Traunkreis Vet Clinic

Sattledt, Austria

Traunkreis Vet Clinic

Sattledt, Austria
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Streitberger A.,Traunkreis Vet Clinic | Hocke V.,Traunkreis Vet Clinic | Modler P.,Traunkreis Vet Clinic
Journal of Veterinary Cardiology | Year: 2013

Objective To evaluate the feasibility of measuring pulmonary transit time (PTT) in healthy cats by transthoracic echocardiography using the ultrasound contrast agent Sonovue®. To determine normalized PTT (nPTT) values in 42 healthy cats and to estimate the interobserver variability and the within-day repeatability of nPTT measurements. Animals Forty-two privately owned healthy cats of different breeds, gender and age presented for cardiac examination. Methods A bolus injection of contrast agent (Sonovue®) was administered intravenously. The right parasternal short axis echocardiographic view was used to record the contrast agent's transit time from the pulmonary artery to the left atrium. Pulmonary transit time and nPTT were determined independently by three examiners with different levels of experience. Results Normalized PTT was 4.12 ± 1.0 (mean ± SD) in our population. The median interobserver variability across our population was 6.8%, the median within-day variability for the three observers were 13.1%, 12.7% and 13%. No effect of the observer's experience on nPTT measurement was identified. Age, sex and body weight did not significantly influence nPTT. Conclusions This study demonstrates that nPTT measurement is feasible in cats using ultrasound and the blood pool contrast media Sonovue®. Measurements of nPTT can be performed in a clinical setting. Normalized PTT values in healthy cats are comparable with those reported in healthy dogs. © 2013 Elsevier B.V. All rights reserved.


Streitberger A.,Traunkreis Vet Clinic | Modler P.,Traunkreis Vet Clinic | Haggstrom J.,Swedish University of Agricultural Sciences
Journal of Veterinary Cardiology | Year: 2015

Objectives To estimate heart rate-normalized pulmonary transit times (nPTTs) in cardiomyopathic cats with or without congestive heart failure (CHF). To assess potential associations of echocardiographic variables and nPTT and to evaluate nPTT as a test for the presence of CHF. Animals Forty-eight privately owned cats. Methods nPTT was measured using echocardiography and the ultrasound contrast media SonoVue® in 3 groups of cats: healthy cats (group 1), cats with cardiomyopathy (CM) but without CHF (group 2), and cats with CM and CHF (group 3). Interrelations between pulmonary blood volume (PBV), nPTT, stroke volume (SV), and echocardiographic variables were investigated by means of linear univariate and multivariate analysis. Results Median nPTT values in group 1, group 2, and group 3 were 3.63 (interquartile range [IQR], 3.20-4.22), 6.09 (IQR, 5.0-7.02), and 8.49 (IQR, 7.58-11.04), respectively. Values were significantly different between all 3 groups. Median PBVs in group 1, group 2, and group 3 were 27.94 mL (IQR, 21.02-33.17 mL), 42.83 mL (IQR, 38.46-50.36 mL) and 49.48 mL (IQR, 38.84-64.39 mL). SV, PBV, and shortening fraction <30% were significant predictors of nPTT. nPTT and left atrial to aortic root (LA:AO) ratio, not SV, were the main predictors of PBV. Conclusion nPTT may be useful as a test for the presence of CHF in cats with CM and as a measure of cardiac performance. nPTT and LA:AO ratios predict CHF with equal accuracy. Increased PBV is significantly associated with higher nPTT and LA:AO ratios. © 2015 Elsevier B.V.


