Hiratsuka, Japan
Hiratsuka, Japan

Tokai University is a private university in Tokyo, Japan. It was established in 1943 by Shigeyoshi Matsumae, who had formerly been the engineering president of the Ministry of Communications. The Shonan Campus was established in the 1960s.Tōkai University is unique amongst Japanese universities in referring to its faculties as "schools." Special features of the university include the Department of Nordic Studies, including instruction in languages. The university also offers pilot training in cooperation with All Nippon Airways. The university has focused particularly on the science and engineering, as the founder believed that "After the war, development and the peaceful use of the science and technology were necessary for the development of Japan where the resource was scarce" About 60 percent of students enrolled in those schools. Between 1994 and 2004, Tōkai University led all universities in Japan in the registration of new patents. Wikipedia.


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Patent
Tokai University and Toray Industries Inc | Date: 2015-04-20

A polymer laminate has 2-100 layers each containing a biodegradable resin and having a thickness of 10 nm-400 nm that are laminated, the thickness of at least one of the outermost layers is 10 nm-180 nm, and the outermost layers are joined to each other. A polymer laminate excellent in biocompatibility and mechanical strength and suitable to medical applications such as wound dressings and antiadhesive materials can be obtained.


Patent
Tokai University and Toray Industries Inc | Date: 2017-03-01

The present invention provides a polymer laminate in which 2-100 layers each containing a biodegradable resin and having a thickness of 10 nm-400 nm are laminated, the thickness of at least one of the outermost layers is 10 nm-180 nm, and the outermost layers are joined to each other. By the present invention, a polymer laminate excellent in biocompatibility and mechanical strength and suitable to medical applications such as wound dressings and antiadhesive materials can be obtained.


Grant
Agency: European Commission | Branch: FP7 | Program: CP-CSA | Phase: Fission-2013-3.4.1 | Award Amount: 5.53M | Year: 2013

COMET will strengthen the pan-European research initiative on the impact of radiation on man and the environment by facilitating the integration of radioecological research. COMET will build upon the foundations laid by the European Radioecology Alliance (ALLIANCE) and the on-going FP7 STAR Network of Excellence in radioecology. By collaborating with the European platforms on nuclear and radiological emergency response (NERIS) and low dose risk research (MELODI), COMET will significantly aid preparation for the implementation of the Horizon 2020 umbrella structure for Radiation Protection. In close association with STAR and the ALLIANCE, COMET will take forward the development of a Strategic Research Agenda as the basis for developing innovative mechanisms for joint programming and implementation (JPI) of radioecological research. To facilitate and foster future integration under a common federating structure, research activities developed within COMET will be targeted at radioecological research needs that will help achieve priorities of the NERIS and MELODI platforms. These research activities will be initiated in collaboration with researchers from countries where major nuclear accidents have occurred. Flexible funds, unallocated to specific tasks at project initiation, have been included within the COMET budget to facilitate RTD activities identified through the JPI mechanisms developed that are of joint interest to the ALLIANCE, NERIS and MELODI. It will also strengthen the bridge with the non-radiation community. Furthermore, COMET will develop strong mechanisms for knowledge exchange, dissemination and training to enhance and maintain European capacity, competence and skills in radioecology. The COMET consortium has 13 partners, expanding from the organisations within the FP7 STAR project. In particular, COMET partners from countries which have experienced major nuclear accidents (i.e. Ukraine and Japan) and/or who hold Observatory sites.


Ishimoto H.,Tokai University | Jaffe R.B.,University of California at San Francisco
Endocrine Reviews | Year: 2011

Continuous efforts have been devoted to unraveling the biophysiology and development of the human fetal adrenal cortex, which is structurally and functionally unique from other species. It plays a pivotal role, mainly through steroidogenesis, in the regulation of intrauterine homeostasis and in fetal development and maturation. The steroidogenic activity is characterized by early transient cortisol biosynthesis, followed by its suppressed synthesis until late gestation, and extensive production of dehydroepiandrosterone and its sulfate, precursors of placental estrogen, during most of gestation. The gland rapidly grows through processes including cell proliferation and angiogenesis at the gland periphery, cellular migration, hypertrophy, and apoptosis. Recent studies employing modern technologies such as gene expression profiling and laser capture microdissection have revealed that development and/or function of the fetal adrenal cortex may be regulated by a panoply of molecules, including transcription factors, extracellular matrix components, locally produced growth factors, and placenta-derived CRH, in addition to the primary regulator, fetal pituitary ACTH. The role of the fetal adrenal cortex in human pregnancy and parturition appears highly complex, probably due to redundant and compensatory mechanisms regulating these events. Mounting evidence indicates that actions of hormones operating in the human feto-placental unit are likely mediated by mechanisms including target tissue responsiveness, local metabolism, and bioavailability, rather than changes only in circulating levels. Comprehensive study of such molecular mechanisms and the newly identified factors implicated in adrenal development should help crystallize our understanding of the development and physiology of the human fetal adrenal cortex. © 2011 by The Endocrine Society.


