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Jobby A.,Travancore Medical College
Journal of Indian Academy of Forensic Medicine | Year: 2014

Determination of age of an individual is one of the most important factors in establishment of identity. The present study was conducted on post-mortem specimens obtained from 100 males and 50 females above the age of 16 years in the population of North Kerala. The study used the phase evaluation chart to establish the age of an individual. In the male rib specimens, correct age could be predicted in 68% cases with evaluation of articular facet, firmness and texture combination. In the female rib specimen, it age could be estimated in 73% cases using firmness and shape of the rim combination. The results of the present study showed that it was a good method of assessment of age in a high percentage of cases even when only ribs are available. The method was very relevant at an application level when scattered bony remnants are obtained, to establish the identity in cases of mass disasters.


Chellamma P.,Travancore Medical College | Paramasivam S.,KAP Viswanatham Government Medical College | Thayyil J.,Government Medical College | Durairaj S.,Government Thiruvannamalai Medical CollegeTamil Nadu
Indian Journal of Public Health Research and Development | Year: 2016

Introduction: Scrub typhus is one of the reemerging Rickettsial diseases in India. The disease is spread to people by the bite of a mite infected with larval trombiculid mite. The objective of this study was to study the clinical profile and outcome of Scrub Typhus patients. Since scrub typhus was newly reported disease from this part of the country, the providers may not be familiar with the clinical pictures. Materials and Method: This study retrospectively reviewed the clinical records of patients admitted to government medical college, Kozhikode, a tertiary care centre in Kerala, during 2011 with positive Weil-Felix test and / or presence of eschar. Results: Thirty-two scrub typhus patients were admitted to the hospital during one year period (2011). Maximum number of patients were in the age group of 46-60 yrs. Major symptoms include fever(100%), headache(50%), myalgia (47%), vomiting(28%), cough(25%) and decreased urine output(22%), yellow coloured urine(15.6%) & breathlessness(12.5%). Eschar alone was present in a total of six patients(18.8%). Weil-Felix test alone was positive in a total of 25(78.1%) subjects. One patient had both eschar and Weil-Felix positivity. Common complications were ARDS(6/32), Meningoencephalitis(5/32), Myocarditis(4/32) Renal involvement and many patients developed multisystem involvement (6/32). One patient with multiorgan involvement died. Conclusion: Scrub typhus should be considered in the differential diagnosis of patients with acute febrile illnesses with a wide range of symptoms. Scrub typhus should be considered in the differential diagnosis of Leptospirosis, Typhoid, Dengue, Malaria. Empirical therapy with Doxycycline may be life-saving when clinical suspicion is high. © 2016, Indian Journal of Public Health Research and Development. All rights reserved.


Ahmed M.S.,Kannur Medical College | Neyaz A.N.,NIMS Medical College | Aslami A.,Travancore Medical College
Lung India | Year: 2016

Background: Chronic obstructive pulmonary disease (COPD) is characterized by airflow limitation that is not fully reversible. It is an incurable disease with improvement in quality of life (QOL) as a major focus area for management. This study assesses the QOL of COPD patients and the factors affecting it. Materials and Methods: All 124 patients diagnosed with COPD in a larger cross-sectional study to determine the prevalence of COPD were assessed for their QOL using St. George's respiratory questionnaire for COPD patients (SGRQ-C). Spirometry was performed to assess lung function and diagnose COPD. Chronic lung disease (CLD) severity index was used to assess the severity of symptoms and the Medical Research Council questionnaire was used to assess the severity of dyspnea. Sociodemographic data regarding the patients were also recorded. Results: Patients with COPD showed significantly reduced health-related quality of life (HRQOL). CLD estimate for severity of lung disease and the Medical Research Council assessment for dyspnea and the duration of illness showed a highly significant positive correlation with HRQOL. There was a statistically significant negative correlation between lung function and SGRQ-C score. Increasing age, increased quantum of smoking, and lower socioeconomic status were correlated with poorer HRQOL. No association between QOL and education, body mass index (BMI), and gender was observed. Conclusion: This study showed that Indian patients with COPD had reduced HRQOL. Poor lung function, increased disease duration and smoking, and worsening symptoms impacted HRQOL negatively. © 2016 Indian Chest Society.


