Demircelik M.B.,Ankara University |
Kurtul A.,Ankara Education and Research Hospital |
Ocek H.,Ankara Education and Research Hospital |
Cakmak M.,Turgut Ozal University |
And 2 more authors.
CardioRenal Medicine | Year: 2015
Objective: Contrast-induced nephropathy (CIN) is associated with significantly increased morbidity and mortality after percutaneous coronary intervention (PCI). Patients with acute coronary syndrome (ACS) are at higher risk of CIN. The platelet-to-lymphocyte ratio (PLR) is closely linked to inflammatory conditions. We hypothesized that PLR levels on admission can predict the development of CIN after PCI for ACS. Subjects and Methods: A total of 426 patients (mean age 63.17 ± 13.01 years, 61.2% males) with ACS undergoing PCI were enrolled in this study. Admission PLR levels were measured before PCI. Serum creatinine values were measured before and within 72 h after the administration of contrast agents. Patients were divided into 2 groups: the CIN group and the no-CIN group. CIN was defined as an increase in serum creatinine level of ≥0.5 mg/dl or 25% above baseline within 72 h after contrast administration. Results: CIN developed in 53 patients (15.9%). Baseline PLR was significantly higher in patients who developed CIN compared to those who did not (160.8 ± 29.7 and 135.1 ± 26.1, respectively; p < 0.001). Multivariate analyses found that PLR [odds ratio (OR) 3.453, 95% confidence interval (CI) 1.453-8.543; p = 0.004] and admission creatinine (OR 6.511, 95% CI 1.759-11.095; p = 0.002) were independent predictors of CIN. Conclusions: The admission PLR level is an independent predictor of the development of CIN after PCI in ACS. © 2015 S. Karger AG, Basel.
Yakut Z.I.,Ataturk Training and Research Hospital |
Karada R.,Istanbul Medeniyet University |
Ozol D.,Turgut Ozal University |
Senturk A.,Ataturk Training and Research Hospital
Journal of Investigative Medicine | Year: 2015
Purpose: Both chronic obstructive pulmonary disease (COPD) and asthma are important causes of morbidity and mortality worldwide. They primarily affect the lungs, but they have various extrapulmonary manifestations. The aim of our study was to evaluate the hemodynamic changes in orbital vessels of the patients with COPD and asthma using color Doppler ultrasonography and compare the results with healthy control subjects. Methods: Thirty-seven patients with COPD, 37 patients with asthma, and 41 healthy control subjects were included in this study. All patients with COPD were in moderate to severe group according to GOLD (Global Initiative for Chronic Obstructive Lung Disease), and similarly, all patients with asthma were in moderate to severe persistent group according to GINA (Global Initiative for Asthma) 2006 guidelines. Endtidal carbon dioxide, peripheral oxygen saturation, pulse rate, and respiratory rate were measured by using pulse oximeter in all patients. Measurements were performed in only 1 randomly selected eye of each participant. The peak systolic velocity, end diastolic velocity, and resistance index were measured in the central retinal artery, temporal posterior ciliary artery, and nasal posterior ciliary artery using the color Doppler ultrasonography technique. Results: The peak systolic velocity, end diastolic velocity, and resistance index values of temporal posterior ciliary artery and nasal posterior ciliary artery were significantly higher in COPD and asthma than in the control subjects. There was no difference between asthma and COPD. Conclusions: We concluded that retrobulbar hemodynamics change in COPD and asthma is showing 1 of the systemic effects in these diseases. © Copyright 2014 American Federation for Medical Research. Unauthorized reproduction of this article is prohibited.
Gunes A.,Meteksan Savunma Sanayii A.S. |
Bereketli A.,Meteksan Savunma Sanayii A.S. |
Guldogan M.B.,Turgut Ozal University
2014 22nd Signal Processing and Communications Applications Conference, SIU 2014 - Proceedings | Year: 2014
Underwater acoustic vector sensors (AVS) are devices which can measure scalar pressure and three dimensional acceleration or particle velocity with only one sensor. Bearing estimation for the target can be accomplished by these four measured scalar values. Algorithms based on closed-form expressions or beamforming can be carried out for direction finding by using the axial projections of the gradient vector of the pressure from the target. In this work, the performances of direction of arrival estimation algorithms for underwater acoustic vector sensors are analyzed in detail under the effects of various error sources such as imperfect projections and ambient noise. © 2014 IEEE.
Bilgic I.C.,Turgut Ozal University |
Gelecek S.,Ankara Numune Teaching and Research Hospital |
Ozmen M.M.,Hacettepe University |
Kasapoglu B.,Ankara University
Blood Coagulation and Fibrinolysis | Year: 2015
Mesenteric ischemia is a life-threatening vascular emergency with high mortality rates. Mean platelet volume (MPV) has been shown to be closely related to platelet activation. We investigated whether MPV was associated with outcome of acute mesenteric ischemia (AMI). Sixty-one patients who were operated for AMI were retrospectively evaluated. Patients were divided into two groups: survivors and nonsurvivors, according to the outcome, and the two groups were compared in terms of MPV levels and other prognostic factors. Urea, creatinine, alkaline phosphatase, amylase, gamma-glutamyl transferase and MPV levels were significantly higher in nonsurvivors, when compared to that of survivors. In addition, hypertension, atherosclerotic heart diseases and rhythm disorders were statistically significant risk factors for mortality. AMI is an uncommon but highly lethal surgical emergency. Our results indicate that an elevated MPV is associated with a worse outcome in patients with AMI. Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.
Ozcan R.,Turgut Ozal University |
Altingovde I.S.,Middle East Technical University |
Cambazoglu B.B.,Yahoo! |
Ulusoy O.R.,Bilkent University
ACM Transactions on the Web | Year: 2013
Web search engines are known to cache the results of previously issued queries. The stored results typically contain the document summaries and some data that is used to construct the final search result page returned to the user. An alternative strategy is to store in the cache only the result document IDs, which take much less space, allowing results of more queries to be cached. These two strategies lead to an interesting trade-off between the hit rate and the average query response latency. In this work, in order to exploit this trade-off, we propose a hybrid result caching strategy where a dynamic result cache is split into two sections: an HTML cache and a docID cache. Moreover, using a realistic cost model, we evaluate the performance of different result prefetching strategies for the proposed hybrid cache and the baseline HTML-only cache. Finally, we propose a machine learning approach to predict singleton queries, which occur only once in the query stream. We show that when the proposed hybrid result caching strategy is coupled with the singleton query predictor, the hit rate is further improved. © 2013 ACM.