Time filter

Source Type

Abe D.,Tokyo Metropolitan Matsuzawa Hospital | Arai M.,Tokyo Metropolitan Matsuzawa Hospital | Itokawa M.,Tokyo Metropolitan Institute of Medical Science
Schizophrenia Research | Year: 2016

Background/objectives: Previous studies have reported that people with schizophrenia have impaired emotional responses to music. Here we developed a simple music-based assay to assess patient's ability to associate a minor chord with sadness. We further characterize correlations between impaired musical responses and psychiatric symptoms. Method: We exposed participants sequentially to two sets of sound stimuli, first a C-major progression and chord, and second a C-minor progression and chord. Participants were asked which stimulus they associated with sadness, the first set, the second set, or neither. The severity of psychiatric symptoms was assessed using the Positive and Negative Syndrome Scale (PANSS). Study participants were 29 patients diagnosed with schizophrenia and 29 healthy volunteers matched in age, gender and musical background. Result: 37.9% (95% confidence interval [CI]:19.1-56.7) of patients with schizophrenia associated the minor chord set as sad, compared with 97.9% (95%CI: 89.5-103.6) of controls. Four patients were diagnosed with treatment-resistant schizophrenia, and all four failed to associate the minor chord with sadness. Patients who did not recognize minor chords as sad had significantly higher scores on all PANSS subscales. Conclusions: A simple test allows music-evoked emotions to be assessed in schizophrenia patient, and may show potential relationships between music-evoked emotions and psychiatric symptoms. © 2016.


Tagashira Y.,Tokyo Metropolitan Tama General Medical Center | Kozai Y.,Tokyo Metropolitan Tama General Medical Center | Yamasa H.,Tokyo Metropolitan Tama General Medical Center | Sakurada M.,Tokyo Metropolitan Tama General Medical Center | And 2 more authors.
Infection Control and Hospital Epidemiology | Year: 2015

Background. Rapidly growing nontuberculous mycobacteria (RGM) are considered rare pathogens, causing central line–associated bloodstream infection. We identified an outbreak of central line–associated bloodstream infection due to RGM at a hematology-oncology ward during a 5-month period. design. Outbreak investigation and literature review. setting. A Japanese tertiary care center. patients. Adults who were hospitalized at the hematology-oncology ward from October 15, 2011, through February 17, 2012. results. A total of 5 patients with a bloodstream infection due to RGM (4 cases of Mycobacterium mucogenicum and 1 case of Mycobacterium canariasense infection) were identified; of these, 3 patients had acute myeloid leukemia, 1 had acute lymphocytic leukemia, and 1 had aplastic anemia. Four of the 5 patients received cord blood transplantation prior to developing the bloodstream infection. All central venous catheters in patients with a bloodstream infection were removed. These patients promptly defervesced after catheter removal and their care was successfully managed without antimicrobial therapy. Surveillance cultures fromthe environment and water detected M. mucogenicum and M. canariasense in the water supply of the hematology-oncology ward. The isolates from the bloodstream infection and water sources were identical on the basis of 16S-rRNA gene sequencing. conclusions. The source of RGM in the outbreak of bloodstream infections likely was the ward tap water supply. Awareness of catheterrelated bloodstream infections due to nontuberculous mycobacteria should be emphasized, especially where immunocompromised patients are at risk. Also, using antimicrobials after catheter removal to treat central line–associated bloodstream infection due to RGM may not be necessary. © 2015 by The Society for Healthcare Epidemiology of America. All rights reserved.


Harima H.,Tokyo Metropolitan Matsuzawa Hospital
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica | Year: 2011

The term "acute psychosis" is commonly used as a provisional diagnosis in psychiatric acute settings, especially in emergency, when there is not sufficient information available to give a specific categorical diagnosis. The provisional diagnosis "acute psychosis" involves psychotic conditions with acute onset, psychotic conditions with unknown course and acute behavioural disorders with unknown subjective experiences. Because this provisional diagnosis is not a proper category, dimensional assessment of psychopathology including delusions, hallucinations, disorganization, mood/affect, catatonia and disorder of consciousness is required to start specific treatment. As "acute psychosis" is nosologically ill defined in the dichotomy of schizophrenia and mood disorder, traditional types such as bouffée délirante, cycloid psychoses and reactive psychosis are useful in practice as frames of reference. Because the provisional diagnosis of "acute psychosis" involves non-psychotic disorders such as adjustment disorders and personality disorders, the perspective of genetic understanding is helpful in making a non-dimensional differential diagnosis.


Okazaki Y.,Tokyo Metropolitan Matsuzawa Hospital
Nihon rinsho. Japanese journal of clinical medicine | Year: 2013

Recent development of understanding and psychiatric care on schizophrenia during past 30 years was reviewed. Slight brain volume reduction during early several years of the disease and association of psychotic symptoms with excess dopamine release in striatum were confirmed. A discovery of duration of untreated psychosis (DUP) has encouraged early intervention, hope for recovery from schizophrenia and liberation from old Kraepelin concept.


