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PubMed | Carol Davila University of Medicine and Pharmacy, UNIPAR, Queen's University of Belfast, University of Tartu and 41 more.
Type: Journal Article | Journal: Clinical kidney journal | Year: 2016

This study provides a summary of the 2010 European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry Annual Report (available at www.era-edta-reg.org).This report includes data on renal replacement therapy (RRT) using data from the national and regional renal registries in 29 countries in Europe and bordering the Mediterranean Sea. Individual patient data were received from 27 registries, whereas 18 registries contributed data in aggregated form. We present incidence and prevalence of RRT, transplant rates, survival probabilities and expected remaining lifetimes. The latter two are solely based on individual patient records.In 2010, the overall incidence rate of RRT for end-stage renal disease (ESRD) among all registries reporting to the ERA-EDTA Registry was 123 per million population (pmp) (

Rodrigues R.,UNIPAR | Feitosa K.P.S.,State University of Maringá | Felisberto Jr. A.M.,UNINGA | Barrena H.C.,State University of Maringá | And 2 more authors.
Pharmacological Reports | Year: 2011

The liver glucose production (LGP) levels of 15-h overnight fasted weaned rats submitted to short-term insulin-induced hypoglycemia (ST-IIH) and long-term IIH (LT-IIH) were compared. Experiments to characterize ST-IIH or LT-IIH that followed an intraperitoneal (ip) injection (1.0 U/kg) of regular (ST-IIH) or insulin detemir (LT-IIH) were performed and glycemia were measured 0 (normoglycemic control), 0.5 h (ST-IIH), 4 h and 6 h (LT-IIH) later. The values of glycemia (mg/dl) were 77.8 ± 7.2 (normoglycemic control), 26.2 ± 6.1 (ST IIH 0.5 h), 21.2 ± 7.6 (LT-IIH 4 h) and 35.3 ± 14.5 (LT-IIH 6.0). The LGP levels were measured in the rats submitted to ST-IIH (0.5 h) and LT-IIH (4 h or 6 h). The rats that received ip saline were used as the normoglycemic control group (COG). The livers from the COG and IIH groups (ST-IIH or LT-IIH) were perfused in situ with infusion of L-alanine (5 mM), L-glutamine (10 mM), glutamine dipeptide (5 mM), L-lactate (2 mM) or glycerol (2 mM). The ST-IIH rats showed a higher LGP level than COG group following the L-glutamine infusion (p < 0.05), but the LGP levels that were measured following the L-lactate, L-alanine, glutamine dipeptide (5 mM), L-lactate (2 mM) or glycerol infusion remained unchanged. Moreover, if the period of IIH was expanded to 4 h following insulin injection, the LGP levels induced by L-alanine, glutamine dipeptide or glycerol infusion also increased (p < 0.05, LT-IIH vs. COG). However, the LGP from the L-lactate infusion remained unchanged until 6 h after insulin injection. In conclusion, these results suggest that the intensification of liver gluconeogenesis during ST-IIH and LT-IIH in weaned rats is not a synchronous "all or nothing" process; instead, this process integrated in a temporal manner and is specific for each gluconeogenic substrate. Copyright © 2011 by Institute of Pharmacology Polish Academy of Sciences.

