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Shanghai, China

Li W.,Heilongjiang University | Jiang K.,Heilongjiang University | Lin Z.,Tong University
Proceedings - 2012 International Conference on Computer Science and Information Processing, CSIP 2012 | Year: 2012

In this paper, a local discontinuous Galerkin (LDG) method is is designed for solving the BBM-Burgers equation with four-order spatial derivatives. Our schemes extend the previous work of Xu and Shu [8] solving the nonlinear Schrödinger equations on LDG method. The L 2 stability of the LDG methods is proved for general solutions. Numerical results are shown to illustrate the accuracy and capability of the LDG method. © 2012 IEEE. Source


Ding X.,Jiangnan University | Sun H.,Tong University | Gu X.,Jiangnan University
Chemical Vapor Deposition | Year: 2014

The experimental results of the direct deposition of graphene films on a gallium nitride (GaN)/sapphire substrate by catalyst-free atmospheric pressure (AP)CVD are presented. The quality and thickness of the synthesized samples can be controlled by the growth conditions. The prepared graphene/GaN samples show excellent optical transparency especially in the visible and infrared wavebands. The electrical transport properties are studied in the temperature range 4-300 K. The results indicate an advance step towards graphene-based applications in microelectronics and optoeletronics. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Source


Ke S.Z.,Xiamen University | Ni X.Y.,Xiamen University | Zhang Y.H.,Xiamen University | Wang Y.N.,Xiamen University | And 2 more authors.
International Journal of Oncology | Year: 2013

Multidrug resistance (MDR) formation is an important problem in lung cancer chemotherapy. Our study showed that both camptothecin and cisplatin could not only induce ATM and NF-κB activation but also upregulate expression of the MDR-related genes ABCG2, MRP2 in NCI-H446 cells. Moreover, camptothecin and cisplatin-induced ABCG2 and MRP2 upregulation could be impaired by ATM and NF-κB inhibitors, indicating a relationship between ATM, NF-κB activation and MDR formation in lung cancer chemotherapy. Our study indicates that ATM may serve as a potential molecular target for MDR formation in lung cancer chemotherapy. Source


Wu B.,Tong University | Li T.,Affiliated with the Kunming Medical College | Cai J.,Yangzhou University | Xu Y.,University of South China | Zhao G.,Shanghai JiaoTong University
BMC Cancer | Year: 2014

Background: To analyze and compare the economic outcomes of adjuvant chemotherapy with capecitabine plus oxaliplatin (referred to as the XELOX strategy) and of S-1 (the S-1 strategy) for gastric cancer patients after D2 gastrectomy. Methods: A Markov model was developed to simulate the lifetime disease course associated with stage II or III gastric cancer after D2 gastrectomy. The lifetime quality-adjusted life years (QALYs), associated costs, and incremental cost-effectiveness ratios (ICERs) were estimated. The clinical data were derived from the results of pilot studies. Direct costs were estimated from the perspective of the Chinese healthcare system, and the utility data were measured from end-point observations of Chinese patients. Sensitivity analyses were used to explore the impact of uncertainty on the model's outcomes. Results: The combined adjuvant chemotherapy strategy with XELOX yielded the greatest increase in QALYs over the course of the disease (8.1 QALYs compared with 7.8 QALYs for the S-1 strategy and 6.2 for surgery alone). The incremental cost per QALY gained using the XELOX strategy was significantly lower than that for the S-1 strategy ($3,502 vs. $6,837, respectively). The results were sensitive to the costs of oxaliplatin and the hazard ratio of relapse-free survival. Conclusion: The observations reported herein suggest that adjuvant therapy with capecitabine plus oxaliplatin is a highly cost-effective strategy and more favorable treatment option than the S-1 strategy in patients with stage II or III gastric cancer who have undergone D2 gastrectomy. © 2014 Wu et al. Source


Fang J.,Tongji University | Lian S.,Tong University | Lei X.,Tong University | Liu L.,Tong University
ICTIS 2015 - 3rd International Conference on Transportation Information and Safety, Proceedings | Year: 2015

Based on the irregularities measured data by track inspection car from Wen-Fu Passenger Dedicated Line of Nanchang railway bureau, the irregularity characteristics of middle and long wave irregularities with the wavelength range of 1∼50m was researched. By using of Welch methods the changing discipline of track irregularities power spectrum were analyzed. And the irregularities power spectrum fitting functions were studied by the least squares optimization algorithm. Track irregularities power spectrum of Wen-Fu Passenger Dedicated Line has been proposed. The analyzed results show: in analyzed wavelength range, the most track irregularities spectrum of passenger dedicated line are equal to or lower than Germany high-speed irregularities' spectrum. And only in small wavelength range, track irregularities spectrums of passenger dedicated line are higher than that of Germany high-speed irregularities. © 2015 IEEE. Source

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