On 11 March 2011, the eastern part of Japan was struck by a magnitude 9.0 quake. About 20 000 people were killed or were missing, and a nuclear crisis followed. In Tokyo, people were indirectly exposed to the earthquake and nuclear crisis by TV broadcast. The aim of our study was to evaluate the potential effect of the series of catastrophes on psychiatric emergency hospitalizations in Tokyo. Clinical records of patients who were mandatorily admitted to Tokyo Metropolitan Matsuzawa Hospital by law because of urgent risk to self or others were reviewed. Records regarding the 2 years of investigation, which include the 6 months after the earthquake, were reviewed. The six months after the earthquake were compared with the eighteen months before the earthquake in clinical and demographic data using independent t-tests or χ(2) tests. During the 6 months before and after the earthquake, 97 and 127 people were mandatorily admitted. χ(2) Tests demonstrated a significant increase in the number of patients after the earthquake (P = 0.045), attributable to the significant increase in the number of patients with schizophrenia after the earthquake (P = 0.011, 32 vs 56), whereas there were no significant differences in the number of patients with other diagnoses between those two periods. Independent t-tests revealed that patients admitted after the earthquake had marginally significantly shorter periods of education compared with those admitted before the earthquake (13.78 vs 12.82 years, P = 0.084). This work suggests that patients with schizophrenia were more sensitive to indirect exposure to the earthquake and that a shorter period of education was a potential risk factor.


Osawa T.,Tokyo Metropolitan Matsuzawa Hospital
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica | Year: 2013

In a criminal court, the forensic psychiatrist is required to give a report that is easy to understand by the saiban-in (lay judge). However, a method to provide such a report has yet to be established. To extract and clarify the current problems with the saiban-in justice system, a questionnaire survey was conducted involving 19 forensic psychiatrists and 18 judges, public prosecutors, and lawyers. Based on the results of this survey, it is recommended that written reports from psychiatrists should be evaluated by legal professionals and psychiatrists, and points of controversy should be examined prior to the trial. In the hearing, a presentation by the psychiatrist should be made, and an oral testimony should follow.


Ishikura S.,Tokyo Metropolitan Matsuzawa Hospital
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica | Year: 2013

The Early Intervention Service in Tokyo Metropolitan Matsuzawa Hospital "wakaba" was established in November 2009. In order to promote engagement with clients and their families as soon as possible and to prevent disengagement from initial treatment, we regard the following four issues as important: 1. Provision of support to realize clients' aspirations as well as relief of symptoms 2. Allocation of care-coordinator to each client to provide care management 3. Assertive family intervention 4. Assertive outreach. The challenges that wakaba and the Japanese mental health system tackle include the improvement of the clinical staffs' skill, the innovation of the medical service fee system to realize a multi-disciplinary approach, the development of social resources which meet the needs of young patients, and definition of service components in Early Intervention.


Inoue K.,Aichi University | Fukunaga T.,Tokyo Medical Examiners Office | Okazaki Y.,Tokyo Metropolitan Matsuzawa Hospital
Journal of Forensic Sciences | Year: 2012

There were more than 30,000 suicides in 1998 in Japan, and since then, the numbers have remained high. In 2009, the number of suicides per a day was c.90. This phenomenon constitutes a major social problem. One of the major reasons for the rapid increase in the number of suicides appears to be the worsening economic problems. It is therefore necessary to research the relationship between economic issues and suicide. In this study, we examined the relationship between the value of the Nikkei Stock Average and suicide rates in Japan. The value of the Nikkei Stock Average may be related to suicide among men. On the basis of the results, relevant researchers and organizations should understand the factors that relate to suicide to better carry out specific suicide prevention measures. © 2012 American Academy of Forensic Sciences.


Tochigi M.,University of Tokyo | Nishida A.,Tokyo Metropolitan Institute of Medical Science | Shimodera S.,Kochi Medical School | Okazaki Y.,Tokyo Metropolitan Matsuzawa Hospital | Sasaki T.,University of Tokyo
European Child and Adolescent Psychiatry | Year: 2013

A number of studies have investigated seasonality of birth in schizophrenia. Most of the studies have consistently observed an excess of winter births, often associated with decreased summer births. We postulated that psychotic-like experiences (PLEs), subclinical hallucinatory and delusional experiences, may also be affected by birth season. In the present study, we assessed the season of birth effect on the prevalence of PLEs using data from the cross-sectional survey of 19,436 Japanese adolescents. As a result, significant excess of winter births was observed in the prevalence of PLEs, accompanied by a decreased proportion of summer births. The odds ratios for the prevalence of PLEs were estimated to be 1.11, which was on the same order with those for the development of schizophrenia in the previous meta-analytic studies. To our knowledge, this is the first to show the seasonality of birth in the prevalence of PLEs and implicate the winter birth effect on subclinical stage of schizophrenia. © 2012 The Author(s).


Niizato K.,Tokyo Metropolitan Matsuzawa Hospital
Nihon rinsho. Japanese journal of clinical medicine | Year: 2013

The function of each organ including the brain tends to decline with aging. This influences on the appearance of psychotic symptoms in the elderly. A manic state in the elderly is often atypical and different from that in younger and middle aged patients. Manic pseudodementia is an important symptom, which means that elderly manic patients easily show dementia-like behavior because of their Tatendrang(pressured action) or hyperkinesis, so they are misdiagnosed as having dementia. On medication, as the response to drugs is different to that in younger patients, side effects easily appear in the elderly. However, we have very few clinical-pharmacological data on the use of major tranquilizers including anti-manic drugs for elderly patients.

Loading Tokyo Metropolitan Matsuzawa Hospital collaborators
Loading Tokyo Metropolitan Matsuzawa Hospital collaborators