Goiânia, Brazil
Goiânia, Brazil

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Babeto E.,São Paulo State University | Rahal P.,São Paulo State University | Provazzi P.J.S.,São Paulo State University | Hidalgo C.A.,UNIP | Anselmo-Lima W.T.,University of Sao Paulo
Brazilian Journal of Otorhinolaryngology | Year: 2010

Rhinosinusal polyps physiopathology is not fully understand, despite numerous hypotheses regarding its inflammatory process. Aims: a prospective study regarding the gene expression of proteins: anexin-1 and galectin-1, which has an anti-inflammatory action and is modulated by steroids. Materials and Methods: eleven patients with rhinosinusal polyps suffered a biopsy of their polyps at two moments: in the absence of systemic steroids and during its use. In the two samples we assessed the expression of these genes and compared it to the normal nasal mucosa in the middle meatus. Results: We noticed that the mean expression of the genes which code anexin-1 and galectin-1 was predominantly increased, regardless of the use of steroids in relation to the control nasal mucosa. Notwithstanding, in polyps without the use of steroids, the mean gene expression of anexin-1 was significantly higher than in the polyps which were under the use of steroids. Regarding galectin-1, there was no significant difference between the expression mean values before and after the use of systemic steroids. Conclusion: The genes present an expression increase in the polyp mucosa, regardless of the use of steroids; nonetheless, the relationship of these two genes of anti-inflammatory proteins with steroids did not happen the same way.


Jeuffroy M.H.,French National Institute for Agricultural Research | Jeuffroy M.H.,Agro ParisTech | Baranger E.,French National Institute for Agricultural Research | Baranger E.,Agro ParisTech | And 9 more authors.
Biogeosciences | Year: 2013

Approximately 65 % of anthropogenic emissions of N2O, a potent greenhouse gas (GHG), originate from soils at a global scale, and particularly after N fertilisation of the main crops in Europe. Thanks to their capacity to fix atmospheric N2 through biological fixation, legumes can reduce N fertilizer use, and possibly N2O emissions. Nevertheless, the decomposition of crop organic matter during the crop cycle and residue decomposition, and possibly the N fixation process itself, could lead to N 2O emissions. The objective of this study was to quantify N 2O emissions from a dry pea crop (Pisum sativum, harvested at maturity) and from the subsequent crops in comparison with N2O emissions from wheat and oilseed rape crops, fertilized or not, in various rotations. A field experiment was conducted over 4 consecutive years to compare the emissions during the pea crop, in comparison with those during the wheat (fertilized or not) or oilseed rape crops, and after the pea crop, in comparison with other preceding crops. N2O fluxes were measured using static chambers. In spite of low N2O fluxes, mainly due to the site's soil characteristics, fluxes during the crop were significantly lower for pea and unfertilized wheat than for fertilized wheat and oilseed rape. The effect of the preceding crop was not significant, while soil mineral N at harvest was higher after the pea crop. These results should be confirmed over a wider range of soil types. Nevertheless, they demonstrate the absence of N2O emissions linked to the symbiotic N fixation process, and allow us to estimate the decrease in N2O emissions by 20-25 % through including one pea crop in a three-year rotation. On a larger scale, this reduction of GHG emissions at field level has to be added to the decrease due to the reduced production and transport of the N fertilizer not applied to the pea crop. © Author(s) 2013.


da Luz M.A.,Paulista University | Sousa M.V.,UNIP | Neves L.A.F.S.,UNIP | Cezar A.A.C.,UNIP | And 2 more authors.
Brazilian Journal of Physical Therapy | Year: 2015

Background: Kinesio Taping® has been widely used in clinical practice. However, it is unknown whether this type of tape is more effective than placebo taping in patients with chronic lower back pain. Objective: To compare the effectiveness of Kinesio Taping® in patients with chronic non-specific low back pain against a placebo tape and a control group. Method: This is a 3-arm, randomized controlled trial with a blinded assessor. Sixty patients with chronic non-specific low back pain were randomized into one of the three groups: Kinesio Taping® group (n=20), Micropore® (placebo) group (n=20) and control group (n=20). Patients allocated to both the Kinesio Taping® group and the placebo group used the different types of tape for a period of 48 hours. The control group did not receive any intervention. The outcomes measured were pain intensity (measured by an 11-point numerical rating scale) and disability (measured by the 24-item Roland Morris Disability Questionnaire). A blinded assessor measured the outcomes at baseline, 48 hours and 7 days after randomization. Results: After 48 hours, there was a statistically significant difference between the Kinesio Taping® group versus the control group (mean between-group difference = -3.1 points, 95% CI=-5.2 to -1.1, p=0.003), but no difference when compared to the placebo group (mean between-group difference= 1.9 points, 95% CI=-0.2 to 3.9, p=0.08). For the other outcomes no differences were observed. Conclusions: The Kinesio Taping® is not better than placebo (Micropore®) in patients with chronic low back pain. ClinicalTrials.gov number: NCT0200766. © 2015, Revista Brasileira de Fisioterapia. All rights reserved.


