Kornacka A.,University Medyczny znaniu |
Schroeder G.,University Adama Mickiewicza znaniu |
Eitner K.,University Adama Mickiewicza znaniu |
Szczapa J.,University Medyczny znaniu |
Puchalska M.,Ginekologicznio Polozniczy Szpital Kliniczny
Pediatria Polska | Year: 2012
Introduction: Systemic inflammatory response in neonates with sepsis causes an increase in free oxygen radicals production. Those products can easily react in cells with structural and enzymatic proteins, DNA and lipids of cell membrane. In this way they lead the cell to death. The aim of the study: Evaluation of influence of melatonin on antioxidant processes in preterm newborns with sepsis. Material and method: Twenty preterm newborns were included to the study: 10 with diagnosed sepsis (study group) and 10 without infection (control group). Newborns in study group were treated using melatonin or placebo. Blood samples were collected three times: in a study and in a control group before treatment (zero sample); and in a study group 1 hour after treatment (first sample) and three hours after treatment (second sample). In collected blood samples we measured malondialdehyde concentration and total antioxidant status by using OxisResearch reagents. We also monitored laboratory markers of infection. Results: We observed statistically important reduction of C reactive protein in group of newborns with sepsis treated with melatonin. Total antioxidant status didn't differ statistically between groups. We observed increase of TAS in newborns with sepsis in blood sample collected 1 hour after giving melatonin, but it wasn't statistically important. In all collected blood samples we didn't find malondialdehyde. Conclusion: There is no influence of melatonin treatment on total antioxidant status in preterm newborns with sepsis. Using melatonin in treatment of sepsis required further investigations. © 2012 Polish Pediatric Society.
Prochwicz K.,Instytut Psychologii UJ |
Sobczyk A.,University Adama Mickiewicza znaniu
Psychiatria Polska | Year: 2011
Dancing mania is a clinical and cultural phenomenon which occurred in Western Europe between 13th and 18th centuries. The term dancing mania is derived from the Greek words choros, a dance, and mania, a madness. An Italian variant was known as tarantism as victims were believed to have been bitten by tarantula spider. Although symptoms of dancing manias were well documented in contemporary writings the exact aetiology of dancing plaques is still unclear. Several causes for dancing mania have been postulated: demonic possession, the bite of tarantula, ergot poisoning, epilepsy, mass hysterias, exotics religious cults. The article contains a review of hypothesis of epidemic dances included both medical and psychological factors.