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Sammichele di Bari, Italy

Pepe M.,Unita Operativa Cardiologia Universitaria | Furgieri A.,GVM Care and Research | Miranda M.,GVM Care and Research | Cafaro A.,Unita Operativa Cardiologia Universitaria | And 4 more authors.
Future Cardiology | Year: 2015

Acute lower extremities peripheral artery disease represents a clinical emergency. Peripheral artery disease incidence ranges from 2.5 to 22% and has progressively increased due to the world population aging phenomenon and associates with coronary artery disease with a rate of 40-60%. The authors present the case of an 89-year-old man coming to their attention with acute lower extremities ischemia and unstable angina. Despite the short-to-midterm favorable outcome, doubts remain about the opportunity of treating 'very old' patients. The lack of dedicated randomized trials and of defined guidelines is a problem the scientific community needs to face considering that patients over 85 years represent a raising quote of the whole population of our catheterization laboratories. © 2015 Future Medicine Ltd.

Pepe M.,Unita Operativa Cardiologia Universitaria | Paradies V.,Unita Operativa Cardiologia Universitaria | Bortone A.,Unita Operativa Cardiochirurgia Universitaria | De Cillis E.,Unita Operativa Cardiochirurgia Universitaria | And 5 more authors.
Future Cardiology | Year: 2016

Takotsubo cardiomyopathy (TTC) is a form of acute left ventricular dysfunction usually reversible and with favorable prognosis. Ventricular septal perforation (VSP) is a very rare life-threatening complication. Percutaneous closure of VSP, despite being challenging, is a possible alternative to surgical repair. We present the first case of an 84-year-old patient with a TTC-related VSP treated by percutaneous approach. The case highlights the need of reconsidering the worldwide accepted consideration of TTC as benignant and allows some speculations on the optimal management of VSP in terms of timing, patient selection and possible alternative interventions. © 2016 Future Medicine Ltd.

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