PubMed | Traunkreis Vet Clinic and University of Veterinary Medicine Vienna
Type: Journal Article | Journal: Veterinary research | Year: 2017

In 2013, several Austrian piglet-producing farms recorded outbreaks of action-related repetitive myoclonia in newborn piglets (shaking piglets). Malnutrition was seen in numerous piglets as a complication of this tremor syndrome. Overall piglet mortality was increased and the number of weaned piglets per sow decreased by more than 10% due to this outbreak. Histological examination of the CNS of affected piglets revealed moderate hypomyelination of the white substance in cerebellum and spinal cord. We detected a recently discovered pestivirus, termed atypical porcine pestivirus (APPV) in all these cases by RT-PCR. A genomic sequence and seven partial sequences were determined and revealed a 90% identity to the US APPV sequences and 92% identity to German sequences. In confirmation with previous reports, APPV genomes were identified in different body fluids and tissues including the CNS of diseased piglets. APPV could be isolated from a shaking piglet, which was incapable of consuming colostrum, and passaged on different porcine cells at very low titers. To assess the antibody response a blocking ELISA was developed targeting NS3. APPV specific antibodies were identified in sows and in PCR positive piglets affected by congenital tremor (CT). APPV genomes were detected continuously in piglets that gradually recovered from CT, while the antibody titers decreased over a 12-week interval, pointing towards maternally transmitted antibodies. High viral loads were detectable by qRT-PCR in saliva and semen of infected young adults indicating a persistent infection.


PubMed | Traunkreis Vet Clinic
Type: Journal Article | Journal: Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology | Year: 2013

To evaluate the feasibility of measuring pulmonary transit time (PTT) in healthy cats by transthoracic echocardiography using the ultrasound contrast agent Sonovue(). To determine normalized PTT (nPTT) values in 42 healthy cats and to estimate the interobserver variability and the within-day repeatability of nPTT measurements.Forty-two privately owned healthy cats of different breeds, gender and age presented for cardiac examination.A bolus injection of contrast agent (Sonovue()) was administered intravenously. The right parasternal short axis echocardiographic view was used to record the contrast agents transit time from the pulmonary artery to the left atrium. Pulmonary transit time and nPTT were determined independently by three examiners with different levels of experience.Normalized PTT was 4.12 1.0 (mean SD) in our population. The median interobserver variability across our population was 6.8%, the median within-day variability for the three observers were 13.1%, 12.7% and 13%. No effect of the observers experience on nPTT measurement was identified. Age, sex and body weight did not significantly influence nPTT.This study demonstrates that nPTT measurement is feasible in cats using ultrasound and the blood pool contrast media Sonovue(). Measurements of nPTT can be performed in a clinical setting. Normalized PTT values in healthy cats are comparable with those reported in healthy dogs.


PubMed | Traunkreis Vet Clinic and Swedish University of Agricultural Sciences
Type: Journal Article | Journal: Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology | Year: 2015

To estimate heart rate-normalized pulmonary transit times (nPTTs) in cardiomyopathic cats with or without congestive heart failure (CHF). To assess potential associations of echocardiographic variables and nPTT and to evaluate nPTT as a test for the presence of CHF.Forty-eight privately owned cats.nPTT was measured using echocardiography and the ultrasound contrast media SonoVue() in 3 groups of cats: healthy cats (group 1), cats with cardiomyopathy (CM) but without CHF (group 2), and cats with CM and CHF (group 3). Interrelations between pulmonary blood volume (PBV), nPTT, stroke volume (SV), and echocardiographic variables were investigated by means of linear univariate and multivariate analysis.Median nPTT values in group 1, group 2, and group 3 were 3.63 (interquartile range [IQR], 3.20-4.22), 6.09 (IQR, 5.0-7.02), and 8.49 (IQR, 7.58-11.04), respectively. Values were significantly different between all 3 groups. Median PBVs in group 1, group 2, and group 3 were 27.94mL (IQR, 21.02-33.17mL), 42.83mL (IQR, 38.46-50.36mL) and 49.48mL (IQR, 38.84-64.39mL). SV, PBV, and shortening fraction <30% were significant predictors of nPTT. nPTT and left atrial to aortic root (LA:AO) ratio, not SV, were the main predictors of PBV.nPTT may be useful as a test for the presence of CHF in cats with CM and as a measure of cardiac performance. nPTT and LA:AO ratios predict CHF with equal accuracy. Increased PBV is significantly associated with higher nPTT and LA:AO ratios.

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