The TU Braunschweig is the oldest University of Technology in Germany. It was founded in 1745 as Collegium Carolinum and is a member of TU9, an incorporated society of the most renowned and largest German Institutes of Technology. Wikipedia.
Merck Patent GmbH, The InnovationLAB, TU Braunschweig and Max Planck Gesellschaft Zur Foerderung Der Wissens chaften E.V. | Date: 2015-02-16
The present invention relates to a methoxyaryl surface modifier. In addition the present invention also relates to organic electronic devices comprising such methoxyaryl surface modifier.
Merck Patent Gmbh, The InnovationLAB, TU Braunschweig and Max Planck Gesellschaft Zur Foerderung Der Wissens Chaften E.V. | Date: 2015-02-16
The present invention relates to a cyclic amine surface modifier. In addition the present invention also relates to organic electronic devices comprising such cyclic amine surface modifier.
Agency: Cordis | Branch: H2020 | Program: RIA | Phase: MG-3.1-2016 | Award Amount: 6.64M | Year: 2016
SARAH is concerned with establishing novel holistic, simulation-based approaches to the analysis of aircraft ditching. It is build up from a consortium of experts from OEM industries, experienced suppliers of simulation technologies, established research institutions and representatives of the certification authorities. Results of SARAH are expected to support a performance-based regulation and certification for next generation aircraft and helicopter and to enhance the safe air transport as well as to foster the trustworthiness of aviation services. Aircrafts and helicopters often travel above water and thus have to prove a safe landing under emergency conditions. The specific challenge is to minimize the risk of injury to passengers and to enable safe evacuation. Accordingly, the motion of the aircraft/helicopter along with the forces acting on the structure are studied for controlled water impact during the design phase of an aircraft. Ditching has close links with crash simulation, but also distinctive features. Examples refer to hydrodynamic slamming loads on airborne vehicles and complex hydromechanics (partially at very large forward speeds) as well as the interaction of multi-phase fluid dynamics (involving air, water, and vapor phases) and structure mechanics. Design for ditching involves more than the analysis of loads and subsequent strengthening of the structure. It often requires adjustment campaigns for the handling of the vehicle during approach and the identification of favorable approach/flight-path conditions in line with the pilots flying capabilities to minimize the remaining kinetic energy of the vehicle to be transferred into the water. In conclusion, a pressing need for more advanced studies to support the development of next-generation, generalized simulation-based ditching-analysis practices is acknowledged by all stakeholders. The public interest in safety makes this proposal an ideal candidate for a European research proposal.
Agency: Cordis | Branch: H2020 | Program: RIA | Phase: ICT-06-2016 | Award Amount: 5.44M | Year: 2017
Fog computing brings cloud computing capabilities closer to the end-device and users, while enabling location-dependent resource allocation, low latency services, and extending significantly the IoT services portfolio as well as market and business opportunities in the cloud sector. With the number of devices exponentially growing globally, new cloud and fog models are expected to emerge, paving the way for shared, collaborative, extensible mobile, volatile and dynamic compute, storage and network infrastructure. When put together, cloud and fog computing create a new stack of resources, which we refer to as Fog-to-Cloud (F2C), creating the need for a new, open and coordinated management ecosystem. The mF2C proposal sets the goal of designing an open, secure, decentralized, multi-stakeholder management framework, including novel programming models, privacy and security, data storage techniques, service creation, brokerage solutions, SLA policies, and resource orchestration methods. The proposed framework is expected to set the foundations for a novel distributed system architecture, developing a proof-of-concept system and platform, to be tested and validated in real-world use cases, as envisioned by the industrial partners in the consortium with significant interest in rapid innovation in the cloud computing sector.
Agency: Cordis | Branch: H2020 | Program: RIA | Phase: FETOPEN-01-2016-2017 | Award Amount: 3.76M | Year: 2017
The physical laws of diffraction generally limit the spatial resolution of optical systems, being about 200 nm for light in the visible range. Within ChipScope we want to overcome this limit by developing the scientific and technological basis for a completely new approach to optical superresolution, based on semiconductor nano Light Emitting Diode (nanoLED) arrays with individual pixel operation. The core idea of ChipScope is to use spatially resolved illumination instead of spatially resolved detection for achieving microscopy functionality with superresolution. This will be made possible by developing chip-based nanoLED arrays with light emitting diode (LED) dimensions and distances much smaller than the wavelength of visible light (i.e. <50 nm). Thus, ChipScope will develop the highest resolution LED arrays in the world. These new devices will enable novel science in general and superresolution in particular. Making optical superresolution ubiquitously available is expected to lead to foundational breakthroughs in virtually every field of research and technology that makes use of optical microscopes. Within the project, the first chip-sized ChipScope microscopes will be developed, tested, calibrated and compared with state-of-the-art microscopy systems. During the course of the project, a game changing real-time imaging device for scientific investigation of living tissue will be used to study the in-cell mechanisms in Chronic Obstructive Pulmonary Disease (COPD) syndrome as a proof-of-concept of the new science and applications that will follow.