Sanchez J.H.,UNINOVE | Contador J.C.,UNIP | Contador J.L.,FACCAMP
Producao | Year: 2012

This article describes the methodology and the results of a qualitative empirical research carried out to identify the determinants of competitiveness of the most important compact automotive vehicles produced by the four major car manufacturers operating in Brazil: Fiat, Ford, General Motors and Volkswagen. The methodology chosen was the one recommended by the fields and weapons of the competition model, because it is both qualitative and quantitative, and also because it very clearly represents the competitive business and operational strategies of companies. The results confirmed the hypothesis that were validated by Popper's deductive method: 1) there is no statistically significant differences between the fields of competition chosen for the more competitive automotive vehicles and those chosen for the less competitive ones, once they all compete primarily on design, quality and price of product; 2) the focus (the mathematical variable that measures the alignment of the weapons of the competition with the fields of the competition selected for each vehicle) explains why a certain automotive vehicle is more competitive compared to the other.


Fortes R.C.,University of Brasilia | Fortes R.C.,Paulista University | Fortes R.C.,Hospital Regional da Asa Norte HRAN | Monteiro T.M.R.C.,UNIP | And 2 more authors.
Journal of Coloproctology | Year: 2012

Introduction: Colorectal cancer is one of the most prevalent neoplasms in the western world. Colostomy, temporary or permanent, can be a serious limiting factor affecting the quality of life of oncological patients. Objective: To compare the quality of life of oncological patients with definitive and temporary colostomy. Methods: Descriptive cross-sectional study carried out at a public hospital in Brasilia, Federal District of Brazil. The study analyzed 39 patients with colorectal cancer, 76.9% males, sorted into two groups: definitive ostomy (n=26) and temporary ostomy (n=13). The World Health Organization Quality of Life (WHOQOL)-bref questionnaire was used to assess the quality of life. Data were analyzed using Excel 2007 and Statistical Package for Social Sciences 19.0. Results: 50% of definitive and 76.9% of temporary ostomy patients reported that the physical pain did not interfere in the affairs. 38.5% of definitive and 46.2% of temporary ostomy accepted their physical appearance. 46.2% of definitive and 53.8% of temporary ostomy reported good quality of life. 84.6% of definitive and 46.2% of temporary ostomy did not enjoy their life. 50% of definitive and 53.8% of temporary ostomy were satisfied with their sleep. 57.7% of definitive and 53.8% of temporary ostomy considered the environments as healthy. Over 70% of definitive and over 50% of temporary ostomy had financial constraints and were dissatisfied with leisure opportunities, respectively. 69.2% of definitive and 46.2% of temporary ostomy presented lower libido. 88.5% of definitive and 61.5% of temporary ostomy attended the church. Conclusion: The results showed that temporary ostomy patients suffer the same afflictions as the patients with definitive ostomy, equally affecting the quality of life of these patients.


Schwann cells are recognized by their capacity of producing single internodes of myelin around axons of the peripheral nervous system. In the ethidium bromide (EB) model of primary demyelination in the brainstem, it is observed the entry of Schwann cells into the central nervous system in order to contribute to the myelin repair performed by the oligodendrocytes that survived to the EB gliotoxic action, being able to even remyelinate more than one axon at the same time, in a pattern of repair similar to the oligodendroglial one. The present study was developed in the spinal cord to observe if Schwann cells maintained this competence of attending simultaneously different internodes. It was noted that, on the contrary of the brainstem, Schwann cells were the most important myelinogenic cells in the demyelinated site and, although rare, also presented the capacity of producing more than one internode of myelin in distinct axons.


