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Bravo-Valenzuela N.J.M.,University of Taubaté | Passarelli M.L.B.,Santa Casa de Sao Paulo | Nascimento L.F.C.,UNITAU
Brazilian Journal of Cardiovascular Surgery | Year: 2011

Objective: To evaluate the impact of congenital heart diseases in growth of children with Down syndrome (DS) and the weight-height recovery after surgical correction. Methods: Retrospective study of the DS patients between 1984 and 2007. Excluding the mosaics and/or patients with associated morbidities (n=165). Calculated Z scores for weight (Zwb) and length (Zlb) at birth. Those submitted to surgical correction (n= 60) these scores (Zw/Zh) were evaluated before surgery and in subsequent periods to five years. Malnutrition was defined as weight/height Z-score ≤ 2,5. Used chi-square test to verify the relation between weight/length and age at the time of surgery and Student T test to evaluate the postoperative (PO) time of recovery (P ≤ 0.05). Results: Means Zwb (n = 162) and Zlb (n = 156) were -0.95 (±1.27) and -1.348 (±1.02). From the total data (n = 165), 65.5% (n = 108) presented heart disease. Those submitted to cardiac surgery (n = 60), Zw was below -2.5 in 55% (n = 33) and Zh in 60% (n = 36). After six months PO, 67.4% achieved Zw ≥ 2.5. In one year, 85.7% achieved Zh ≥ 2.5. Dividing this group by age in tertiles at time of surgery no difference was found. Conclusions: We concluded that malnutrition common in children with DS since birth. DS children with congenital heart and surgical indication were smaller and lighter than those without or with mild disease. PO recovery occurred in 6 months for weight and one year for height, with no difference in the age at the time of surgery.

Varallo A.C.T.,UNITAU | Souza C.F.,Anhanguera
Revista Brasileira de Engenharia Agricola e Ambiental | Year: 2010

The reuse of treated sewage effluent to water bodies to supply water for irrigation has been of great advantage to agriculture, and the use if not regimented could bring changes in physical and chemical properties of soil. This paper aimed the evaluation of the physical and chemical properties alteration of a Red-yellow Latosol after the application of reuse water from an effluent treatment station of wetlands. The experiment was accomplished in laboratory using a soil column. First, 15 L of distilled water were applied in the soil column and after 15 L of reuse water and at interval of 5 L of water a sample was collected for analysis. The results showed decrease of nitrate, potassium and saturated hydraulic conductivity values and an increase in sodium, iron, manganese, zinc and electrical conductivity of the soil after water application. In this way, it may be concluded that the use of waste water for agronomic activities must be used in a rational way, mainly checking the elevation of sodium.

Campos J.R.C.,Paulista University | Martins I.A.,UNITAU | Haddad C.F.B.,Claro | Kasahara S.,Paulista University
Folia Biologica (Czech Republic) | Year: 2012

The genus Holoaden includes three species described so far, but the only published cytogenetic data is from Holoaden bradei, with the karyotype 2n = 18, based on conventional staining. In the present paper we report, for the first time, data on chromosomes of H. luederwaldti, which presented 2n = 18 and a case of natural triploidy, with 2n = 3x = 27. In this sample, another karyotypic variation was observed due to the occurrence of two types of chromosome 8, which present submetacentric or subtelocentric morphologies. Homomorphic subtelocentric or heteromorphic condition was observed among the diploid specimens, whereas the triploid had one submetacentric and two subtelocentric chromosomes 8. In all specimens, Ag-NOR was located in the long arms of chromosomes 8, at the interstitial region when subtelocentric, or in the proximal region when submetacentric, confirmed by fluorescent in situ hybridization with the HM123 probe. The C bands showed centromeric distribution and distribution at Ag-NOR site. The centromeric heterochromatin was fluorescent with DAPI staining, whereas the Ag-NOR displayed bright fluorescence with CMA3. Fluorescent in situ hybridization using a telomeric probe labelled exclusively the telomere regions. Although the same 2n = 18 chromosome numbers have been observed in H. luederwaldti and H. bradei, some differences in both karyotypes can be visualized, mainly with regard to the morphology of the last chromosome pairs.

