Touliu, Taiwan
Touliu, Taiwan

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Yeh D.-Y.,Transworld University | Cheng C.-H.,National Yunlin University of Science and Technology | Cheng C.-H.,123 University Road | Chen Y.-W.,National Yunlin University of Science and Technology
Expert Systems with Applications | Year: 2011

Cerebrovascular disease has been ranked the second or third of top 10 death causes in Taiwan and has caused about 13,000 people death every year since 1986. Once cerebrovascular disease occurs, it not only leads to huge cost of medical care, but even death. All developed countries in the world put cerebrovascular disease prevention and treatment in high priority, and invested considerable budget and human resource in long-term studies, in order to reduce the heavy burden. As the pathogenesis of cerebrovascular disease is complex and variable, it is hard to make accurate diagnosis in advance. However, in perspective of preventive medicine, it is necessary to build a predictive model to enhance the accurate diagnosis of cerebrovascular disease. Therefore, coupled with the 2007 cerebrovascular disease prevention and treatment program of a regional teaching hospital in Taiwan, this study aimed to apply the classification technology to construct an optimum cerebrovascular disease predictive model. From this predictive model, cerebrovascular disease classification rules were extracted and used to improve the diagnosis and prediction of cerebrovascular disease. This study acquired 493 valid samples from this cerebrovascular disease prevention and treatment program, and adopted three classification algorithms, decision tree, Bayesian classifier and back propagation neural network, to construct classification models, respectively. After analyzing and comparing classification efficiencies - sensitivity and accuracy, the decision tree constructed model was chosen as the optimum predictive model for cerebrovascular disease. In this model, the sensitivity and accuracy were 99.48% and 99.59%, respectively, and eight important influence factors of predicting cerebrovascular disease and 16 diagnosis classification rules were extracted. Five experienced cerebrovascular doctors assessed these rules, and confirmed them to be useful to the current clinical medical condition. © 2011 Elsevier Ltd. All rights reserved.


Ting W.T.E.,Purdue University Calumet | Yuan S.Y.,Transworld University | Wu S.D.,Soochow University of Taiwan | Chang B.V.,Soochow University of Taiwan
International Biodeterioration and Biodegradation | Year: 2011

Biodegradation of two polycyclic aromatic hydrocarbons (PAHs), phenanthrene and pyrene, by a white rot fungus, Ganoderma lucidum, in broth cultures was investigated. It was found that the biomass of the organism decreased with the increase of PAH concentration in the cultures. In the cultures with 2 to 50mgl -1 PAHs, the degradation rate constants (k 1) increased with the PAH concentration, whereas, at the level of 100mgl -1, the degradation rate constants decreased. In the presence of 20mgl -1 PAHs, the highest degradation rates of both PAHs occurred in cultures with an initial pH of 4.0 at 30°C. The addition of CuSO 4, citric acid, gallic acid, tartaric acid, veratryl alcohol, guaiacol, 2,2′-azino-bis-(3- ethylbenzothazoline-6-sulfonate) (ABTS) enhanced the degradation of both PAHs and laccase activities; whereas the supplement of oxalate, di-n-butyl phthalate (DBP), and nonylphenol (NP) decreased the degradation of both PAHs and inhibited laccase production. In conclusion, G. lucidum is a promising white rot fungus to degrade PAHs such as phenanthrene and pyrene in the environment. © 2010 Elsevier Ltd.


Yuan S.-Y.,Transworld University | Huang I.-C.,Soochow University of Taiwan | Chang B.-V.,Soochow University of Taiwan
Journal of Hazardous Materials | Year: 2010

In this study, we investigated the microbial degradation of the phthalate esters (PAEs) dibutyl phthalate (DBP) and di-(2-ethylhexyl) phthalate (DEHP), and change in microbial communities in mangrove sediment collected from 5 sampling sites along the Tanshui River in Taiwan. Aerobic degradation half-lives (t1/2) of DBP and DEHP ranged from 1.6 to 2.9d and 5.0 to 8.3d, respectively. The addition of yeast extract (5mg/L), hydrogen peroxide (1mg/L), brij 35 (91μM), humic acid (0.5g/L), cellulose (0.96mg/L), and sodium chloride (1%) enhanced PAE aerobic degradation. Sediment samples were separated into fractions with various particle size ranges from 0.1-0.45 to 500-2000μm. Sediment fractions with smaller particle sizes demonstrated higher PAE biodegradation rates. Of the microorganism strains isolated from the mangrove sediment, strains J2, J4, and J8 (all identified as Bacillus sp.) expressed the best biodegrading ability. Our results showed that Bacillus sp. was the dominant bacteria in the process of PAE aerobic degradation in the mangrove sediments. © 2010 Elsevier B.V.


