Ukrainian Academy of Sciences
Odessa, Ukraine

The National Academy of science of Ukraine is the highest research body in Ukraine, as a self-governing state-funded organization. It is the main research institution along with the five other academies specialized in various scientific disciplines. NAS Ukraine consists of numerous departments, sections, research institutes, scientific centers and various other supporting scientific organizations. The Academy reports on the annual basis to the Cabinet of Ministers of Ukraine.The presidium of the academy is located at the following address vulytsia Volodymyrska, 57, across the street from the Building of Pedagogical Museum where used to preside the Central Council during the independence period of 1917-18. Wikipedia.

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Ukrainian Academy of Sciences | Date: 2016-04-14

Application of the machine for flash-butt welding of rails with one rod, which connects two tong-type clamping devices is widening greatly the functional capabilities at its service, both in welding of separate rails and also in repair of rail tracks under the field conditions and in hard-to-reach places such as railway switches and frogs, the underground tracks, rails, which are laid side by side at a close distance, etc., not changing the optimum process and quality of the welded joints.

Agency: European Commission | Branch: H2020 | Program: ERA-NET-Cofund | Phase: SC5-15-2015 | Award Amount: 52.36M | Year: 2016

In the last decade a significant number of projects and programmes in different domains of environmental monitoring and Earth observation have generated a substantial amount of data and knowledge on different aspects related to environmental quality and sustainability. Big data generated by in-situ or satellite platforms are being collected and archived with a plethora of systems and instruments making difficult the sharing of data and knowledge to stakeholders and policy makers for supporting key economic and societal sectors. The overarching goal of ERA-PLANET is to strengthen the European Research Area in the domain of Earth Observation in coherence with the European participation to Group on Earth Observation (GEO) and the Copernicus. The expected impact is to strengthen the European leadership within the forthcoming GEO 2015-2025 Work Plan. ERA-PLANET will reinforce the interface with user communities, whose needs the Global Earth Observation System of Systems (GEOSS) intends to address. It will provide more accurate, comprehensive and authoritative information to policy and decision-makers in key societal benefit areas, such as Smart cities and Resilient societies; Resource efficiency and Environmental management; Global changes and Environmental treaties; Polar areas and Natural resources. ERA-PLANET will provide advanced decision support tools and technologies aimed to better monitor our global environment and share the information and knowledge in different domain of Earth Observation.

Mechanisms for maintenance of the extracellular level of glutamate in brain tissue and its regulation still remain almost unclear, and criticism of the current paradigm of glutamate transport and homeostasis has recently appeared. The main premise for this study is the existence of a definite and non-negligible concentration of ambient glutamate between the episodes of exocytotic release in our experiments with rat brain nerve terminals (synaptosomes), despite the existence of a very potent Na+-dependent glutamate uptake. Glutamate transporter reversal is considered as the main mechanisms of glutamate release under special conditions of energy deprivation, hypoxia, hypoglycemia, brain trauma, and stroke, underlying an increase in the ambient glutamate concentration and development of excitotoxicity. In the present study, a new vision on transporter-mediated release of glutamate as one of the main mechanisms involved in the maintenance of definite concentration of ambient glutamate under normal energetical status of nerve terminals is forwarded. It has been suggested that glutamate transporters act effectively in outward direction in a non-pathological manner, and this process is thermodynamically synchronized with uptake and provides effective outward glutamate current, thereby establishing and maintaining permanent and dynamic glutamatein/glutamateout gradient and turnover across the plasma membrane. In this context, non-transporter tonic glutamate release by diffusion, spontaneous exocytosis, cystine-glutamate exchanger, and leakage through anion channels can be considered as a permanently added 'new' exogenous substrate using two-substrate kinetic model calculations. Permanent glutamate turnover is of value for tonic activation of post/presynaptic glutamate receptors, long-term potentiation, memory formation, etc. Counterarguments against this mechanism are also considered. © 2016 by De Gruyter.

Agency: European Commission | Branch: H2020 | Program: CSA | Phase: INT-02-2015 | Award Amount: 1.57M | Year: 2016

The project STI International Cooperation Network for EaP Countries Plus (EaP PLUS) aims to stimulate cooperation between researchers from the EaP countries and EU MS and enhance the active participation of the Eastern Partnership countries in Horizon 2020 Framework Programme. Building on the results of the predecessor FP7 project IncoNet EaP, the project will eliminate remaining obstacles to EU-EaP STI cooperation through a number of innovative and targeted actions: (a) strategic priority setting through supporting EU-EaP policy dialogue and through maximizing the impact of the association to Horizon 2020; (b) stronger interaction between researchers & participation in H2020, i.e. Info days, cooperation with scientific diaspora, and grants for networking; (c) promotion of the research-innovation interface supporting communities of excellence, i.e. co-patenting analyses, clustering schemes, promotion of the technology platforms concept to EaP countries; (d) optimal framework conditions and increasing coordination in policies and programmes through training seminars for STI policymakers, increased coordination and synergies between policies and programmes of EU/MS and EaP, i.e. JPIs, COST, national programmes; (e) communication and outreach through innovative actions

