused on its discriminating capacity so we included the 15 sub-classifications of both Databases. © 2014, Springer Science+Business Media New York.


Polanco C.,University Anahuac | Polanco C.,Autonomous University of the State of Morelos | Buhse T.,Autonomous University of the State of Morelos | Samaniego J.L.,University Anahuac | Gonzalez J.A.C.,University Anahuac
Acta Biochimica Polonica | Year: 2013

This paper presents a mathematical-computational toy model based on the assumed dynamic principles of prebiotic peptide evolution. Starting from a pool of amino acid monomers, the model describes in a generalized manner the generation of peptides and their sequential information. The model integrates the intrinsic and dynamic key elements of the initiation of biopolymerization, such as the relative amino acid abundances and polarities, as well as the oligomer reversibility, i.e. fragmentation and recombination, and peptide self-replication. Our modeling results suggest that the relative amino acid abundances, as indicated by Miller-Urey type electric discharge experiments, played a principal role in the early sequential information of peptide profiles. Moreover, the computed profiles display an astonishing similarity to peptide profiles observed in so-called biological common ancestors found in the following three microorganisms; E. coli, M. jannaschii, and S. cereviasiae. The prebiotic peptide fingerprint was obtained by the so-called polarity index method that was earlier reported as a tool for the identification of cationic amphipathic antibacterial short peptides.


Polanco C.,University Anahuac | Buhse T.,Autonomous University of the State of Morelos | Samaniego J.L.,University Anahuac | Castanon-Gonzalez J.A.,University Anahuac
Acta Biochimica Polonica | Year: 2013

Antimicrobial peptides occupy a prominent place in the production of pharmaceuticals, because of their effective contribution to the protection of the immune system against almost all types of pathogens. These peptides are thoroughly studiedby computational methods designed to shed light on their main functions. In this paper, we propose a computational approach, named the Polarity Profile method that represents an improvement to the former Polarity Index method. The Polarity Profile method is very effective in detecting the subgroup of antibacterial peptides called selective cationic amphipathic antibacterial peptides (SCAAP) that show high toxicity towards bacterial membranes and exhibit almost zero toxicity towards mammalian cells. Our study was restricted to the peptides listed in the antimicrobial peptides database (APD2) of December 19, 2012. Performance of the Polarity Profile method is demonstrated through a comparison to the former Polarity Index method byusing the same sets of peptides. The efficiency of the Polarity Profile method exceeds 85% taking into account the false positive and/or false negative peptides.


Figueroa-Lara A.,Security Innovation | Gonzalez-Block M.A.,University Anahuac | Alarcon-Irigoyen J.,Health Policy and Program Design
PLoS ONE | Year: 2016

Background: Chronic diseases (CD) are a public health emergency in Mexico. Despite concern regarding the financial burden of CDs in the country, economic studies have focused only on diabetes, hypertension, and cancer. Furthermore, these estimated financial burdens were based on hypothetical epidemiology models or ideal healthcare scenarios. The present study estimates the annual expenditure per patient and the financial burden for the nine most prevalent CDs, excluding cancer, for each of the two largest public health providers in the country: the Ministry of Health (MoH) and the Mexican Institute of Social Security (IMSS). Methods: Using the Mexican National Health and Nutrition Survey 2012 (ENSANUT) as the main source of data, health services consumption related to CDs was obtained from patient reports. Unit costs for each provided health service (e.g. consultation, drugs, hospitalization) were obtained from official reports. Prevalence data was obtained from the published literature. Annual expenditure due to health services consumption was calculated by multiplying the quantity of services consumed by the unit cost of each health service. Results: The most expensive CD in both health institutions was chronic kidney disease (CKD), with an annual unit cost for MoH per patient of US$ 8,966 while for IMSS the expenditure was US$ 9,091. Four CDs (CKD, arterial hypertension, type 2 diabetes, and chronic ischemic heart disease) accounted for 88% of the total CDs financial burden (US$ 1.42 billion) in MoH and 85% (US$ 3.96 billion) in IMSS. The financial burden of the nine CDs analyzed represents 8% and 25% of the total annual MoH and IMSS health expenditure, respectively. Conclusions/Significance: The financial burden from the nine most prevalent CDs, excluding cancer, is already high in Mexico. This finding by itself argues for the need to improve health promotion and disease detection, diagnosis, and treatment to ensure CD primary and secondary prevention. If the status quo remains, the financial burden could be higher. © 2016 Figueroa-Lara et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Zevallos H.B.-V.,University of Sydney | Zevallos H.B.-V.,University Anahuac | Mckinnon B.,University of Bern | Tokushige N.,University of Sydney | And 3 more authors.
Archives of Gynecology and Obstetrics | Year: 2015