PubMed | Paulista University, City University of Sao Paulo and UNIP
Type: Journal Article | Journal: Brazilian journal of physical therapy | Year: 2015

Kinesio Taping has been widely used in clinical practice. However, it is unknown whether this type of tape is more effective than placebo taping in patients with chronic lower back pain.To compare the effectiveness of Kinesio Taping in patients with chronic non-specific low back pain against a placebo tape and a control group.This is a 3-arm, randomized controlled trial with a blinded assessor. Sixty patients with chronic non-specific low back pain were randomized into one of the three groups: Kinesio Taping group (n=20), Micropore (placebo) group (n=20) and control group (n=20). Patients allocated to both the Kinesio Taping group and the placebo group used the different types of tape for a period of 48 hours. The control group did not receive any intervention. The outcomes measured were pain intensity (measured by an 11-point numerical rating scale) and disability (measured by the 24-item Roland Morris Disability Questionnaire). A blinded assessor measured the outcomes at baseline, 48 hours and 7 days after randomization.After 48 hours, there was a statistically significant difference between the Kinesio Taping group versus the control group (mean between-group difference = -3.1 points, 95% CI=-5.2 to -1.1, p=0.003), but no difference when compared to the placebo group (mean between-group difference= 1.9 points, 95% CI=-0.2 to 3.9, p=0.08). For the other outcomes no differences were observed.The Kinesio Taping is not better than placebo (Micropore) in patients with chronic low back pain.


PubMed | Paulista University, City University of Sao Paulo and UNIP
Type: | Journal: Brazilian journal of physical therapy | Year: 2015

Kinesio Taping has been widely used in clinical practice. However, it is unknown whether this type of tape is more effective than placebo taping in patients with chronic lower back pain.To compare the effectiveness of Kinesio Taping in patients with chronic non-specific low back pain against a placebo tape and a control group.This is a 3-arm, randomized controlled trial with a blinded assessor. Sixty patients with chronic non-specific low back pain were randomized into one of the three groups: Kinesio Taping group (n=20), Micropore (placebo) group (n=20) and control group (n=20). Patients allocated to both the Kinesio Taping group and the placebo group used the different types of tape for a period of 48 hours. The control group did not receive any intervention. The outcomes measured were pain intensity (measured by an 11-point numerical rating scale) and disability (measured by the 24-item Roland Morris Disability Questionnaire). A blinded assessor measured the outcomes at baseline, 48 hours and 7 days after randomization.After 48 hours, there was a statistically significant difference between the Kinesio Taping group versus the control group (mean between-group difference = -3.1 points, 95% CI=-5.2 to -1.1, p=0.003), but no difference when compared to the placebo group (mean between-group difference= 1.9 points, 95% CI=-0.2 to 3.9, p=0.08). For the other outcomes no differences were observed.The Kinesio Taping is not better than placebo (Micropore) in patients with chronic low back pain.


The actions of the software products and processes improvement, for a better attendance of the business objectives of an organization, must be associated to the competitive market strategies. This paper describes a roadmap that translates the strategic objectives of the software organizations in managed process pointers. The Balanced Scorecard (BSC) and the Practical Software Measurement (PSM) are the basis of the proposed roadmap. This study is based on the concepts a bibliographical research and the research-action application. The research-action strategy gives refinement to the roadmap, enables the participants to learn and improves the method application. The execution of the methodological stages resulted in the definition of the strategic map and its development in the studied software organization. The final result is a roadmap that allows the implementation of an alignment between the business strategy and the processes improvement in software companies.


Gomes T.T.,São Paulo State University | Hassunuma R.M.,UNIP | Da Silva L.M.,UNIP
Revista Neurociencias | Year: 2014

Objective. To evaluate the gain of muscle strength and functional independence of a female patient with myelomeningocele and hydrocephalus, performing hippotherapy. Method. 31 weekly sessions of hippotherapy lasting 30 minutes each; at the first evaluation it was applied the Sensitivity Test; the Muscular Strength Test and the Functional Independence Measurement Form were applied at the beginning and after 3, 6 and 10 months of treatment. Results. The Sensitivity Test rated the lesion level at T10, classifying it as a complete lesion, with no motor or sensory function in sacral segments; the Muscle Strength Tests showed strength gains in some muscles, which enabled improvement in the functional independence of the patient. Conclusion. Based on the noted significant improvement in muscle and functional condition of the studied practitioner, it is suggested further research in order to contribute to establish the hippotherapy as a therapeutic method in myelomeningocele treatment. © 2015 Universidade Federal de Sao Paulo. All rights reserved.

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