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Barcelona, Spain

Kayadjanian N.,Transbiomed | Burghes A.,Ohio State University | Finkel R.S.,Nemours Childrens Hospital | Mercuri E.,Catholic University | And 3 more authors.
Orphanet Journal of Rare Diseases | Year: 2013

Spinal muscular atrophy (SMA) is the most common lethal recessive disease in childhood, and there is currently no effective treatment to halt disease progression. The translation of scientific advances into effective therapies is hampered by major roadblocks in clinical trials, including the complex regulatory environment in Europe, variations in standards of care, patient ascertainment and enrolment, a narrow therapeutic window and a lack of biomarkers of efficacy. In this context, SMA-Europe organized its first international workshop in July 2012 in Rome, gathering 34 scientists, clinicians and representatives of patient organizations to establish recommendations for improving clinical trials for SMAa. © 2013 Kayadjanian et al.; licensee BioMed Central Ltd. Source

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Product for prostate cancer The standard screening tool for prostate cancer, the Prostate-Specific Antigen (PSA) blood test, does not specifically identify prostate cancer but also detects benign prostate hypertrophy and other conditions common among men. Approximately 66% of men with a suspicious PSA test do not have prostate cancer, upon subsequent analysis with a prostate biopsy ...

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Mission: to be a leader in the creation of new molecular diagnostics that are non-invasive, for diseases with significant unmet medical diagnostic needs and large markets. Tests will be for use in central reference laboratories initially Eventually tests may be developed for use at the point of care, in clinicians offices Business model: to identify and develop new molecular diagnostics through pivotal multi-center trials, and to license to larger companies for commercialization worldwide ...

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