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Salt Lake City, UT, United States

Talbott S.,Knoll Inc. | Talbott J.,Knoll Inc. | Christopulos A.-M.,Treehouse Athletic Club | Ekberg C.,Treehouse Athletic Club | And 2 more authors.
Progress in Nutrition

Chronic stress plays a major role in the pathophysiology of many disease states, particularly psychological disorders including depression, chronic fatigue syndrome, anxiety, fibromyalgia, and burnout. These stress-related changes in psychology may be due to both endocrine and behavioral factors - and may be mediated or attenuated by lifestyle factors including diet, exercise, and dietary supplements. Vigor is defined as a 3-tiered sustained mood-state that is characterized by (1) physical energy, (2) mental acuity, and (3) cognitive liveliness. Vigor can also be described as the opposite of "Burnout" (physical fatigue, mental exhaustion, and cognitive weariness). Our objective was to assess changes in Vigor, Mood State, and Metabolic Hormone Profile (cortisol and testosterone balance) in response to a modest lifestyle intervention including a dietary supplement based on traditional Asian medicine and including Eurycoma longifolia root, Citrus sinensis peel, and Camellia sinensis leaf - each of which is used in traditional Asian medicine to improve "life force" and well-being in fatigued individuals.We report on 82 subjects - all displaying moderate levels of psychological stress. We measured endocrine parameters [salivary cortisol to testosterone, (C:T) ratio)], and Global Mood State (MOOD) and related subscales: Vigor (V), Fatigue (F), and Depression (D), using the Profile of Mood States (POMS) psychological survey before and after the supplementation intervention. Subjects followed a supplementation periods of either 8-weeks or 12-weeks. Each intervention included recommendations to follow a balanced diet, moderate exercise, and daily supplementation. Compared to pre-supplementation values, post-supplementation measurements indicated significant changes for C:T ratio (-15-19%),MOOD (+20-22%), Vigor (+27-29%), Fatigue (-41-48%), and Depression (-40-52%). These data indicate that factors that are typically disrupted during periods of chronic stress (metabolic hormone profile and psychological mood state) may be positively and significantly impacted by modest changes in diet, exercise and supplementation patterns that mirror those commonly used in traditional Asian medicine. Source

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