Agency: European Commission | Branch: H2020 | Program: MSCA-RISE | Phase: MSCA-RISE-2016 | Award Amount: 684.00K | Year: 2017

The objective of the project is determination of universal features and specific properties of various systems spontaneously ordering into spatially inhomogeneous structures (mobile ions in solids, ionic liquid mixtures, soft-matter and biological systems), with special focus on effects of confinement. There is striking similarity between properties of the above systems despite different interactions and length scales of inhomogeneities. The fundamental relation between structural inhomogeneities and mechanical and thermodynamic properties is not fully understood because the exchange of knowledge between the solid-state, liquid-matter, soft-matter and biophysical communities is limited. Theoretical and simulation approaches developed by 3 EU MS \ 1 AC \ 2 TC groups are closely connected or complementary. We use mean-field, liquid-matter, DFT, integral equations, field and collective-variables theories, molecular simulation approaches, and experimental methods of electrochemistry. We will share our experience in constructing/modifying, solving and verifying experimentally models for different complex systems. The new results and theoretical approaches will help in future studies of various inhomogeneous systems. The first work package concerns systems spontaneously forming ordered patterns, from thin films on solid surfaces through particles on interfaces to biological membranes and arid ecosystems. The pattern formation can be exploited in innovative technology. In the second work package we will investigate ionic liquids/ionic-liquid mixtures, especially near charged surfaces and in porous media, and mobile ions in intercalation compounds. Mobile ions and ionic liquids in porous electrodes are potentially important in innovative electrochemistry. EU/TC knowledge transfer will be by joint theoretical, simulation and experimental studies. Open workshops will be organized. Long term visits of young researchers and joint supervision of PhD students are planned.

Agency: European Commission | Branch: H2020 | Program: MSCA-RISE | Phase: MSCA-RISE-2016 | Award Amount: 1.11M | Year: 2017

The proposal is devoted to a development of smart drug-vector nanostructures (DVNs) based on stimuli-responsive inorganic, hybrid inorgano-organic nanomatrices, and polymer nanocapsules bearing new pharmaceutically active compounds (PhACs) and synthetic derivatives of natural PhACs. The innovative idea is the DVNs can enter target cancer cell or protozoan parasite infected cell through receptor mediated endocytosis and interact with distinct compartments of the cellular secretory pathway. Owing to adaptive drug release in response to variations in pH and redox environment, the parasite growth or cancer cells proliferation will be suppressed. For this purpose, strongly international and interdisciplinary VAHVISTUS consortium is created. Thus, principal objective of the proposal is to strengthen the existing international collaborations between the Consortium Partners and to establish new long-lasting international and inter-sectoral ones, to provide knowledge sharing through exchanges of research and innovation staff, and to create an intercontinental network in the area of smart DVNs for adaptive delivery to target cells. 6 academic organisations and 1 industrial partner of the Consortium from 3 MS/AC and 3 TC will develop intense and continuous knowledge sharing by cross-fertilisation of ideas through international and intersectoral secondments of staff at different carrier stages. The exchanges are well balanced between ER and ESR, men and women. The Proposal implementation is divided into 7 Work packages. A multicultural creative environment within the VAHVISTUS will contribute to make research and innovation an attractive carrier. Communication and dissemination activities as well as exploitation of results will be crucial within the VAHVISTUS. The Project results will enhance the competitiveness of European pharmaceutical industry, health care, and higher education. A Summer school will be organised on Smart Nanocarriers for Adaptive Drug Delivery.

Agency: European Commission | Branch: H2020 | Program: CSA | Phase: MG-1.5-2016-2017 | Award Amount: 1.00M | Year: 2016

