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Bykova Iu.,Karlsruhe Institute of Technology | Weinhardt V.,University of Heidelberg | Weinhardt V.,Karlsruhe Institute of Technology | Kashkarova A.,Tomsk Polytechnic University | And 5 more authors.
Journal of Materials Science: Materials in Medicine | Year: 2014

The applications of synchrotron radiation (SR) in medical imaging have become of great use, particularly in angiography, bronchography, mammography, computed tomography, and X-ray microscopy. Thanks to recently developed phase contrast imaging techniques non-destructive preclinical testing of low absorbing materials such as polymers has become possible. The focus of the present work is characterization and examination of UHMWPE-derived materials widely used in medicine, before and after their exposure to SR during such testing. Physical properties, such as wettability, surface energy, IR-spectroscopy, roughness, optical microscopy, microhardness measurements of UHMWPE samples were studied before and after SR. The relationship between a growth of UHMWPE surface hydrophilicity after SR and surface colonization by stromal cells was studied in vitro. Obtained results demonstrate that SR may be used as prospective direction to examine bulk (porous) structure of polymer materials and/or to modify polymer surface and volume for tissue engineering. © 2014 Springer Science+Business Media.

Levitskii E.F.,Tomsk Institute of Balneology and Physiotherapy | Shilkina E.S.,Tomsk Institute of Balneology and Physiotherapy | Mustafina L.R.,Tomsk Institute of Balneology and Physiotherapy
Bulletin of Experimental Biology and Medicine | Year: 2010

Changes in liver structure in experimental CCl4-induced hepatitis depend on the phase of the circumannual cycle. Pronounced disorders in the liver with a model of toxic hepatitis were observed in winter and fall and minor changes were recorded in summer. In spring, the liver was characterized by higher adaptation and compensatory potential, its structural status spontaneously returned to normal on day 4 after the last injection of CCl 4. © 2010 Springer Science+Business Media, Inc.

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