Chen L.,University of Texas at San Antonio |
Petritis K.,Translational Genomics TGen Research Institute |
Tegeler T.,Translational Genomics TGen Research Institute |
Petritis B.,Arizona State University |
And 2 more authors.
Proceedings - 2011 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2011 | Year: 2011
A novel quantification method is proposed for labeled LC-MS data. Unlike the traditional extracted ion chromatogram based quantification methods, the new method considers the reliability or the quality of signals with different intensities and applies more weights to the more reliable signals in the relative quantification procedure. Testing shows that the new method has improved accuracy than current quantification software. © 2011 IEEE.