News Article | February 10, 2017
Site: www.rechargenews.com

With domestic orders dwindling fast, Brazilian glass-fibre and epoxy blade-maker Tecsis is taking steps to increase exports to around 70% of its output, up from around 45% over the past two years – a push that will go hand in hand with efforts to diversify its client base to mitigate any fallout from GE’s acquisition of LM Windpower. “Increasing our client base has been our main task since last year,” CEO Fabiano Mori tells Recharge, pointing out that GE has cancelled orders through 2019 that had been placed by Alstom for local onshore projects, before the US group’s 2015 acquisition of the French OEM. Tecsis is the oldest and largest blade maker in Brazil, founded in 1995. With 50,000 units manufactured since its creation, Tecsis now has capacity to make blades longer than 60 metres in Brazil, competing on a global scale, and with local rival Aeris and the Brazilian unit of LM Windpower. According to a 2015 study by the Brazilian Industrial Development Agency (ABDI), Tecsis had a capacity to produce more than 6,000 blades annually in São Paulo, which compares with a capacity of 1,000 at LM Windpower, Aeris’s 600 blade capacity, and Enercon’s 1,500 blade-a-year vertical production arrangement. With a production hub in the state of São Paulo and a newly-opened factory in the northeastern state of Bahia – to supply GE and former Alstom projects in the country’s Northeastern region – Tecsis has been adapting to the new conditions in the Brazilian and global markets. Since late-2011, the company has been controlled and managed by Brazilian investment advisory company Estáter, while Brazilian petrochemical group Unipar and the investment arm of the Brazil’s Development Bank (BNDES) are also shareholders. During this period, Tecsis has undergone several bouts of production restructuring, the latest of which aimed to adapt the company to the current situation of Brazil’s troubled wind power market. With wind tenders in Brazil currently suspended because of declining power demand, the local wind sector is looking at a cliff-edge of orders starting from 2019, when some 8GW of contracted capacity will be completed. According to projections by the Brazilian Wind Power Association (ABEEólica), in 2017 and 2018 some 2.3GW of new wind will be installed, but in 2019 demand will drop to some 1.2GW, declining further to 500MW and 600MW in 2020 and 2021. After that, no significant orders are seen due to the lack of tenders. “The cancellation of the tender was horrible. There will be a gap of one or two years in the market ... so we are already seeing idle capacity in our factories, and although our adjustment was mostly concluded in 2016, we will see more than 50% decline in output in 2017 from 2016,” says Mori. With 40% idle capacity in its production hub in São Paulo, and a slow ramp-up in Bahia, which today is still 50% idle, the company has shed workers in São Paulo – some 1,500 out of a previous workforce of over 5,000 – and further streamlined its built-to-spec production processes. “This is how we gain competitiveness: innovating in production processes and researching materials, but we have the price and the quality to compete abroad and in Brazil,” says Mori. Like all OEMs in Brazil, blade makers also face the crucial challenge of keeping the supply chain alive for when Brazil’s wind market revives after 2020. “The supply chain, especially the units of foreign companies here in Brazil, will have to export to fill the order gap, but some may close up shop. So a tender in 2017 is needed to give a positive signal to the supply chain,” he says. Just as important as keeping suppliers ticking over is the diversification of Tecsis’s client base. Although Tecsis now supplies to most global OEMs abroad and in Brazil – including Acciona, and Gamesa – about 80% of its production is taken up by GE, which in Brazil alone has a 30% market share following the acquisition of Alstom's onshore manufacturing facilities there. It is not yet known whether the new GE-controlled LM Windpower will continue to supply blades to competing OEMs. But Mori believes that the outsourcing trend for blades will continue, and some of LM’s current clients will be looking for alternative suppliers in the near future. In Brazil, for example, Gamesa is questioning GE’s planned acquisition of LM at the antitrust board CADE. The Spanish company claims it will be hurt if GE has information about turbine prices, projects and designs currently accessible to LM Windpower, which manufactures blades for its G114 and G97 machines currently assembled in Brazil. While the fight for the Brazilian blade market goes on in the antitrust court, Tecsis’s biggest export destination will continue to be the US market. Mori claims demand for blades cannot be supplied solely by local companies, and especially by US market leader TPI Composites. Europe is Tecsis's second biggest export market, Mori adds. But with Latin American markets such as Mexico and Argentina opening up and a growing market in Africa, Mori believes Tecsis is well positioned to diversify its client base. “We are passing through a tough year but I am pretty confident that export market will lead the company to a turnaround. Where we export to depends on the strategy of the global OEMs,” he says. Mori pointed out that he has already closed a supply deal with Acciona in Argentina, but he sees Mexico as having the biggest export potential in Latin America.