Amancio C.T.,University of Taubaté | Nascimento L.F.C.,Unitau
Revista da Associacao Medica Brasileira | Year: 2012

Objective: To estimate the risk of hospitalization for asthma in children after exposure to air pollutants in a medium-sized city in Southeast Brazil. Methods: An ecological time series study was carried out with hospitalization data for asthma in children under 10 years of age living in São José dos Campos, SP, Brazil, and concentrations of particulate matter with aerodynamic diameter < 10 microns, sulfur dioxide, and ozone; data were also obtained on relative humidity and temperatures. Pearson's coefficient correlation was used for the study variables. To estimate the association between hospitalizations due to asthma and air pollutants, Poisson regression generalized additive models were built, according to lags of up to seven days. Results: There was a strong correlation between hospitalizations and the pollutants particulate matter and sulfur dioxide. Exposure to particulate matter and sulfur dioxide were associated with significant relative risks of 1.01 to 1.04 of hospitalization due to asthma on the same day and within three days after exposure. Increases in the concentrations of these pollutants increase the risk of hospitalization between 8% and 19%. Conclusion: There is evidence of the effect of air pollutants on asthma hospitalization in a medium-sized city in Southeast Brazil. © 2012 Elsevier Editora Ltda. All right reserved.

Nascimento L.F.C.,Unitau | Costa T.M.,Unitau | Zollner M.S.A.C.,Unitau
Revista Paulista de Pediatria | Year: 2013

Objective: To identify the spatial pattern of low birth weight infants in the city of Taubaté, São Paulo, Southeast Brazil. Methods: Ecological and exploratory study, developed with the data acquired from the Health Department of Taubaté, regarding the period from January 1st 2006 and December 31st 2010. Birth certificates were used to obtain the data from infants weighing less than 2500g. A digital basis of census tracts was applied and the Global Moran index (IM) was estimated. Thematic maps were built for the distribution of low birth weight, health centers and tracts, according to the priority care (Moran map). The adopted statistical significance was α=5% and TerraView software conducted the spatial analysis. Results: There were 18,915 live births during the study period, with 1,817 low birth weight infants (9.6%). The low birth weight infants' prevalence during the period ranged from 9.3 to 9.8%. A total of 1,185 infants with known addresses, compatible with the digital base (65.2% of low birth weight infants), were included. The IM for low birth weight was 0.12, with p<0.01; regarding the health centers distribution, IM was -0.07, with p=0.01. The Moran map identified 11 census tracts with high priority for intervention by health managers, located in the outskirts of the city. Conclusions: The spatial analysis identified the low birth weight distribution by census tracts and the sectors with a high priority for intervention.

Ferri-de-Barros J.E.,University of Taubaté | de Alencar M.J.,UNITAU | Berchielli L.F.,University of Campinas | Castelhano Junior L.C.,UNITAU
Arquivos de Neuro-Psiquiatria | Year: 2011

Headaches occur frequently and thus are a key component of sociocentric medical education. Objective: To study headaches among students of medicine and psychology in a single university. Method: This was a questionnaire-based survey of a cohort of students of medicine and psychology. Results: The overall lifetime prevalence of headache was 98% and over the last year, 91%. Tensional headache accounted for 59% and migraine 22% in medicine; and 48.5% and 32% respectively in psychology. Forty-five percent reported that headaches had a variable sporadic impact on their productivity. The self-medication rate was 77%. Thirty-six percent reported worsening since admission to the university. Conclusion: The prevalence of headaches was very high. Tension-type headaches predominated in males and migraine in females. Tension-type was more frequent among medical students than among psychology students; migraine was more frequent in psychology (more females) than in medicine. Both kinds of students reported that headaches caused low interference with daily activities. The students reported that their symptoms had worsened since admission to the university.