The objective of this study is to examine the influences of heat loss characterized by a percentage of fuel's energy, friction and variable specific heats of working fluid on the performance of an air standard Diesel cycle with the restriction of maximum cycle temperature. A more realistic and precise relationship between the fuel's chemical energy and the heat leakage that is constituted on a pair of inequalities is derived through the resulting temperature. The variations in power output and thermal efficiency with compression ratio, and the relations between the power output and the thermal efficiency of the cycle are presented. The results show that the power output as well as the efficiency where maximum power output occurs will increase with the increase of maximum cycle temperature. The temperature-dependent specific heats of working fluid have a significant influence on the performance. The power output and the working range of the cycle increase while the efficiency decreases with increasing specific heats of working fluid. The friction loss has a negative effect on the performance. Therefore, the power output and efficiency of the cycle decrease with increasing friction loss. It is noteworthy that the effects of heat loss characterized by a percentage of fuel's energy, friction and variable specific heats of working fluid on the performance of a Diesel-cycle engine are significant and should be considered in practice cycle analysis. The results obtained in the present study are of importance to provide a good guidance for the performance evaluation and improvement of practical Diesel engines.


Yuan S.Y.,Transworld University | Chen S.J.,Soochow University of Taiwan | Chang B.V.,Soochow University of Taiwan
International Biodeterioration and Biodegradation | Year: 2011

This study investigated the anaerobic degradation of tetrachlorobisphenol-A (TCBPA) in sediment samples collected at three sites along the Erren River in southern Taiwan. TCBPA anaerobic degradation half-lives (t 1/2) in the sediment were 12.6, 16.9 and 21.7 d at concentrations of 50, 100, and 250μgg -1, respectively. TCBPA (50μgg -1) anaerobic degradation half-lives (t 1/2) in the sediment were 10.1, 11.8, 11.0, 11.6, 10.8, 9.1, 8.5, 18.2, 19.3, and 16.1 d by the addition of yeast extract (5mgl -1), cellulose (0.96mgl -1), sodium chloride (1%), brij 30 (130mgl -1), brij 35 (43mgl -1), rhamnolipid (55μM), surfactin (91μM), phthalic esters (2mgl -1), nonylphenol (2mgl -1), and heavy metals (2mgl -1), respectively. The degradation rate of TCBPA was enhanced by the addition of yeast extract, cellulose, sodium chloride, brij 30, brij 35, rhamnolipid, or surfactin. However, it was inhibited by the addition of phthalic esters, nonylphenol, or heavy metals. Also noted was the presence of dichlorobisphenol-A and bisphenol-A, two intermediate products resulting from the anaerobic degradation of TCBPA accumulated in the sediments. © 2010 Elsevier Ltd.


Tsai C.-F.,TransWorld University | Hsu Y.-W.,Chung Shan Medical University | Ting H.-C.,TransWorld University | Huang C.-F.,Chia Medical University | Yen C.-C.,Chung Shan Medical University
Food Chemistry | Year: 2013

The in vivo antioxidant and antifibrotic properties of green tea (Camellia sinensis, Theaceae) were investigated with a study of carbon tetrachloride (CCl4)-induced oxidative stress and hepatic fibrosis in male ICR mice. Oral administration of green tea extract at doses of 125, 625 and 1250 mg/kg for 8 weeks significantly reduced (p < 0.05) the levels of thiobarbituric acid-reactive substances (TBARS) and protein carbonyls in the liver by at least 28% compared with that was induced by CCl4 (1 mL/kg) in mice. Moreover, green tea extract administration significantly increased (p < 0.05) the activities of catalase, glutathione peroxidase (GSH-Px) and glutathione reductase (GSH-Rd) in the liver. Our study found that oral administration of green tea extract prevented CCl4-induced hepatic fibrosis, as evidenced by a decreased hydroxyproline level in the liver and a reduced incidence of hepatic fibrosis by histological observations. These results indicate that green tea exhibits potent protective effects against CCl4-induced oxidative stress and hepatic fibrosis in mice by inhibiting oxidative damage and increasing antioxidant enzyme activities. © 2012 Elsevier Ltd. All rights reserved.


Chen M.-H.,Chung Shan Medical University | Tsai C.-F.,TransWorld University | Hsu Y.-W.,Chung Shan Medical University | Lu F.-J.,Chung Shan Medical University
Molecular Vision | Year: 2014

