Uberaba, Brazil
Uberaba, Brazil
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De Oliveira K.F.,Federal University of Triângulo Mineiro | Da Cunha D.F.,UFTM | Weffort V.R.S.,UFTM
Jornal de Pediatria | Year: 2011

Objectives: To assess adequacy of vitamin C intake in HIV-infected children and adolescents; to evaluate serum levels of vitamin C and indicators of oxidative stress; to compare with the uninfected group; to correlate serum vitamin C with oxidative stress and associate them according to the reference values. Methods: Comparative cross-sectional study. Two groups of 27 children and adolescents each, aged between 3 to 19 years. Group 1 (G1) comprised individuals vertically infected with HIV seen at a regional outpatient clinic. Group 2 (G2) comprised invited individuals without history of HIV infection. The groups were matched for age, sex, and socioeconomic status. The following variables were analyzed: body mass index for age; micronutrient intake and consumption; and serum vitamin C, C-reactive protein (CRP), and albumin. Results: The mean age was 12 years old. Most subjects were female (17, 63%), and there was prevalence of the economic class C (27, 50%). The most prevalent nutritional status was normal weight in 20 individuals (74.1%) in G1 and 21 (77.8%) in G2. The intake of vitamin C was significantly higher in G1 (p = 0.006; t = 2.987) according to the 24-hour dietary recall method. There were significant differences in serum vitamin C concentration between the groups, with a lower level in G1 (p = 0.000; t = -7.309). In relation to oxidative stress, values of CRP in G1 were significantly higher (p = 0.007; t = 2.958). There was no association between deficiency of vitamin, CRP, and albumin. Conclusion: Our findings show that HIV-infected individuals have low levels of vitamin C; however, this deficiency is not related to eating habits, since the intake of this nutrient was higher in this group than in the control group. HIV-infected individuals have specific characteristics that increase their oxidative stress, which is evidenced by increased CRP. Copyright © 2011 by Sociedade Brasileira de Pediatria.

Santos K.G.,UFTM | Ferreira L.V.,Federal University of Uberlandia | Santana R.C.,Federal University of Uberlandia | Barrozo M.A.S.,Federal University of Uberlandia
Materials Science Forum | Year: 2017

Spouted bed simulations are usually performed using only one granular phase with a mean particle diameter representing the entire particle mixture, instead of a particle size distribution. In this study, the effect of the particle size distribution is accounted through the simulation of a mixture with five granular phases. The results showed that the particle segregation occurs. Larger particles are more concentrated in the upper region, while the smaller particles are preferably positioned in the lower region of the bed. Computational simulation using CFD method reproduced well the segregation experiments with different participle sizes of sand. © 2017 Trans Tech Publications, Switzerland.

Borges B.A.F.,UFTM | Urias P.M.,UFTM | Barrozo M.A.S.,Federal University of Uberlandia | dos Santos K.G.,UFTM
Materials Science Forum | Year: 2017

In this work, it was done a series of analysis in different conditions of the pyrolysis process to verify the difference of the composition in each one of the final products. In the case of the slow pyrolysis the heating ratio varied among 1.5, 20, 40 e 50 °C/min, and analyzed for each of these rates the composition of the final product. For the case of the fast pyrolysis, the temperature varied among 350, 400, 450, 500, 550 °C, maintaining the other conditions of the process constant, in the end of the process analyzed the composition of the final product for each temperature. For the verification of the composition of these products, they were classified and separate in categories according to the functional group, and after that, the ones who had the most relevant quantities were more deeply analyses to verify some important characteristics and the main industry applications. After this, it was determined the ideals conditions of slow and fast pyrolysis. The resulting products were analyzed by gas chromatography/mass spectrometry. For slow pyrolysis, the heating rate of 40°C/min produced a diversified product, composed by the heterocyclics, levoglucosan, phenols and hydrocarbons. The fast pyrolysis produced mainly the heterocyclic compounds, levoglucosan, phenols and carboxylic acids, in temperatures between 450°C and 500°C. © 2017 Trans Tech Publications, Switzerland.

