Louvain-la-Neuve, Belgium
Louvain-la-Neuve, Belgium

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Satyanarayana B.,Roosevelt University | Satyanarayana B.,Vrije Universiteit Brussel | Satyanarayana B.,University of Malaysia, Terengganu | Bhanderi P.,Vrije Universiteit Brussel | And 11 more authors.
Ambio | Year: 2012

Although mangroves dominated by Avicennia germinans and Rhizophora mangle are extending over 6000 ha in the Tanbi Wetland National Park (TWNP) (The Gambia), their importance for local populations (both periurban and urban) is not well documented. For the first time, this study evaluates the different mangrove resources in and around Banjul (i.e., timber, non-timber, edible, and ethnomedicinal products) and their utilization patterns, including the possibility of ecotourism development. The questionnaire-based results have indicated that more than 80% of peri-urban population rely on mangroves for timber and non-timber products and consider them as very important for their livelihoods. However, at the same time, urban households demonstrate limited knowledge on mangrove species and their ecological/economic benefits. Among others, fishing (including the oyster-Crassostrea cf. gasar collection) and tourism are the major incomegenerating activities found in the TWNP. The age-old practices of agriculture in some parts of the TWNP are due to scarcity of land available for agriculture, increased family size, and alternative sources of income. The recent focus on ecotourism (i.e., boardwalk construction inside the mangroves near Banjul city) received a positive response from the local stakeholders (i.e., users, government, and non-government organizations), with their appropriate roles in sharing the revenue, rights, and responsibilities of this project. Though the guidelines for conservation and management of the TWNP seem to be compatible, the harmony between local people and sustainable resource utilization should be ascertained. copyright; Royal Swedish Academy of Sciences 2012.

De Geus B.,Vrije Universiteit Brussel | Degraeuwe B.,Flemish Institute for Technological Research | Vandenbulcke G.,Universitecatholique Of Leuven Ucl | Int Panis L.,Flemish Institute for Technological Research | And 5 more authors.
Journal of Physical Activity and Health | Year: 2014

Background: For an accurate estimation of health benefits and hazards of utilitarian cycling, a prospective collection of bicycle usage data (exposure) is fundamental. Individual and environmental correlates are necessary to guide health promotion and traffic safety issues. Firstly, this study aims to report on utilitarian bicycle usage in Belgium, using a prospective data collection in regular adult commuter cyclists. Secondly, the association is explored between the individual variation in bicycle usage and individual and environmental correlates. Methods: 1187 regular adult cyclists filled out travel diaries prospectively. Multivariate linear regression with Stepwise selection (SMLR) models studied the association between exposure and individual and environmental correlates. Results: Higher age and availability of cycle paths have a positive association with bicycle usage to work. Women cycle significant less compared with men, and so do cyclists with 'poor' or 'average' health. Living in an urban crown (opposed to city center) and living in Flanders (opposed to Brussels or Wallonia) is associated with significantly more cycling. Conclusions: Utilitarian cycling is related to regional differences, level of urbanization of the place of residence, availability of bicycle paths, and gender. These findings are useful in estimating health benefits and hazards of utilitarian cycling among regular Belgian cyclists. © 2014 Human Kinetics, Inc.

Cartiaux O.,Universitecatholique Of Leuven Ucl | Paul L.,Universitecatholique Of Leuven Ucl | Francq B.G.,Catholic University of Leuven | Banse X.,Universitecatholique Of Leuven Ucl | And 3 more authors.
Annals of Biomedical Engineering | Year: 2014