Agency: Cordis | Branch: H2020 | Program: IA | Phase: EeB-07-2015 | Award Amount: 6.89M | Year: 2016
The estimated average gap between calculated and actual energy performance of the European building stock is 25% for energy performance and 1,5% for comfort performance (as scored by building occupants). Comprehensive research has shown that faultily commissioned and operated building management systems are a main cause for this gap mainly caused by the lack of appropriate and coherent quality management systems for building performance. The objective of this project is therefore to develop and demonstrate pragmatic services and appropriate tools supporting quality management in the design, construction, commissioning and operation phase as a means to close this gap in European buildings. The project will integrate different innovative ICT-driven tools supporting the quality management process into building and energy services, and will apply them to a representative set of European buildings (taking into account different climate zones and different energy services). The result of this project will be a comprehensive QUANTUM quality management platform integrating tools, services and processes. The partners will implement EU-wide dissemination activities to inform the stakeholders about the advantages of comprehensive quality management systems for the building industry, and to promote the tools validated in the project. Stakeholders that will benefit from the results of this project include building owners, tenants, ESCOs, developers, architects, engineering and consulting firms, students and public authorities. Aside from savings on the energy costs CO2 emissions will be reduced and employee productivity in buildings equipped with the tools and services will increase as well due to increased occupant comfort. From previous preliminary data and own estimations, the QUANTUM partners expect that the reduction in energy consumption achieved by coherent quality management for building performance to be more than 10%.
Agency: Cordis | Branch: H2020 | Program: RIA | Phase: BES-04-2015 | Award Amount: 4.61M | Year: 2017
The last decades witnessed the ever growing effectiveness of Europe-subsidized border protection projects like SIVE and SIVICC. As maritime smuggling from Morocco towards the European borders of Portugal and Spain was combatted more effectively, the criminal modus operandi changed drastically, approaching air routes with cheap and small planes. New drone technology opens opportunity to both manned and unmanned airborne drug transports. Launched from any location and moving at low altitude and speed to mask their presence with the present clutter environment, drones can autonomously reach any landing site under nearly all circumstances. The ALFA system bridges this detection capability gap by drastically improving the situational awareness through the detection of LSS (Low, Small and Slow) manned and unmanned aircraft. ALFA is future-ready as technologies for drone detection will be a part of the system, which will use heterogeneous, easy-to-deploy mobile sensors based on several novel technologies. All sensor data, augmented by other existing sources of information, will be combined using evolved data fusion, providing accurate positional data for targets including eventual indication of the air vehicle type and reliable prediction of its landing site. This information will be communicated to the regional law enforcement units using a secure communication link and mobile device application, drastically improving the reaction time. Final ALFA capabilities will be demonstrated in a realistic operational context using relevant targets and in close cooperation with two principal end users taking part in the consortium. With their active participation, the ALFA system will make a significant contribution to the development of EUROSUR (in particular, cooperating with SIVE and SIVICC) and be suitable for a range of other missions and scenarios such as homeland and event protection and the protection of critical infrastructure.
Bohme K.,TU Braunschweig
PLoS pathogens | Year: 2012
Expression of all Yersinia pathogenicity factors encoded on the virulence plasmid, including the yop effector and the ysc type III secretion genes, is controlled by the transcriptional activator LcrF in response to temperature. Here, we show that a protein- and RNA-dependent hierarchy of thermosensors induce LcrF synthesis at body temperature. Thermally regulated transcription of lcrF is modest and mediated by the thermo-sensitive modulator YmoA, which represses transcription from a single promoter located far upstream of the yscW-lcrF operon at moderate temperatures. The transcriptional response is complemented by a second layer of temperature-control induced by a unique cis-acting RNA element located within the intergenic region of the yscW-lcrF transcript. Structure probing demonstrated that this region forms a secondary structure composed of two stemloops at 25°C. The second hairpin sequesters the lcrF ribosomal binding site by a stretch of four uracils. Opening of this structure was favored at 37°C and permitted ribosome binding at host body temperature. Our study further provides experimental evidence for the biological relevance of an RNA thermometer in an animal model. Following oral infections in mice, we found that two different Y. pseudotuberculosis patient isolates expressing a stabilized thermometer variant were strongly reduced in their ability to disseminate into the Peyer's patches, liver and spleen and have fully lost their lethality. Intriguingly, Yersinia strains with a destabilized version of the thermosensor were attenuated or exhibited a similar, but not a higher mortality. This illustrates that the RNA thermometer is the decisive control element providing just the appropriate amounts of LcrF protein for optimal infection efficiency.
Hopf H.,TU Braunschweig
Angewandte Chemie - International Edition | Year: 2013
Antimatter: Once studied primarily for their antiaromatic properties, pentalenes are rapidly becoming important π-systems for novel electronic materials (see scheme). Recent developments in this area are summarized. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Schroder U.,TU Braunschweig
Angewandte Chemie - International Edition | Year: 2012
Insects and molluscs as future biological drones for military purposes or environmental monitoring systems (see picture)? Two research groups have demonstrated the successful implantation and operation of biofuel cells in snails, clams, and cockroaches. Owing to their simple circulatory systems, these invertebrates could be used in implantation studies without serious physical damage. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.