Patent
Foundation For Biomedical Research And Innovation, Tokai University, Stemmed Inc. and Juntendo Educational Foundation | Date: 2015-08-05

Simplification of a preparation step of a cell population used for the treatment of ischemic diseases, and provision of a cell population that shows more effect by the treatment. A method of producing a cell population wherein a vascular endothelial progenitor cell and/or an anti-inflammatory macrophage are/is enriched, including cultivating a mononuclear cell derived from bone marrow, cord blood or peripheral blood in a serum-free medium containing stem cell factor, interleukin-6, FMS-like tyrosine kinase 3 ligand, thrombopoietin and vascular endothelial cell growth factor, and proliferating vascular endothelial progenitor cell from the cell; and a cell population obtained by the method, etc.


Patent
Tokai University and Nissan Chemical Industries Ltd. | Date: 2016-08-31

There is a method for producing an optical waveguide composing an optical path conversion component having an extremely low signal loss, allowing a high surface packaging density and high speed operation, and allowing high productivity. A method for producing an optical waveguide that propagates light from a surface of a support to an oblique direction not vertical to the surface, the method for producing an optical waveguide comprising the steps of: (1) providing an anti-reflective coating on the support; (2) placing a photosensitive resin composition on the anti-reflective coating, and exposing the photosensitive resin composition to a light ray entering from a direction non-vertical to the surface of the support through a photomask for curing the composition; and (3) removing the unexposed photosensitive resin composition by development; and an optical waveguide obtained by the method.


Patent
Tokai University and Nissan Chemical Industries Ltd. | Date: 2014-10-16

A method for producing an optical waveguide composing an optical path conversion component having an extremely low signal loss, allowing a high surface packaging density and high speed operation, and allowing high productivity. A method for producing an optical waveguide that propagates light from a surface of a support to an oblique direction not vertical to the surface, the method for producing an optical waveguide comprising the steps of: (1) providing an anti-reflective coating on the support; (2) placing a photosensitive resin composition on the anti-reflective coating, and exposing the photosensitive resin composition to a light ray entering from a direction non-vertical to the surface of the support through a photomask for curing the composition; and (3) removing the unexposed photosensitive resin composition by development; and an optical waveguide obtained by the method.


Matsushita M.,Tokai University
Molecular Immunology | Year: 2013

Ficolins are a group of multimeric lectins made up of single subunits each of which is composed of a collagen-like domain and a fibrinogen-like domain. Most of the ficolins identified to date bind to acetylated compounds such as N-acetylglucosamine (GlcNAc) and N-acetylgalactosamine (GalNAc). Ficolins in serum are complexed with MBL-associated serine proteases (MASPs) and their truncated proteins. These lectins play an important role in innate immunity. Binding of the ficolin-MASP complex to carbohydrates present on the surface of microbes initiates complement activation via the lectin pathway. © 2012 Elsevier Ltd.


An effective long-haul self-mixing interference effect has been observed in a thin-slice LiNdP4O12 (LNP) laser due to Doppler-shifted optical feedback from a distant target. The narrow spectral linewidth of the LNP laser, which was evaluated to be 16 kHz by heterodyne measurements, led to successful self-mixing laser Doppler velocimetry and vibrometry of targets placed 2.5 km away from the laser through single-mode optical fiber access. © 2014 Optical Society of America.


Patent
Tokai University and Nipro Corporation | Date: 2016-03-30

Provided is a stent having a novel structure, the stent simultaneously having both the stability of shape against the action of external force, such as compression force, tensile force, or torsional force, and high flexibility in the direction of twisting of the stent. Connection groups (20) are provided at three or more positions set at circumferentially equally-spaced intervals, the connection groups (20) each comprising connection sections (14) which are disposed circumferentially close to each other between axially adjacent tubular divided bodies (12c). The connection groups on both sides axially of each of the tubular divided bodies (12c) are provided at positions circumferentially offset from each other while at least one turning portion (18) is present between the connection groups.

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