Goncalves Jr. A.C.,West Parana State University | Meneghel A.P.,West Parana State University | Rubio F.,West Parana State University | Strey L.,West Parana State University | And 2 more authors.
Revista Brasileira de Engenharia Agricola e Ambiental | Year: 2012

This study evaluated the efficacy of moringa seeds (Moringa oleifera Lam.) as an adsorbent material for removing toxic heavy metals such as cadmium, lead, and chromium from contaminated solutions. The effect of the adsorbent mass was investigated at two pH conditions (5.0 and 7.0). The optimized conditions were 0.300 g of adsorbent at pH 5.0, used for the isotherms construction, and linearized according to Langmuir and Freundlich models. Results showed that cadmium adsorption was similar in both the models used. For lead, the Freundlich model had the best adjustment and chromium was better adjusted by the Langmuir model. It was concluded that the adsorbent was effective in the remediation of solutions containing cadmium, lead and chromium, thus, its use as sustainable alternative material is feasible, since it has low cost, does not need a previous treatment and it is a byproduct.

Goncalves Jr. A.C.,West Parana State University | Rubio F.,West Parana State University | Meneghel A.P.,West Parana State University | Coelho G.F.,West Parana State University | And 2 more authors.
Revista Brasileira de Engenharia Agricola e Ambiental | Year: 2013

This study aimed to evaluate the efficacy of crambe seeds (Crambe abyssinica Hochst) as adsorbent material in the removal of the toxic metals cadmium, lead and chromium from contaminated solutions. The byproduct was obtained from oil extraction of crambe seeds in a Soxhlet system. In kinetic tests, the adsorbent masses had varied in solutions containing the metals under pH 5.0 and 7.0. Metal concentrations were determined by flame atomic absorption spectrometry (FAAS). According to optimal conditions found, the adsorption assays were performed for obtaining the isotherms of each metal, which were linearized in agreement with the mathematical models of Langmuir and Freundlich. According to the obtained results, the adsorbent was effective in removing the assessed metals in aqueous solutions, being feasible its employment as an alternative material for the adsorption of metals, besides being a byproduct, which has undergone no prior treatment.

Hungria M.,Embrapa Soja | Kaschuk G.,UNIPAR
Environmental and Experimental Botany | Year: 2014

Legumes need large amounts of N to grow satisfactorily. Under low NO3 - availability in the soil, many legumes meet their N requirements by N2 fixation in association with rhizobia. Both NO3 - uptake and N2 fixation decrease as temperature exceeds optimal growth conditions, but the mechanisms of regulation of N2 fixation and NO3 -/NH4 + assimilation under high temperature stress are not completely understood. We describe an experiment in which physiological mechanisms regulating N metabolism of common bean (Phaseolus vulgaris L.) are investigated in plants submitted to daily maximum temperatures of 28, 34 and 39°C. Common bean was grown in symbiosis with each of six rhizobial strains-belonging to four different species and varying in N2 fixation effectiveness-or fertilized with NO3 - until flowering. Harvest measurements included the activities of shoot, stem and root NO3 - reductase (NR), nodule glutamine synthetase (GS), NADH-dependent glutamate synthase (GOGAT), nitrogenase, phosphoenol pyruvate carboxylase (PEPcase), N-export rates by nodules and concentration of N compounds in the xylem sap. Higher temperatures inhibited N2 fixation resulting in lower proportion of ureide-N in nodules and xylem sap of nodulated plants in relation to amide-N and α-amino-N. Higher temperatures consistently reduced the activity of NR in leaves of N-fertilized plants. Higher temperatures also decreased N exported from nodules and activities of nitrogenase, GS, GOGAT and PEPcase. The rate of decreases varied in plants with different strains. Furthermore, the activities of GS and GOGAT were more strongly affected by high temperatures than the activity of nitrogenase. There was a remarkable increase in the concentration of NH4 +-N and ureide-N in the nodules when GS and GOGAT activities decreased. Therefore, the results provide evidence that N2 fixation in common bean submitted to heat stress is limited by NH4 + assimilation via GS-GOGAT rather than by decreased activity of nitrogenase. Rhizobial effectiveness determined the degree of down-regulation of GS-GOGAT activity in nodule tissues. © 2013 Elsevier B.V.

