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Dortmund, Germany

TU Dortmund University is a university in Dortmund, North Rhine-Westphalia, Germany with over 20,000 students, and over 3,000 staff. It is situated in the Ruhr area, the fourth largest urban area in Europe.The university is highly ranked in terms of its research performance in the areas of physics, electrical engineering, chemistry and economics. Wikipedia.


Spatial division multiplexing has been proposed as an option for further capacity increase of transmission fibers. Application of this concept is attractive only, if cost and energy efficient implementations can be found. In this work, optical amplification and optical filter based signal processing concepts are investigated. Deployment of multi mode fibers as the waveguide type for erbium doped fiber amplifiers potentially offers cost and energy efficiency advantages compared to using multi core fibers in preamplifier as well as booster stages. Additional advantages can be gained from optimization of the amplifier module design. Together with transponder design optimizations, they can increase the attractiveness of inverse spatial multiplexing, which is proposed as an intermediate step. Signal processing based on adaptive passive optical filters offers an alternative approach for the separation of channels at the receiver which have experienced mode coupling along the link. With this optical filter based approach, fiber capacity can potentially be increased faster and more energy efficiently than with solutions relying solely on electronic signal processing. © 2011 Optical Society of America. Source


Niemeyer C.M.,TU Dortmund
Angewandte Chemie - International Edition | Year: 2010

conjugation with artificial nucleic acids allows proteins to be modified with a synthetically accessible, robust tag. This attachment is addressable in a highly specific manner by means of molecular recognition events, such as Watson-Crick hybridization. Such DNAprotein conjugates, with their combined properties, have a broad range of applications, such as in high-performance biomedical diagnostic assays, fundamental research on molecular recognition, and the synthesis of DNA nanostructures. This Review surveys current approaches to generate DNA-protein conjugates as well as recent advances in their applications. For example, DNA-protein conjugates have been assembled into model systems for the investigation of catalytic cascade reactions and light-harvesting devices. Such hybrid conjugates are also used for the biofunctionalization of planar surfaces for micro- and nanoarrays, and for decorating inorganic nanoparticles to enable applications in sensing, materials science, and catalysis. © 2010 Wiley-VCH Verlag GmbH &. Co. KGaA,. Source


Patent
TU Dortmund and Heinrich Heine University Düsseldorf | Date: 2012-09-21

Provided is a host cell comprising a rhlA gene or an ortholog thereof, under the control of a heterologous promoter and a rhlB gene or an ortholog thereof, under the control of a heterologous promoter. The host cell is capable of achieving a carbon yield of more than 0.18 Cmol rhamnolipid/Cmol substrate. Provided is also a method of producing rhamnolipids, employing such a host cell.


Patent
TU Dortmund | Date: 2012-05-09

The invention relates to a method for the separation of a polarisable bioparticle comprising the steps: a) dielectrophoretic preseparation of a polarisable bioparticle from a suspension of bioparticles; b) fluidic separation of the selected bioparticle by fixing the bioparticle in a dielectrophoretic field cage and circulating fluid around the bioparticle; c) transferring the separated bioparticle from the dielectrophoretic field cage to a culture chamber; d) dielectrophoretic fixing of the separated bioparticle in the culture chamber and study, observation, manipulation and/or culturing of the separated bioparticle. The invention further relates to a microfluidic system and use thereof.


A method processes a stable emulsion having components from whole-cell biotransformations such as cells, soluble cell components, organic solvents and/or water. In this connection, the emulsion, which is stable after the biotransformation, is mixed with further parts of organic phase, and subsequently the mixture is continuously stirred until a catastrophic phase inversion of the emulsion takes place while mixing; subsequently, this phase-inverted mixture is transferred to a settling container, where the phases of the emulsion separate from one another and can be separated from one another.

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