Pugacheva G.,Russian Academy of Sciences | Martin I.,UNITAU | Spjeldvik W.,Weber State University
Journal of Physics: Conference Series | Year: 2013

We have demonstrated a reasonably satisfactory agreement between the theoretically simulated geomagnetically confined antiproton fluxes and the Pamela experimentally observed antiproton fluxes within the Earth's magnetosphere. The antiprotons were considered created partially in nuclear reactions of direct proton/antiproton production (p+p, p+pbar+p+p) and to an even larger extent in nuclear reactions of neutron/antineutron (indirect) pair production (p+p, n+nbar+p+p) both processes resulting from cosmic rays interactions with the Earth's upper atmosphere. Although the theoretically predicted spectrum of trapped antiprotons is not a perfect match in all details with the in-situ observed flux spectra, we do note an excellent antiproton flux match around 1 GeV kinetic energy. Thus, we conclude that what we earlier had largely predicted, the Pamela antiproton detection experiment has now observed.

Gusev A.A.,Russian Academy of Sciences | Martin I.M.,UNITAU
Journal of Atmospheric and Solar-Terrestrial Physics | Year: 2012

An assumption of the existence of natural climatic oscillations driven by solar activity enables an explanation of phase differences between variations in solar activity and rainfall level in Fortaleza, Brazil. Decadal and interdecadal variations in rainfall level can be reproduced using a forced oscillation equation with a driving force term that describes the variation in the sunspot number and with the assumption of the existence of 31.7-year interdecadal and 12.96-year decadal natural climatic oscillations. This equation satisfactorily reproduces the periodicity with a length of approximately 22. yr in the interdecadal rainfall variation before and up to the middle of the past century as well as the subsequent phase inversion, period and amplitude increase in the variation that followed the corresponding increases in the interdecadal sunspot number variation. The equation accurately reproduces the irregular phase shifts between decadal variations in rainfall level and in sunspot number over the entire 160. yr of recorded observations. © 2012 Elsevier Ltd.

Objective: To analyze the relationship between exposure to air pollutants and hospitalizations due to pneumonia in children of Sorocaba, São Paulo, Brazil. Methods: Time series ecological study, from 2007 to 2008. Daily data were obtained from the State Environmental Agency for Pollution Control for particulate matter, nitric oxide, nitrogen dioxide, ozone, besides air temperature and relative humidity. The data concerning pneumonia admissions were collected in the public health system of Sorocaba. Correlations between the variables of interest using Pearson cofficient were calculated. Models with lags from zero to five days after exposure to pollutants were performed to analyze the association between the exposure to environmental pollutants and hospital admissions. The analysis used the generalized linear model of Poisson regression, being significant p<0.05. Results: There were 1,825 admissions for pneumonia, with a daily mean of 2.5±2.1. There was a strong correlation between pollutants and hospital admissions, except for ozone. Regarding the Poisson regression analysis with the multi-pollutant model, only nitrogen dioxide was statistically significant in the same day (relative risk - RR=1.016), as well as particulate matter with a lag of four days (RR=1.009) after exposure to pollutants. Conclusions: There was an acute effect of exposure to nitrogen dioxide and a later effect of exposure to particulate matter on children hospitalizations for pneumonia in Sorocaba.

PubMed | University of Taubaté and Unitau
Type: Journal Article | Journal: Revista da Associacao Medica Brasileira (1992) | Year: 2016

The aim of this study was to estimate the association between expo sure to air pollutants and hospitalization for pneumonia among children in a medium-sized city located in the sugar cane plantation region of So Paulo State.An ecological time-series study was conducted with daily data of hospi talization for pneumonia including children aged 10 years or younger living in Ar araquara, state of So Paulo, from January 1st, 2010, to November 30th, 2012. To es timate the association between hospitalization due to pneumonia and particulate pollutants with aerodynamic diameter less than 10 m, nitrogen dioxide and ozone, relative risks for hospitalization according to a generalized additive model of Pois son regression, with Lags of up to five days, were calculated. A percentage increase (PI) was obtained for relative risk (IRR - increase on relative risk) of hospitalization at each 10 g/m3 increment in each air pollutants adjusted for the remaining.A total of 234 hospitalizations were recorded during these three years. There was a strong association between hospitalization and PM10 and NO2. The PI in relative risk was 15% to PM10 in Lag 0 and 7% points in Lag 1 for NO2.There was evidence of the action of air pollutants on hospitaliza tion for pneumonia in a medium-sized city located in a region affected by air pollution from sugarcane burning and the data presented here provide subsi dies for the implementation of public policies aiming to decrease this risk.

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