Padmanabha B.V.,Jazan University | Taj S.,LIMSAR | Kumar S.S.,Travancore Medical College | Soumya M.,JIPMER | Antony N.J.,LIMSAR
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2015

The present study was undertaken to compare the clinical features and severity of ischemic stroke affecting various areas of brain using neuro-imaging techniques. Based on our results, we conclude that there is no association between aphasia and area of brain affected and no significant association between brain area and facial palsy however the association between type of hemiplegia and brain area involved and association between severities of stroke with hemisphere affected is significant. However small sample size constrains the significance of the results. Hence we recommend further study with higher sample size and long term follow up.


Vanagundi M.,Vijayanagar Institute of Medical science | Srinivasan P.K.,Travancore Medical College
Indian Journal of Public Health Research and Development | Year: 2013

Back ground: Smoking is now identified as a major cause of a wide variety of health problems. Much has been known about ill effects of smoking and tobacco use, but little about the beneficial effects following cessation of smoking habit. Hence this study intends to provide details regarding the same. Objective: To assess the improvement in pulmonary function of smokers after complete cessation of smoking at pre-determined time durations of about 4 weeks, 8 weeks & 12 weeks. Methodology: Study was conducted in Bengaluru on 55 healthy adult smokers presenting voluntary to undergo de-addiction. Their baseline FEV1, FVC, FEV1/FVC and PEF were recorded and repeated at various pre-determined intervals after onset of cessation program. Subjects were grouped into quitters and non-quitters based on maintenance of cessation. The results are compiled and statistically analyzed. Results and Conclusion: Following complete cessation of smoking habit, a definite improvement in all the above lung function parameters was seen. FEV1 improved by 394.14 mL (p<0.001), FVC improved by 335.45 mL (p<0.001), FEV1/FVC increased by 0.0412 (p=0.001) and PEF increased by 0.64 L/sec (p<0.001). The same parameters did not show significant change in non-quitters. The improvement in quitters showed inverse relationship with age and duration of smoking.


Aher C.S.,Travancore Medical College
Indian Journal of Public Health Research and Development | Year: 2014

Background: Members of the genus Acinetobacter are ubiquitous in the environment. For long, this organism was considered to be non-pathogenic. In recent years, organisms of the genus Acinetobacter have increasingly been associated with hospital infection. Objectives: To isolate and identify Acinetobacter species from cases suffering from urinary tract infection. To study the susceptibility of Acinetobacter calcoaceticus to various antibiotics Method: Study included microscopic examination, Gram stain study, culture and biochemical analysis of urine samples obtained from 200 patients admitted in the hospital, with clinically suspected urinary tract infection. Results: Acinetobacter was isolated from 5 (2.5%) urine samples from patients with urinary tract infection. Out of five isolates of Acinetobacter calcoaceticus, three were of var boumanni and two were of var lwoffi. Conclusion: Acinetobacter should be considered an important etiological agent for urinary tract infection. Special effort may be needed for isolation and identification of this organism. But it is worthwhile, considering its ubiquitous distribution, multiple portals of entry and tendency to develop multi-drug resistance. © 2014, Indian Journal of Public Health Research and Development. All rights reserved.


Lipin S.P.,Travancore Medical College | Paul B.,Travancore Medical College | Nazimudeen E.,Travancore Medical College | Jacob B.S.,Travancore Medical College
Journal of Association of Physicians of India | Year: 2012

Cronkhite-Canada syndrome (CCS) is a rare nonfamilial syndrome characterized by marked epithelial disturbances in the GI tract and epidermis. Cronkhite and Canada described the first 2 cases in 1955. Since then only about 450 cases have been reported worldwide. Here we report a 33 year old Indian male admitted with history of loose stools and abdominal pain, loose stools associated with weight loss, generalized weakness, significant amount of hair loss as well as hyperpigmentation of his palms and soles. On subsequent days of the stay in the hospital he developed hypogeusia and showed onychodystrophy. Endoscopy of Upper GI and Lower GI tract revealed severe gastroduodenitis with polyp in duodenum and multiple polyps whole throughout the colon respectively. Biopsy report showed eosinophilic gastritis and hamartomatous polyps in colon as well as in duodenum. He was started on high protein supplement, proton pump inhibitors and zinc-vitamin supplement and he showed a complete recovery in symptoms within 5 months of initiation of treatment. Hence, early diagnosis and initiation of appropriate treatment helped the patient to improve in symptoms from such a rare disease. © JAPI.