The overall aim of the AERO-UA project is to stimulate aviation research collaboration between the EU and Ukraine through strategic and targeted support. AERO-UA is focused solely on Ukraine, because the country has a huge aerospace potential but a low level of aviation research collaboration with the EU. Ukraines aerospace sector spans the full spectrum of systems and components development and production with OEMs, Tier 1 and 2 suppliers, aeroengine manufacturers, control systems manufacturers, R&D institutions, aeronautic universities, and SMEs. This is also reflected in the sectors important contributor to the countrys economy (e.g. aircraft production of 1,9 billion in 2011). Ukrainian aerospace organisations possess unique know-how that can help Europe address the challenges identified in the ACARE SRIA / Flightpath 2050 Report. Furthermore, following the signing of the Agreement for the Association of Ukraine to Horizon 2020 in March 2015, Ukrainian organisations are eligible to participate in Clean Sky 2 and H2020 Transport on the same funding terms as those from EU member states. Equally, genuine commercial opportunities exist for European aviation organisations to help modernise Ukraines aerospace sector. The AERO-UA project will achieve its overall aim via four high-level objectives: 1. Identifying the barriers to increased EU-UA aviation research collaboration; 2. Providing strategic support to EU-UA aviation research collaboration; 3. Supporting EU-UA aviation research knowledge transfer pilot projects; and 4. Organising awareness-raising and networking between EU-UA stakeholders. The AERO-UA consortium is comprised of key EU and UA aviation organisations that will implement WPs closely mapped to the high-level objectives. The consortium will be supported by an Advisory Board involving Airbus, DLR, Min. Education and Science of Ukraine, Ukrainian State Air Traffic Services Enterprise and retired Director of EADS Jean-Pierre Barthlemy.

Agency: European Commission | Branch: H2020 | Program: CSA | Phase: LCE-14-2015 | Award Amount: 1.63M | Year: 2016

The aim of the SEEMLA project is the reliable and sustainable exploitation of biomass from marginal lands (MagL), which are used neither for food nor feed production and are not posing an environmental threat. The main target groups are regional authorities and public or private owners of MagLs, who can provide knowledge on land availability and are responsible for managing these. Furthermore foresters, farmers and the civil society affected by transformation of MagL into energy crop plantations are important cooperation partners for the projects success. The initial challenge of the project is to define MagL. In order to achieve high yields on the MagL the goal is to develop and optimize cropping systems for special sites. The project focuses both on existing plantations of energy crops on MagL and on the establishment of new plantations on MagLs. General guidelines and manuals shall attract and help relevant stakeholders as well as piloting shall prove the feasibility of SEEMLA results. The first scenario will enable the assessment of good practice and the refinement of current practices, making them more sustainable (environmental, economic, social). The second approach will transfer good practices to underused MagL. The project will focus on three main objectives: the promotion of re-conversion of MagLs for the production of bioenergy through the direct involvement of farmers and foresters, the strengthening of local small scale supply chains and the promotion of plantations of bioenergy plants on MagLs. Moreover the expected impacts are: Increasing the production of bioenergy, farmers incomes, investments in new technologies and the design of new policy measures. The project team is balanced between scientific and technical partners as well as national and regional organisations. By including partners from South-East, Eastern and Central Europe the knowledge transfer between regions of different climatic and political backgrounds can be established.

A complete and exact solution of the ground-state problem for the Ising model on the Shastry-Sutherland lattice in an applied magnetic field is found. The magnetization plateau at one third of the saturation value is shown to be the only possible fractional plateau in this model. However, stripe magnetic structures with 1/2 and 1/n (n>3) magnetization, observed in the rare-earth-metal tetraborides RB 4, occur at the boundaries of the three-dimensional regions of the ground-state phase diagram. These structures give rise to new magnetization plateaus if interactions of longer range are taken into account. For instance, an additional third-neighbor interaction is shown to produce a 1/2 plateau. The results obtained significantly refine the understanding of the magnetization process in RB 4 compounds, especially in TmB 4 and ErB 4, which are strong Ising magnets. © 2012 American Physical Society.

Yesylevskyy S.O.,Ukrainian Academy of Sciences
PLoS computational biology | Year: 2010

Coarse-grained (CG) simulations have become an essential tool to study a large variety of biomolecular processes, exploring temporal and spatial scales inaccessible to traditional models of atomistic resolution. One of the major simplifications of CG models is the representation of the solvent, which is either implicit or modeled explicitly as a van der Waals particle. The effect of polarization, and thus a proper screening of interactions depending on the local environment, is absent. Given the important role of water as a ubiquitous solvent in biological systems, its treatment is crucial to the properties derived from simulation studies. Here, we parameterize a polarizable coarse-grained water model to be used in combination with the CG MARTINI force field. Using a three-bead model to represent four water molecules, we show that the orientational polarizability of real water can be effectively accounted for. This has the consequence that the dielectric screening of bulk water is reproduced. At the same time, we parameterized our new water model such that bulk water density and oil/water partitioning data remain at the same level of accuracy as for the standard MARTINI force field. We apply the new model to two cases for which current CG force fields are inadequate. First, we address the transport of ions across a lipid membrane. The computed potential of mean force shows that the ions now naturally feel the change in dielectric medium when moving from the high dielectric aqueous phase toward the low dielectric membrane interior. In the second application we consider the electroporation process of both an oil slab and a lipid bilayer. The electrostatic field drives the formation of water filled pores in both cases, following a similar mechanism as seen with atomistically detailed models.

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