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Wuhan, China

Liu Y.-J.,Wuhan University | Zhan J.,Wuhan University | Liu X.-L.,Wuhan University | Wang Y.,Tongji Medical College | And 2 more authors.
Clinical Nutrition | Year: 2014

Background & aims: Flavonoids may have cardioprotective effects, but epidemiological evidence on the relationship of dietary flavonoids with diabetes has not been systematically assessed. To examine the association between dietary flavonoids and type 2 diabetes, we performed a meta-analysis on this topic. Methods: We searched PubMed through March 2013 for relevant cohort studies that assessed total flavonoids and type 2 diabetes risks. A fixed-effect model was used to calculate the summary risk estimates. Results: Four articles consisting of 6 prospective cohorts that involved 18,146 cases and 284,806 participants were identified. The summary relative risk (RR) of type 2 diabetes for the highest intake of total flavonoids compared with the lowest was 0.91 (95% confidence interval (CI): 0.87-0.96). Furthermore, an increase in the total flavonoids intake of 500. mg/d was associated with a significant risk reduction of 5% (RR = 0.95, 95% CI: 0.91-0.98). In subgroup analyses, the observed beneficial effects were observed in US population, in those mean age > 40 years old people and in studies ≥20 years in duration. Conclusions: The present meta-analysis indicates that consumption of dietary total flavonoids is associated with a reduced risk of type 2 diabetes. © 2013 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. Source

Meng X.H.,Tongji Medical College
Zhonghua nan ke xue = National journal of andrology | Year: 2012

To observe the spermicidal effect of alcohol extracts from different ratios of Sophora flavescens Ait/Chinese Bulbul in vitro. Semen samples aseptically obtained by masturbation and prepared by density gradient centrifugation from 15 healthy men were incubated in the alcohol extracts from 9 different ratios of Sophora flavescens Ait/Chinese Bulbul for 20 seconds, 2 minutes and 4 minutes. Then the motility and movement parameters of the sperm were detected by computer-assisted semen analysis, and the minimal effective concentrations of the instant spermicidal effect of the extracts were determined. At the ratio of 3:1, the extract at 0.5 mg/ml significantly inhibited the sperm motility and other sperm movement parameters VCL, VSL, VAP, ALH, WOB and MAD, as compared with the control group. The minimal effective concentration of the instant spermicidal effect of the extracts was 3.5 mg/ml at 3:1. The alcohol extracts from Sophora flavescens Ait and Chinese Bulbul at the ratio of 3:1 have the best spermicidal effect in vitro. Source

Bishwajit G.,Tongji Medical College
International Journal of Agronomy | Year: 2014

This study aims to highlight the status of agricultural R&D in South Asia and contends that creating an effective agricultural research and innovation systems is a vital element to ensure food security in this region. South Asia is home to around one-fourth of mankind and houses the largest proportion of undernourished people in the world. Despite a period of marked economic growth averaging 6% a year over the past two decades, it remains the world's second poorest region contributing a mere 2.2% in global annual GDP. Agriculture is the mainstay of South Asian economy employing around 60% of the total workforce and generating around 20% of total GDP. South Asia has the recognition of being the second most food-insecure region next only to sub-Saharan Africa. Though there is growing evidence that technological innovation has a key role to play in increasing agricultural production and strengthening food security, agricultural research and development (R&D) sector has failed to garner sufficient attention till now. This study also depicts the current situation of food security in South Asia and illustrates how agricultural education and innovation hold the master key to solve the food security issues for the world's most densely populated region. © 2014 Ghose Bishwajit. Source

Ghoshal U.C.,Sanjay Gandhi Post Graduate Institute of Medical Sciences | Singh R.,Sanjay Gandhi Post Graduate Institute of Medical Sciences | Chang F.-Y.,Taipei Veterans General Hospital | Hou X.,Tongji Medical College | And 2 more authors.
Journal of Neurogastroenterology and Motility | Year: 2011

Dyspepsia is a syndrome consisting of epigastric pain, burning, fullness, discomfort, early satiety, nausea, vomiting and belching. Functional dyspepsia (FD) is diagnosed if upper gastrointestinal endoscopy does not show structural abnormality explaining these symptoms. 8%-30% and 8%-23% of Asian people suffer from of uninvestigated dyspepsia and FD, respectively. Most patients with uninvestigated dyspepsia are found to have FD. Patients with FD are usually young and there is no predilection to any gender. Overlap of FD with other functional bowel diseases such as irritable bowel syndrome and gastroesophageal reflux disease is common in Asia. Cultural difference in reporting of symptoms of dyspepsia is well-known. Moreover, dietary factors, socio-cultural and psychological issues, gastrointestinal infection including that caused by Helicobacter pylori, frequency of organic diseases such as peptic ulcer and gastric cancer responsible for dyspeptic symptoms in the study population may also influence epidemiology of dyspepsia. There is considerable heterogeneity in the above issues among different Asian countries. More studies on epidemiology of FD are needed in Asia. © 2011 The Korean Society of Neurogastroenterology and Motility. Source

Du T.,Tongji Medical College | Sun X.,PLA Fourth Military Medical University | Huo R.,Tongji Medical College | Yu X.,Tongji Medical College
International Journal of Obesity | Year: 2014

Background: The visceral adiposity index (VAI) and hypertriglyceridemic waist phenotype (the simultaneous presence of waist circumference (WC)≥90/80 cm for men/women and plasma triglyceride (TG) concentration≥1.7 mmol l -1 for both genders) have been identified as good indicators of visceral adiposity, which is an independent risk factor for diabetes. The Chinese population is characterized by a predominance of visceral fat accumulation despite having comparatively low weight. These two surrogate markers of visceral adiposity might effectively identify Chinese adults who are at risk of getting diabetes. We aimed to examine the association between VAI and risk of diabetes or between the hypertriglyceridemic waist phenotype and diabetes risk. Methods: We conducted a cross-sectional analysis of 7639 Chinese men and women aged ≥18 years using data from the China Health and Nutrition Survey 2009. Logistic regression was used to evaluate the associations. Results: For men, compared with participants in the lowest quartile of VAI scores, the multivariable-adjusted odds ratios (ORs) (with 95% confidence intervals) for diagnosed diabetes were 1.1 (0.7-1.7), 1.9 (1.3-2.8) and 3.6 (2.5-5.3) for those in the second, third, and top quartile of VAI scores, respectively. For women, the corresponding figures were 0.9 (0.5-1.4), 1.7 (1.1-2.6) and 2.8 (1.9-4.2), respectively. The multivariate-adjusted ORs (with 95% confidence intervals) for diabetes in men with the hypertriglyceridemic waist phenotype compared with men with both WC and TG measurements below the defined cut points were 3.7 (2.6-5.4). For women, the corresponding figure was 3.7 (2.4-5.5). For both men and women, the associations between the 4th quartile of VAI scores and risk of diabetes or between the hypertriglyceridemic waist phenotype and risk of diabetes were consistently seen in various subgroups. Conclusion: Among Chinese adults, high VAI scores and the hypertriglyceridemic waist phenotype are strongly associated with diabetes risk. © 2014 Macmillan Publishers Limited All rights reserved. Source

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