Araujo B.S.A.,UFTM | dos Santos K.G.,UFTM
Materials Science Forum | Year: 2017

Spout fluidized bed has shown promising for gas-solid contact operations with and without chemical reactions, such as drying, coating, granulation, gasification, pyrolysis, etc. This is because these beds combine features from both spouted and fluidized beds. The other point is the ability to treat chemical transformations involving both heat and mass transfer in combination with particles of various sizes. Therefore, it is extremely important the knowledge of fluid dynamic of the bed, mainly for scale-up projects, which makes computer simulation an essential tool. Researches using the Computation Fluid Dynamics (CFD) proved to be very effective in predicting of particles dynamic in this type of bed. In Computation Fluid Dynamics, the two phases are treated as interpenetration continuous, and these phases are described by equations of conservation of mass, momentum and energy. The goal of the present work was to simulate using CFD experimental fluid dynamics data of a spout fluidized bed. Eight distinct flow regimes were identified which showed up in good agreement with the regime map presented in literature. The results showed that the technique was efficient for the simulation of the hydrodynamic of the bed presented. © 2017 Trans Tech Publications, Switzerland.

Silva B.T.,UFTM | Santiago L.B.,University of Sao Paulo | Lamonier J.A.,Federal University of Minas Gerais
Revista Paulista de Pediatria | Year: 2012

Objective: To identify publications regarding the role of the father or partner in the breastfeeding practice. Data source: An integrative review of the literature was performed searching for articles published between 1995 and 2010, using the key-words "father" and "breastfeeding" in following databases: LILACS, SciELO, BDENF e PubMed/MEDLINE. Data were organized in three categories: the supporting role of the father on breastfeeding; paternal perceptions about breastfeeding; and the impact of educational intervention on breastfeeding for parents. Data synthesis: 44 articles showed that social, professional and family support is vital to successful breastfeeding. The father was highlighted as crucial supporter due to his strong influence over women ́s decision to breastfeed and to maintain breastfeeding. However, the involvement of the father presents evasive patterns: competition with the mother vs. protection, exclusion vs. increase strength in the family relationships, support vs. prejudices. Health professionals were reported as reference sources of education, however they were shown as unprepared to assist the parents. Conclusions: Several studies on the theme of paternal support were found in the literature, which highlights its importance for successful breastfeeding. However, most of the research had a descriptive approach and there were few studies on educational interventions.

Donizetti-Oliveira C.,Federal University of São Paulo | Semedo P.,Federal University of São Paulo | Burgos-Silva M.,Federal University of São Paulo | Cenedeze M.A.,Federal University of São Paulo | And 5 more authors.
Cell Transplantation | Year: 2012

Adipose tissue-derived stem cells (ASCs) are an attractive source of stem cells with regenerative properties that are similar to those of bone marrow stem cells. Here, we analyze the role of ASCs in reducing the progression of kidney fibrosis. Progressive renal fibrosis was achieved by unilateral clamping of the renal pedicle in mice for 1 h; after that, the kidney was reperfused immediately. Four hours after the surgery, 2 × 105 ASCs were intraperitoneally administered, and mice were followed for 24 h posttreatment and then at some other time interval for the next 6 weeks. Also, animals were treated with 2 × 105 ASCs at 6 weeks after reperfusion and sacrificed 4 weeks later to study their effect when interstitial fibrosis is already present. At 24 h after reperfusion, ASCtreated animals showed reduced renal dysfunction and enhanced regenerative tubular processes. Renal mRNA expression of IL-6 and TNF was decreased in ASC-treated animals, whereas IL-4, IL-10, and HO-1 expression increased despite a lack of ASCs in the kidneys as determined by SRY analysis. As expected, untreated kidneys shrank at 6 weeks, whereas the kidneys of ASC-treated animals remained normal in size, showed less collagen deposition, and decreased staining for FSP-1, type I collagen, and Hypoxyprobe. The renal protection seen in ASC-treated animals was followed by reduced serum levels of TNF-α, KC, RANTES, and IL-1α. Surprisingly, treatment with ASCs at 6 weeks, when animals already showed installed fibrosis, demonstrated amelioration of functional parameters, with less tissue fibrosis observed and reduced mRNA expression of type I collagen and vimentin. ASC therapy can improve functional parameters and reduce progression of renal fibrosis at early and later times after injury, mostly due to early modulation of the inflammatory response and to less hypoxia, thereby reducing the epithelial-mesenchymal transition. © 2012 Cognizant Comm. Corp.