Purpose: Ultraviolet B (UVB) radiation from sunlight is a known risk factor for human corneal injury. The aim of the present study was to investigate the protective effects of green tea polyphenol epigallocatechin gallate (EGCG) on UVB radiation-induced corneal oxidative damage in male imprinting control region (ICR) mice. Methods: Corneal oxidative damage was induced by exposure to UVB radiation at 560 μW/cm2. The animals received 0%, 0.1%, and 0.01% EGCG eye drops at a 5 mg/ml dose, twice daily for 8 days. Corneal surface damage was graded according to smoothness and the extent of lissamine green staining. Corneal glutathione (GSH), thiobarbituric acid-reactive substances (TBARS), and protein carbonyl levels, as well as superoxide dismutase (SOD), catalase, glutathione peroxidase (GSH-Px), and glutathione reductase (GSH-Rd) activity in the cornea, were measured to monitor corneal injury. Results: UVB radiation caused significant damage to the corneas, including apparent corneal ulceration and severe epithelial exfoliation, leading to a decrease in SOD, catalase, GSH-Px, GSH-Rd, and GSH activity in the cornea. However, the corneal TBARS and protein carbonyls increased compared with the control group. Treatment with EGCG eye drops significantly (p<0.05) ameliorated corneal damage, increased SOD, catalase, GSH-Px, GSH-Rd, and GSH activity, and decreased the TBARS and protein carbonyls in the corneas compared with the UVB-treated group. Conclusions: EGCG eye drops exhibit potent protective effects on UVB radiation-induced corneal oxidative damage in mice, likely due to the increase in antioxidant defense system activity and the inhibition of lipid peroxidation and protein oxidation. © 2014 Molecular Vision.


With changes in the environment and a rise of consciousness concerning environmental protection, industry has begun to devote research and develop into products which reflect the needs for environmental preservation as well as allow them to maintain their market share and competitive advantage. This study summarizes the impact of 24 elements of the R&D of new products in Taiwan's consumer electronics industry through factor analysis of a practical survey given to those in this industry. Factor analysis extracted four separate factors that speak to the potential for new product development. These factors are as follows: the potential for new product development, identifying the favorable internal and external factors to bolster competitiveness, the capability for R&D mastery and consumer acceptance preferences. This study calculates the corresponding weights of each factor and then proceeds with fuzzy multiple attribute decision making (FMADM) directed at green product development projects possessing the four factors stated in relation to their corresponding weights and finally compares these results with the product development project prescribed by application of the checklist evaluation model. The results prove that FMADM not only reaches the same conclusions as the policy-making checklist but also takes fuzzy uncertainty into account, giving a reflection of the real-world situation. © 2011 Elsevier Ltd. All rights reserved.


Tsai C.-F.,TransWorld University | Lu F.-J.,Chung Shan Medical University | Hsu Y.-W.,Chung Shan Medical University
Molecular Vision | Year: 2012

Purpose: Ultraviolet B (UVB) radiation from sunlight is known to be a risk factor for human corneal damage. The purpose of this study was to investigate the protective effects of Dunaliella salina (D. salina) on UVB radiation-induced corneal oxidative damage in male imprinting control region (ICR) mice. Methods: Corneal oxidative damage was induced by exposure to UVB radiation at 560 μW/cm 2. Animals were orally administered (gavage) D. salina at doses of 0, 123, and 615 mg/kg bodyweight/day for eight days. Corneal surface damages were graded according to smoothness and the extent of lissamine green staining. Corneal glutathione (GSH) and malondialdehyde (MDA) levels, as well as the activities of superoxide dismutase (SOD), catalase, glutathione peroxidase (GSH-Px), and glutathione reductase (GSH-Rd) in cornea were measured to monitor corneal injury. Results: UVB irradiation caused significant damage to the corneas, including apparent corneal ulcer and severe epithelial exfoliation, leading to decrease in the activities of SOD, catalase, GSH-Px, GSH-Rd, and GSH content in cornea, whereas there was increased corneal MDA content as compared with the control group. Treatment with D. salina could significantly (p<0.05) ameliorate corneal damage and increase the activities of SOD, catalase, GSH-Px, GSH-Rd, and GSH content, and decrease the MDA content in corneas when compared with the UVB-treated group. Conclusions: The studies demonstrate that D. salina exhibits potent protective effects on UVB radiation-induced corneal oxidative damage in mice, likely due to both the increase of antioxidant enzyme activity and the inhibition of lipid peroxidation. © 2012 Molecular Vision.


Tsai L.-F.,TransWorld University
International Journal of Digital Content Technology and its Applications | Year: 2011

The purpose of this study was to explore and analyze the Internet word-of-mouth of smartphones. The six main smartphone brands on the market were used as keywords to collect usage evaluations from users on blogs and cellphone forums between January 1, 2010 and July 20, 2011. After discarding unsuitable samples, the number of effective postings was 1002. The research results showed that the characteristics of Internet word-of-mouth of smartphone could be divided into two categories, the high brand competition area and the independent brand area. Based on an overview of the Internet word-of-mouth analysis on the smartphone market in Taiwan, it was suggested that vendors should emphasize photography, external appearance, and research and development of software functions in order to meet consumer needs. Good usage of brand marketing can strengthen the transmission of Internet word-of-mouth to elevate corporate interest.

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