Morrisville, NC, United States
Morrisville, NC, United States

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Patent
TyraTech | Date: 2013-06-28

Embodiments of the invention relate to a pest-control composition comprising at least one active ingredient and at least two other ingredients; wherein the at least one active ingredient is selected from the group consisting of geraniol, nootketone, amyl cinnamaldehyde, catnip, wintergreen, carvacrol, d-limonene, orange oil, lauric acid, alpha pinene, mint, cornmint oil, lemon oil, eucalyptus, eugenol, peppermint, lemongrass oil, and terpenes; and wherein the at least two other ingredients are selected from the group consisting of 2-propanol, alcohol, ethanol, monobutyl ether, ethylene glycol, terpenes, ethoxylated alcohol, dodecanol, ammonia, soap, lauryl polyglucose, polyethylene glycol, sodium lauryl sulfate, sodium olefin sulfonate, cocamidapropyl betaine, alkylbenzene sulfonate, polyoxyethelene alkylphenol sulfate, sodium dodecyl benzene sulfonate, sodium sterate, potassium sterate, potassium myristate, tomadol, polyglyceryl sterate, glycol monosterate, potassium oleate, polyglyceryl oleate, tween, polymers, acrylic polymers, ethyl cellulous, carboxymethyl cellulose, sodium hydroxide, ammonium hydroxide, polyacrylate polymer, polyvinyl pyrolidane, lauric diethanolamine, dimethyldodecylamine oxide, aspartic acid tetrasodium salt, and sodium citrate.


Compositions for treating parasitic infections and methods of using the compositions to treat subjects with parasitic infections are provided. Methods of selecting compositions for use in treating parasitic infections are further provided.


A method of screening a composition for insect control activity, comprising: providing insect cells expressing at least one receptor chosen from tyramine receptor, Or83b olfactory receptor, and Or43a olfactory receptor; adding said composition to the cells; measuring the binding affinity of said composition to the tyramine receptor or the Or43a receptor or to any two of the tyramine receptor, the Or43a receptor, and the Or83b receptor, or to all three receptors; and selecting compositions having an affinity for the receptor or receptors.


Patent
TyraTech | Date: 2014-05-29

Embodiments of the present invention provide compositions for controlling a target pest including a pest control product and at least one active agent, wherein: the active agent can be capable of interacting with a receptor in the target pest; the pest control product can have a first activity against the target pest when applied without the active agent and the compositions can have a second activity against the target pest; and the second activity can be greater than the first activity.


Formulations of pesticides are disclosed, specifically pesticidal blends of essential oils and other ingredients, that have been found to enhance the activity of the active pesticidal ingredients. The formulations may be, for example, emulsions or dust formulations. For example, a composition for controlling a target pest is disclosed that comprises at least one active agent and a formulation agent, wherein: the active agent is capable of interacting with a receptor in the target pest; the active agent has a first activity against the target pest when applied without the formulation agent and the composition has a second activity against the target pest; and the second activity is greater than the first activity.


An exemplary method of screening compositions for insect control activity includes, providing an insect cell expressing a receptor of the insect olfactory cascade or fragment thereof, contacting a test composition to the insect cell, measuring at least one parameter selected from olfactory cascade receptor binding affinity, intracellular cAMP levels, and intracellular Ca^(2+ )levels, and selecting a compound capable of altering at least one of parameter selected from increased olfactory cascade receptor binding affinity, altered intracellular cAMP levels, and altered intracellular Ca^(2+ )levels. An exemplary isolated eukaryotic cell is transformed with a nucleic acid encoding an insect olfactory cascade receptor protein or fragment thereof. An exemplary method for controlling an insect includes, contacting a composition including a compound having a binding affinity for an olfactory cascade receptor of an insect.


Patent
TyraTech | Date: 2014-03-17

The present invention generally relates to compositions and methods related to controlling arthropods. Embodiments of the invention include compositions for controlling an arthropod, which can include one or more plant essential oils and methods for using these compositions. The plant essential oils, when combined, can have a synergistic effect. Embodiments of the invention relate to compositions and methods related to controlling lice.


Patent
TyraTech | Date: 2013-10-18

The present invention relates to compositions and methods related to controlling arthropods. Embodiments of the invention include compositions for controlling an arthropod, which can include one or more plant essential oils and methods for using these compositions. The plant essential oils, when combined, can have a synergistic effect.


Formulations of pesticides are disclosed, specifically pesticidal blends of essential oils and other ingredients, that have been found to enhance the activity of the active pesticidal ingredients. The formulations may be, for example, emulsions or dust formulations. For example, a composition for controlling a target pest is disclosed that comprises at least one active agent and a formulation agent, wherein: the active agent is capable of interacting with a receptor in the target pest; the active agent has a first activity against the target pest when applied without the formulation agent and the composition has as a second activity against the target pest; and the second activity is greater than the first activity.


Patent
TyraTech | Date: 2013-08-05

Compositions and methods for treating parasitic infections are provided. The compositions can include two or more of alpha-pinene, linalyl acetate, para-cymene, and thymol octanoate. The compositions and methods can be effective against, for example, protozoan parasites, helminthic parasites, nematodes, trematodes, flukes, cestodes, and the like. Formulations made from the composition are also provided, including formulations in which the composition is combined with a carrier to form a food product and/or a drink. The formulation can be, for example, a suspension, a solution, or an emulsion in an oily or an aqueous carrier; likewise, the composition can be provided in an encapsulated or microencapsulated form.

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