Barroso S.M.,Federal University of Triângulo Mineiro | de Andrade V.S.,UFTM | Midgett A.H.,Boise University | de Carvalho R.G.N.,Federal University of Triângulo Mineiro
Jornal Brasileiro de Psiquiatria | Year: 2016

Objective: This study investigated the validity evidence of Loneliness Scale UCLA to be used in the Brazilian population. Methods: It was followed the phases authorization of the author and the Ethics Committee, translation and back-translation, semantic adaptation and validation of the test. Data were analyzed by descriptive analysis, exploratory factor, alpha Chronbach, Kappa, sphericity test of Bartlett, Kaiser-Meyer-Olkin test and Pearson’s correlation. To semantic adaptation the scale was submitted to specialists and a focus group with 8 participants and to cross-cultural adaptation the scale was submitted to a pilot study with 126 participants. In the validation participated 818 people, between 20 and 87 years, who responded to two versions of UCLA, Patient Health Questionnaire, Social Support Scale and a questionnaire made by the authors. Results: The scale showed two factors, which explained 56% of variance and alpha of 0.94. Conclusions: Loneliness Scale UCLA-BR indicated evidence of discriminant and construct validity, as well as good reliability. It can be used for evaluation of loneliness in the Brazilian population. © 2016, Editora Cientifica Nacional Ltda. All rights reserved.

Tribess S.,Federal University of Triângulo Mineiro | Virtuoso Jr. J.S.,UFTM | de Oliveira R.J.,University of Brasilia
Revista da Associacao Medica Brasileira | Year: 2012

Objective: To analyze physical activity in different domains (work, transportation, housework and leisure) as a predictor of the absence of frailty. Methods: An epidemiological cross-sectional study with a random sample of 622 individuals aged ≥ 60 years was carried out in Uberaba, MG, Brazil. Receiver operating characteristic (ROC) curves were generated and compared with physical activity in different domains and the absence of frailty. Cutoffs points of physical activity (minutes/week) were established to predict the absence of frailty. A confidence interval of 95% was established in order to find the largest areas under the ROC curves for work, transportation, household and leisure. The total physical activity and its domains were assessed by the international physical activity questionnaire. The index of frailty (unintentional weight loss, functional limitation to chair rise, handgrip strength, physical activity and exhaustion) was based on the study by Fried; the participants were dichotomously classified as not frail and frail. Results: The prevalence of frailty was 19.7% (men) and 20% (women). Physical activity of moderate or vigorous intensity accumulated in different domains for 145 minutes/week for women and 140 minutes/week for men or 85 minutes/week for women and 112.5 minutes/week for men for activities in the leisure domain showed the best cutoff to predict the absence of frailty. Conclusion: The practice of physical activity, especially in leisure time or accumulated in different domains, contributes to the prevention of frailty in the elderly. © 2012 Elsevier Editora Ltda. All right reserved.

Purpose: To evaluate the prevalence of testicular microlithiasis among pediatric patients with inguinoscrotal affections. Methods: Between January 2005 and January 2010, we evaluated, prospectively 1504 children ranging from 1 to 15 years with inguinoscrotal affections with a high-frequency ultrasound system, which employs a 10-MHz transducer. Results: Testicular microlithiasis was identified in 20 testes of eleven children (0.71% of 1504 patients evaluated), through an ultrasound scan. Testicular microlithiasis was found in 5 children with cryptorchidism (3.93% of 127 patients), 4 children with retractile testes (14.8% of 27 patients), 1 child with a hypotrophic testis (100% of 1 patient), and 1 child with inguinal hernia (0.07% of 1349 patients). The children with testicular microlithiasis were submitted to annual physical examinations and ultrasound evaluations. Conclusions: Testicular microlithiasis was a rare condition and occurred in 0.7% of the subjects studied. The association with cryptorchidism, retractile and hypotrophic testis was significant.

Objective: To review the literature on the importance of antioxidant vitamins, analyzed in the context of dietary intake, its plasma levels, and its current use as a supplementation treatment in obese children and adolescents with nonalcoholic fatty liver disease. Data sources: The articles were identified in Lilacs, Ibecs, SciELO, PubMed/Medline, and Scopus databases. To conduct the survey, the "fatty liver" descriptor was associated to the following words: "children", "antioxidants" and "vitamins". The search was limited to articles written in Portuguese, Spanish and English, with publication date until December, 2012. Data synthesis: Six studies were selected. The survey revealed a low dietary intake and low antioxidant vitamins serum levels in this population. The changes in lifestyle, with adequate dietary intake of vitamins, and the increase in physical activity were associated with a significant improvement in liver histology and in laboratory tests. Vitamin supplementation also improved the disease progression markers, as the alanine aminotransferase serum levels and the histological characteristics of lobular inflammation and hepatocellular damage. However, these improvements were not statistically significant in all studies. Conclusions: There is insufficient evidence to recommend or to refute antioxidant supplementation in patients with simple steatosis or steatohepatitis. The changes in lifestyle seem to be, at the present time, the more advisable therapy.

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