Aslami A.N.,Travancore Medical College | Jobby A.,Travancore Medical College | Nelson V.,Travancore Medical College | Simon S.,Travancore Medical College
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2015

Hypertension is one of the major public health issues in World today. In Kerala, the prevalence of hypertension is increasing rapidly due to several factors including fast life style and longevity. The objective of this study was to find out the prevalence of hypertension in a fishermen colony of Jonakapuram, Kollam, Kerala. A community based cross sectional study was conducted in the field practice area of Urban Health Training Centre of a Medical College. 985 study subjects aged 19 years and above were selected for the study. The study period was from January 2013 to December 2013. A house to house survey was conducted by using systematic random sampling. Percentiles, chi square test and multiple logistic regression was done on SPSS Software version 12. The prevalence of hypertension was 28.02% and it was significantly more in females as compared to males. The factors associated with hypertension were age, body mass index, additional salt intake, smoking, alcohol consumption and diabetes mellitus. 71.74% study subjects were aware about their hypertensive status and about 61.59% were on antihypertensive medication. The prevalence of hypertension in Jonakapuram is slightly high as compared to national average. A community based 'high risk screening' program to prevent the modern epidemic of chronic NCD's like hypertension is necessary.


PubMed | Travancore Medical College
Type: | Journal: The Journal of the Association of Physicians of India | Year: 2012

Cronkhite-Canada syndrome (CCS) is a rare nonfamilial syndrome characterized by marked epithelial disturbances in the GI tract and epidermis. Cronkhite and Canada described the first 2 cases in 1955. Since then only about 450 cases have been reported worldwide. Here we report a 33 year old Indian male admitted with history of loose stools and abdominal pain, loose stools associated with weight loss, generalized weakness, significant amount of hair loss as well as hyperpigmentation of his palms and soles. On subsequent days of the stay in the hospital he developed hypogeusia and showed onychodystrophy. Endoscopy of Upper GI and Lower GI tract revealed severe gastroduodenitis with polyp in duodenum and multiple polyps whole throughout the colon respectively. Biopsy report showed eosinophilic gastritis and hamartomatous polyps in colon as well as in duodenum. He was started on high protein supplement, proton pump inhibitors and zinc-vitamin supplement and he showed a complete recovery in symptoms within 5 months of initiation of treatment. Hence, early diagnosis and initiation of appropriate treatment helped the patient to improve in symptoms from such a rare disease.


PubMed | Travancore Medical College
Type: Journal Article | Journal: Nepal journal of epidemiology | Year: 2016

Hypertension is an important underline cause for cardiovascular deaths worldwide. Treatment compliance for hypertension depends on a lot of factors. There is paucity of studies about awareness and compliance to antihypertensive treatment particularly in coastal areas. Our aim was to know the awareness, treatment, compliance and control of blood pressure among hypertensive patients in a fishermen colony of Jonakapuram, Kollam.A community based cross sectional study was done in a coastal area of Kollam. A house-to-house survey was conducted with a pretested semi-structure questionnaire. Three blood pressure readings were taken and mean value was calculated. The study period was one year. Data was analyzed by using Statistical Package of Social Sciences 12. Appropriate statistical tests were applied.A total of 276 persons were found to be hypertensive. The percentage of awareness, treatment among aware subjects, treatment compliance and control of BP among patients taking anti-hypertensives was 71.74%, 85.86%, 73.53% and 50.58%. The awareness and treatment was significantly more among females as compared to males. The advices received by the patients were medicines, diet restrictions and lifestyle changes. Financial problems were the main reason for non-compliance to medicines.Nearly 3/4(th) of the study subjects were aware that they have hypertension. Monetary problems were an important cause for non-compliance. Half of the patients taking antihypertensive medication had their blood pressure uncontrolled. Patients economic status should be considered before advising them medications. This will increase compliance and help in improving the quality of patient care.

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