In orthopaedic surgery, resection of pelvic bone tumors can be inaccurate due to complex geometry, limited visibility and restricted working space of the pelvis. The present study investigated accuracy of patient-specific instrumentation (PSI) for bone-cutting during simulated tumor surgery within the pelvis. A synthetic pelvic bone model was imaged using a CT-scanner. The set of images was reconstructed in 3D and resection of a simulated periacetabular tumor was defined with four target planes (ischium, pubis, anterior ilium, and posterior ilium) with a 10-mm desired safe margin. Patient-specific instruments for bone-cutting were designed and manufactured using rapid-prototyping technology. Twenty-four surgeons (10 senior and 14 junior) were asked to perform tumor resection. After cutting, ISO1101 location and flatness parameters, achieved surgical margins and the time were measured. With PSI, the location accuracy of the cut planes with respect to the target planes averaged 1 and 1.2 mm in the anterior and posterior ilium, 2 mm in the pubis and 3.7 mm in the ischium (p<0.0001). Results in terms of the location of the cut planes and the achieved surgical margins did not reveal any significant difference between senior and junior surgeons (p = 0.2214 and 0.8449, respectively). The maximum differences between the achieved margins and the 10-mm desired safe margin were found in the pubis (3.1 and 5.1 mm for senior and junior surgeons respectively). Of the 24 simulated resection, there was no intralesional tumor cutting. This study demonstrates that using PSI technology during simulated bone cuts of the pelvis can provide good cutting accuracy. Compared to a previous report on computer assistance for pelvic bone cutting, PSI technology clearly demonstrates an equivalent value-added for bone cutting accuracy than navigation technology. When in vivo validated, PSI technology may improve pelvic bone tumor surgery by providing clinically acceptable margins. © 2013 Biomedical Engineering Society.

Porporato P.E.,Universitecatholique Of Leuven Ucl | Payen V.L.,Universitecatholique Of Leuven Ucl | Perez-Escuredo J.,Universitecatholique Of Leuven Ucl | De Saedeleer C.J.,Universitecatholique Of Leuven Ucl | And 10 more authors.
Cell Reports | Year: 2014

Metastatic progression of cancer is associated with poor outcome, and here we examine metabolic changes underlying this process. Although aerobic glycolysis is known to promote metastasis, we have now identified a different switch primarily affecting mitochondria. The switch involves overload of the electron transport chain (ETC) with preserved mitochondrial functions but increased mitochondrial superoxide production. It provides a metastatic advantage phenocopied by partial ETC inhibition, another situation associated with enhanced superoxide production. Both cases involved protein tyrosine kinases Src and Pyk2 as downstream effectors. Thus, two different events, ETC overload and partial ETC inhibition, promote superoxide-dependent tumor cell migration, invasion, clonogenicity, and metastasis. Consequently, specific scavenging of mitochondrial superoxide with mitoTEMPO blocked tumor cell migration and prevented spontaneous tumor metastasis in murine and human tumor models. © 2014 The Authors.

Deltour J.,Universitecatholique Of Leuven Ucl | D'herdt P.,Belgian Building Research Institute BBRI | Deneyer A.,Belgian Building Research Institute BBRI | Bodart M.,Universitecatholique Of Leuven Ucl
Light and Engineering | Year: 2011

The use of energy efficient lighting in dwellings in combination with the preservation, or the improvement of visual comfort is a huge challenge. This paper presents a lighting renovation project in eight social apartments, in Belgium. The lighting system was renovated at four levels of quality, in order to evaluate the light saving potential, the lighting comfort and the influence of the human behaviour on the lighting consumption. The methodology dealt with the criteria and targets of the lighting renovation, the way to record monitoring data and the concept of the extrapolation of consumption. This extrapolation presented a way to obtain more case studies without knowing the occupancy schedule of the occupants. Illuminance, power, luminance, UGR values reached for the different lighting solutions were determined. The measurements showed that if the occupant selected his lighting installation, the comfort is seldom reached. Replacing initial lamps (incandescent) by high efficient compact fl uorescent lamps induced high energy savings and comfort level was reached more often. The visual comfort (higher illuminance level) could even be improved by the use of efficient luminaires. Finally, the paper concludes that, the human behaviour has a large influence on the lighting installation and consumption. Moreover, occupants tended to install the worst lighting equipment (high power level, low visual comfort). However efficient luminaries are not widespread on the domestic lighting market. On the other hand, the extrapolation allowed concluding that for some behaviour profiles there were no economic gains from the use of economic lamps and efficientluminaires. With this study, we point to the importance of evaluating correctly the needs of the occupants in terms of visual comfort and to install adequate energy saving lamps and luminaires.

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