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Raval A.P.,Un Mehta Institute Of Cardiology And Research Center Unmicrc | Shukla A.,Un Mehta Institute Of Cardiology And Research Center Unmicrc | Garg R.,Un Mehta Institute Of Cardiology And Research Center Unmicrc | Rana Y.,Un Mehta Institute Of Cardiology And Research Center Unmicrc | Shah K.,Un Mehta Institute Of Cardiology And Research Center Unmicrc
Revista Portuguesa de Cardiologia | Year: 2016

Multiple left ventricular aneurysms (LVAs) are rare, especially in a young female. A 29-year-old woman presented vague symptoms. Multiple LVAs were revealed and confirmed on different imaging modalities, including chest radiography, echocardiography, contrast ventriculography and cardiac magnetic resonance imaging. Detailed work-up for probable etiologies including ischemic, infectious, inflammatory and autoimmune causes was negative. In the absence of angina, decompensated congestive heart failure, arrhythmias and embolism, the patient was managed conservatively, with excellent mid-term outcome. © 2016 Sociedade Portuguesa de Cardiologia. Source


Shukla A.N.,Un Mehta Institute Of Cardiology And Research Center Unmicrc | Thakkar B.,Un Mehta Institute Of Cardiology And Research Center Unmicrc | Jayaram A.A.,Un Mehta Institute Of Cardiology And Research Center Unmicrc | Madan T.H.,Un Mehta Institute Of Cardiology And Research Center Unmicrc | Gandhi G.D.,Un Mehta Institute Of Cardiology And Research Center Unmicrc
Journal of Thrombosis and Thrombolysis | Year: 2014

Pulmonary embolism (PE) is a relatively common life-threatening cardiovascular condition associated with significant morbidity and mortality. We present the efficacy and safety data of weight-adjusted tenecteplase in 30 consecutive patients of acute PE. 30 patients (22 male, 8 female) with acute PE were included in the study and divided into three groups: (1) Acute PE complicated by shock stage and/or persistent hypotension (12 patients). (2) RV dilatation and/or dysfunction without hypotension (14 patients). (3) Severe hypoxemia without hypotension and RV dysfunction (4 patients). Predominant symptoms were dyspnoea, cough, chest pain, syncope and haemoptysis, noted in 100 % (30), 40 % (12), 54 % (16), 32 % (9) and 10 % (3) of patients respectively. RV dilatation and dyskinesia were present in 86 %, septal paradoxical movement in 73 % and inferior venacava collapse absent in 53 % of patients respectively. 12 patients presented with acute PE and cardiogenic shock, 14 patients showed RV dilatation and dysfunction with systolic BP >90 mmHg and four patients were having RV dilation without dysfunction but severe hypoxemia. There was significant reduction in right ventricular systolic pressure and improvement in right ventricular dysfunction. Our study shows that tenecteplase is very effective and safe in the treatment of PE with minimal risk of bleeding in high risk group and intermediate risk and even in selective low risk category group of patients. However, in view of small number of patients in study group, a large multicentre randomized study would be required to draw a firm conclusion regarding the thrombolysis in low risk category patient. © 2013 Springer Science+Business Media. Source

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