Crop productivity and sustainability have often been related to soil organic matter and soil microbial biomass, especially because of their role in soil nutrient cycling. This study aimed at measuring fungal and bacterial biomass by epifluorescence microscopy and arbuscular mycorrhizal fungal (AMF) spore density in sugarcane (Saccharum officinarum L.) fields under different managements. We collected soil samples of sugarcane fields managed with or without burning, with or without mechanized harvest, with or without application of vinasse and from nearby riparian native forest. The soil samples were collected at 10cm depth and storage at 4°C until analysis. Fungal biomass varied from 25 to 37μg C g-1 dry soil and bacterial from 178 to 263μg C g-1 dry soil. The average fungal/bacterial ratio of fields was 0.14. The AMF spore density varied from 9 to 13 spores g-1 dry soil. The different sugarcane managements did not affect AMF spore density. In general, there were no significant changes of microbial biomass with crop management and riparian forest. However, the sum of fungal and bacterial biomass measured by epifluorescence microscopy (i.e. 208-301μg C g-1 dry soil) was very close to values of total soil microbial biomass observed in other studies with traditional techniques (e.g. fumigationextraction). Therefore, determination of fungal/bacterial ratios by epifluorescence microscopy, associated with other parameters, appears to be a promising methodology to understand microbial functionality and nutrient cycling under different soil and crop managements.

PubMed | Paranaense University and Unipar
Type: Journal Article | Journal: Revista da Associacao Medica Brasileira (1992) | Year: 2015

the Warwick-Edinburgh mental well-being scale (WEMWBS) was designed to assess the level of mental well-being of a population or specific groups. The scale consists of 14 items covering functional psychological aspects, as well as well-being. The final score is calculated by adding up the response of each item, ranging from 1 to 5, obtaining a result from 14 to 70 points.the procedure was developed in accordance with the protocol recommended by the World Health Organization covering translation, back translation, semantic equivalence, expert evaluation of the previous steps, pre-test and final version of the instrument. Following, the final version was applied to a sample of 122 individuals and the data were subjected to descriptive statistical analysis, factor analysis, internal consistency and correlation with other validated instruments.we performed the instruments adaptation to the Portuguese spoken in Brazil, replacing terms to approximate the language to expressions of everyday life. The final version showed similar results to those from the original version, demonstrated by factor analysis, internal consistency (Cronbachs alpha: 0.89) and positive correlation with instruments validated to the Portuguese language.the Brazilian version of the WEMWBS proved to be easy to use and understand, showed high internal consistency and construct validity similar to the original instrument.

News Article | December 27, 2016
Site: globenewswire.com

Brussels, December 27, 2016 --- Solvay has completed the sale of its 70.59% stake in Solvay Indupa to Brazilian chemical group Unipar Carbocloro, following the approval earlier this month of the Brazilian antitrust authority CADE. "The sale of Solvay Indupa, producers of PVC and caustic soda in Brazil and Argentina, marks another important step in Solvay's transformation," said Vincent De Cuyper, member of Solvay's Executive Committee.

D'Agostini E.C.,Unipar Laboratory Of Biologia Molecular | Mantovani T.R.D.,UNIPAR | do Valle J.S.,Unipar Laboratory Of Biologia Molecular | Colauto N.B.,UNIPAR | Linde G.A.,UNIPAR
Scientia Agricola | Year: 2011

Basidiomycetes are laccase producers used for hydrolysis of lignocellulosic byproducts in fermentative processes and could be used on biofuel production or ruminant feeding. The objective of this study was to evaluate the effect of concentrations of non-protein nitrogen sources on laccase production and mycelial growth of Pleurotus ostreatus, Lentinula edodes and Agaricus blazei. The fungi were grown on soybean hulls to which urea (U), ammonium sulfate (AS) or mixture of AS:U (1:1) were added to achieve carbon/nitrogen (C/N) ratios of 5, 15, 20 or 30. The average longitudinal mycelial growth was measured and laccase activity was determined by the oxidation of 2,2'-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid. Higher C/N ratios increased mycelial growth and decreased laccase production. The highest activities were obtained with a C/N ratio of 5. P. ostreatus, L. edodes and A. blazei produced more laccase when AS, AS:U and U, respectively, were added. In addition, C/N ratios lower than 30 induced laccase syntheses, inhibited mycelial growth and were a better condition for prehydrolysis of plant residues.

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