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Agadir, Morocco

Chafchaouni-Moussaoui I.,Universiapolis | Charrouf Z.,University Mohammeddal | Guillaume D.,French National Center for Scientific Research
Natural Product Communications | Year: 2013

During the last two decades, the argan tree has been the subject of intensive phytochemical investigation. If argan oil is the most known argan derivative, argan saponins are frequently considered as molecules presenting a strong economic potential. This review presents an update of the current research efforts on argan saponins from around the world. Research evidence suggests that arganine C can be considered as a lead compound for new antivirals. Source

Lima-Tenorio M.K.,University of Lyon | Lima-Tenorio M.K.,State University of Maringa | Lima-Tenorio M.K.,CNRS Automation and Process Engineering Laboratory | Pineda E.A.,State University of Maringa | And 6 more authors.
Colloids and Surfaces B: Biointerfaces | Year: 2016

Aminodextran (AMD) polymer was prepared via chemical grafting of hexamethylenediamine on oxidized dextran. Magnetic latex particles were successfully obtained by adsorption of positively charged AMD on negatively charged submicron magnetic emulsion. The adsorbed amount was found to be ranged from 20 to 1280 mg of AMD per gram of dried magnetic dispersion. The AMD-coated magnetic emulsions were characterized by positive zeta potential in the pH range from 3 to 9 compared to bare seed magnetic emulsion. All the samples showed to be superparamagnetic property, even after the adsorption of the polymer. The developed magnetic submicron particles exhibited good potential for in vivo biomedical diagnosis applications as demonstrated by their higher T2 contrast-ability compared to Gd in magnetic resonance imaging (MRI) and hyperthermia. © 2016 Elsevier B.V. Source

Lococo D.,University Claude Bernard Lyon 1 | Lococo D.,CNRS Automation and Process Engineering Laboratory | Mora-Huertas C.E.,University Claude Bernard Lyon 1 | Mora-Huertas C.E.,CNRS Automation and Process Engineering Laboratory | And 5 more authors.
Journal of Biomedical Nanotechnology | Year: 2012

This research work deals with the development of argan oil-based nanoemulsions as vehicle of hydrophobic drugs such as diclofenac used as model. Nanoemulsions of oil in water were prepared using the ultrasonication method in order to obtain submicron size colloidal dispersion. The size, zeta potential and encapsulation efficiency of the dispersions obtained were investigated. In addition, the ability of sorbitan ester derivatives to form nanovesicles (niosomes), which in turn were used for encapsulating drug in oily solutions forming stable nanoemulsions, was particularly examined. Thus, additional stabilizing agents were not required in the recipe and formulations using only sorbitan monolaurate, argan oil and water lead to attractive results. Their submicronic size (<250 nm), high negative zeta potential (between -40 and -50 mV) and drug-encapsulation efficiency (higher than 85%) allow predicting both a good physical stability and a good performance as drug carriers. Copyright © 2012 American Scientific Publishers All rights reserved. Source

Gourgue H.,Laboratoire Of Thermodynamique Et Energetique Lte | Gourgue H.,Laboratoire Of Materiaux Et Energies Renouvelables Lmer | Gourgue H.,Universiapolis | Aharoune A.,Laboratoire Of Thermodynamique Et Energetique Lte | Ihlal A.,Laboratoire Of Materiaux Et Energies Renouvelables Lmer
Journal of Materials and Environmental Science | Year: 2015

This work presents a study of the atmospheric dispersion of emissions, particularly those of NOx (NO + NO2), generated by one or more stacks (five in our case). A numerical simulation of the dispersion of pollutants emitted by sources was performed on an area up to 3 Km2 using an improved Gaussian model. A validation of this model was performed using a close comparison with measurements (previous works) .Finally, a study of various scenarios aimed to reducing the impact of these pollutants on the area was carried out by studying the influence of different parameters (the number of emission points, stack height, atmospheric stability, speed and wind direction,...) on the dispersion of pollutants. The obtained results are of great interest for the improvement of evacuation devices to significantly reduce emissions and improve the air quality in the surrounding industrial sites. Source

Massaq A.,Caddi Ayad University | Rusinek A.,University of Lorraine | Klosak M.,Universiapolis | Klosak M.,Wroclaw University | And 2 more authors.
Tribology International | Year: 2016

The Hopkinson Split Pressure Bar system allows to carry out compression tests at high impact velocities corresponding to high strain rates up to 5000 s-1. For composite materials, however, negative phenomena related to wave propagation and specimen geometry may disturb experimental analysis and, therefore, should be taken into account. Potential errors are mainly due to friction, inertia and wave dispersion. In order to provide a complete analysis of experimental results for composite materials under dynamic compression, a procedure was developed to estimate friction and dispersion effects at the specimen-bar contact zone. For this purpose, dynamic tests were carried out on woven glass-fiber-reinforced Polyamide (PA6) composites using Hopkinsons bar and pin-on-disk tribometer tests techniques. Results showed that the state of friction characterizing the PA6/glass material differs as per the orientation of fibers. The frictional regime is relatively more severe in case where the fibers are normal to the direction of friction. © 2016 Elsevier Ltd. Source

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