Purpose To assess endometrial gene as well as protein expression of neuroendocrine and supposedly endometriosis- associated product PGP9.5 and pain symptoms in women with endometriosis and controls undergoing laparoscopy, using molecular biological and immuno-histochemical approaches in the same patients. Methods Biopsy of eutopic endometrium from 29 patients by sharp curettage, and preparation of paraffin blocks. Determination of PGP9.5 gene expression and protein abundance using qPCR and immuno-histochemistry. Results qPCR; The PGP9.5 mRNA expression level between women with (N = 16) and without (N = 13) endometriosis was not different, regardless of pain symptoms or menstrual cycle phase. PGP9.5 expression was higher in women who reported pain compared to those who did not; however, this association was not statistically significant. The expression of PGP9.5 mRNA was higher in women with endometriosis and pain during the proliferative than in the secretory phase (P = 0.03). Furthermore, in the first half of the cycle, the abundance of the PGP9.5 transcript was also significantly higher in endometriosis patients compared to those without (P = 0.03). Immunohistochemistry; Thirteen of the 16 endometriosis patients showed positive PGP9.5 immuno-reactivity in the endometrium, whereas no such signal was observed in women without endometriosis. The absolute number of nerve fibres per mm2 in women with endometriosis was similar, regardless of the pain symptoms. Conclusions PGP9.5 mRNA expression is increased in the proliferative phase of endometriotic women with pain. The presence of nerve fibres was demonstrated by a PGP9.5 protein signal in immuno-histochemistry and restricted to patients with endometriosis. Based on these results, however, there did not appear to be a direct association between the gene expression and protein abundance in women with and without endometriosis or those that experienced pain. © Springer-Verlag Berlin Heidelberg 2014.


Garcia E.,University Anahuac | Aguilar-Cevallos J.,University Anahuac | Silva-Garcia R.,Hospital Of Pediatria | Ibarra A.,University Anahuac
Mediators of Inflammation | Year: 2016

Spinal cord injury results in a life-disrupting series of deleterious interconnected mechanisms encompassed by the primary and secondary injury. These events are mediated by the upregulation of genes with roles in inflammation, transcription, and signaling proteins. In particular, cytokines and growth factors are signaling proteins that have important roles in the pathophysiology of SCI. The balance between the proinflammatory and anti-inflammatory effects of these molecules plays a critical role in the progression and outcome of the lesion. The excessive inflammatory Th1 and Th17 phenotypes observed after SCI tilt the scale towards a proinflammatory environment, which exacerbates the deleterious mechanisms present after the injury. These mechanisms include the disruption of the spinal cord blood barrier, edema and ion imbalance, in particular intracellular calcium and sodium concentrations, glutamate excitotoxicity, free radicals, and the inflammatory response contributing to the neurodegenerative process which is characterized by demyelination and apoptosis of neuronal tissue. © 2016 Elisa Garcia et al.


Weber Sanchez A.,University Anahuac
Gaceta Mexicana de Oncologia | Year: 2016

Understanding the ethical nature of informed consent enhances the quality of care, improves the physician-patient relationship, and clinical practice, especially in Oncology.To appreciate patients as individuals and respect their essence as a unique living being endowed with intelligence and free will, a fact that gives them dignity, is essential to this process. This entails responsibilities for both the doctor and the patient in a respectful partnership based on confidence, which has the informed consent as one of its highlights, understood as the free acceptance of a patient to decide about a therapeutic or diagnostic procedure, after being informed of it by the physician. This goes beyond recognising patient freedom to accept medical treatment, and is a giant step in the evolution of the relationship between them that transcends and surpasses old visions.This review is about historical and legal aspects, and a reflection about why and how to perform this part of the clinical process as a continuous dialogue between physician and patient, which is definitely an art that must be cultivated and contributes to the ethics of the informed consent within the special challenges of Oncology. © 2016 Sociedad Mexicana de Oncología.


Fermon S.,University Anahuac | Zaga I.H.,University Anahuac | Alvarez Melloni D.,University Anahuac
Archivos de la Sociedad Espanola de Oftalmologia | Year: 2015

Objective To describe the results of the meibomian gland probing as a treatment of severe posterior blepharitis. Methods Prospective, longitudinal study of patients with signs and symptoms of severe posterior blepharitis, who were treated with meibomian gland probing in Centro Oftalmológico Interlomas (CENOFI). A total of 16 patients were included, 62.5% female and 32.5% male, diagnosed with severe posterior blepharitis. Treatment was performed in one eye. The time of rupture of the tear film was evaluated, using a subjective scale of 0-10 photophobia, the improvement in pain and visual acuity was measured before the procedure, and at one week and 6 months after. Results All the patients showed a statistically significant improvement in all 4 variables al 6 months. There were no complications. Discussion The dysfunction of the meibomian glands is a common reason for ophthalmology consulting. The study describes the results obtained by performing an intraductal survey, which was shown to be safe and effective in 100% of the sample. Conclusions It can be concluded from this study that meibomian gland probing is an effective and promising treatment for blepharitis resistant to conservative treatment. © 2013 Sociedad Española de Oftalmología. Published by Elsevier España, S.L.U. All rights reserved.

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