Sendai, Japan
Sendai, Japan

Tohoku University , Tōhoku daigaku), abbreviated to Tohokudai , located in Sendai, Miyagi in the Tōhoku Region, Japan, is a Japanese national university. It is the third oldest Imperial University in Japan and among the National Seven Universities. It is considered as one of the most prestigious universities in Japan, and one of the top fifty universities in the world.In 2009, Tohoku University had ten colleges within the university, including fifteen departments with graduate students, with a total enrollment of 17,949 students. The university's three core values are "Research First ," "Open-Door ," and "Practice-Oriented Research and Education ." Wikipedia.

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Patent
Kyoto University, Tohoku University and Ohki | Date: 2017-03-29

The present invention provides a method for preparing a graft material containing organ or tissue cells, the cells including cells having inhibited PHLDA3 expression.


Patent
Tohoku University and Mitaya Manufacturing Co. | Date: 2017-03-08

The present invention provides an evaluation aid which can be used as a phantom (imitation lesion) when a digital X-ray dynamic image thereof is taken and then evaluation is carried out through the digital X-ray dynamic image, and especially an evaluation aid which can be used for evaluating image qualities of a digital X-ray dynamic image for X-ray absorption parts having different X-ray absorption ratios, and an evaluation device provided with such an evaluation aid. The evaluation aid of the present invention is adapted to be used for taking a digital X-ray dynamic image thereof through which evaluation is carried out, and contains a fixed plate (plate-like body) including a plurality of regions having different X-ray absorption ratios; a rotating disk (movable body) having a plurality of wires (wire rods), the rotating disk capable of rotating (moving) with respect to the fixed plate so that the plurality of wires traverse X-ray with which the fixed plate is irradiated; and a driving motor (driving portion) which rotates (moves) the rotating disk with respect to the fixed plate. It is preferred that thicknesses and/or constituent materials of the plurality of regions of the fixed plate are different from each other, so that these regions have the different X-ray absorption ratios.


Patent
Furukawa Electric Group, Furukawa Techno Material Co. and Tohoku University | Date: 2017-01-18

{Problems} For providing a Cu-Al-Mn-based alloy material which has excellent resistance to repeated deformations, for providing a method of producing the same, and for providing a rod material or a sheet material using the alloy material. {Means to solve} A Cu-Al-Mn-based alloy material (1) having a composition containing 3.0 to 10.0 mass% of Al, 5.0 to 20.0 mass% of Mn, and a given total content of at least one selected from the group consisting of Ni, Co, Fe, Ti, V, Cr, Si, Nb, Mo, W, Sn, Mg, P, Be, Sb, Cd, As, Zr, Zn, B, C, Ag, and misch metal, each of which is contained in a given content; with the balance being Cu and unavoidable impurities, wherein the alloy material is an alloy material having a shape that is elongated in the working direction (RD), which is the rolling direction or the wire-drawing direction, wherein in regard to a grain X (2) for which the grain length a_(x) in the working direction of the alloy material is R/2 or less with respect to the width or diameter (R) of the alloy material, and for which the grain length b_(x) in a direction perpendicular to the working direction is R/4 or less, the amount of existence of the grains X is 15% or less of the total amount of the alloy material, and wherein in regard to a grain Y (3), for which the grain length a in the working direction and the grain length b in the direction perpendicular to the working direction satisfy: a b, and for which the angle formed by the normal line of the (111) plane of that crystal and the working direction is 15 or larger, the amount of existence of the grains Y is 85% or more of the total amount of the alloy material; a method of producing the same; and a rod or sheet material using the alloy material.


Patent
Tohoku University, Gunma University and Fuso Pharmaceutical Industries Ltd. | Date: 2017-01-04

The present invention provides a useful medicament for the treatment and/or prophylaxis of a disease associated with the enhancement of OPN production including cancer, which comprises a compound of formula:^(1), R^(2), R^(3), R^(4), R^(5), R^(6), R^(7), m, n, p, X, and Y are as defined in the specification, or a pharmaceutically acceptable salt thereof.


Patent
Ngk Insulators and Tohoku University | Date: 2017-03-01

A method for manufacturing a copper alloy according to the present invention comprises (a) weighing a copper powder and one of a Cu-Zr master alloy and a ZrH_(2) powder such that an alloy composition of Cu-xZr (x is the atomic% of Zr, and 0.5 x 8.6 is satisfied) is obtained and pulverizing and mixing the copper powder and the one of the Cu-Zr master alloy and the ZrH_(2) powder in an inert atmosphere until an average particle diameter D50 falls within the range of from 1 m to 500 m to thereby obtain a powder mixture; and (b) subjecting the powder mixture to spark plasma sintering by holding the powder mixture at a prescribed temperature lower than eutectic temperature while the powder mixture is pressurized at a pressure within a prescribed range.


Patent
Tohoku University | Date: 2017-03-01

A primary object of the present invention is to provide a method for conveniently and accurately testing for pulmonary hypertension. To achieve this object, the present invention provides a method for testing for pulmonary hypertension using as an indicator the concentration of selenoprotein P protein in a sample derived from a subject.


Patent
Tohoku University and IHI Corporation | Date: 2017-03-22

Provided is a combustion experiment device (1), which includes a reaction tube (2) into which a sample fluid (X) flows and to which a temperature gradient in which a temperature rises toward a downstream side is imparted, and a burner part (4) that is configured to flow a combustible gas (Y) along and around the reaction tube from the downstream side to an upstream side of the reaction tube and to maintain a flame (F) surrounding the reaction tube from the outside in a radial direction of the reaction tube.


Patent
University of Tokyo, Tohoku University and Shionogi & Co. | Date: 2017-01-04

The present invention provides a compound of formula (I), wherein R^(1), R^(2), R^(3), R^(4a), R^(4b), R^(5a) and R^(5b) are as defined in the description, which has an autotaxin inhibitory activity, a pharmaceutical composition comprising the compound as an active ingredient, and a method of prevention or treatment of a disease involving autotaxin, which is characterized by administering the compound.


Patent
Clio Inc. and Tohoku University | Date: 2017-01-23

An object of the present invention is to provide a novel medical application to regenerative medicine that uses pluripotent stem cells (Muse cells). The present invention provides a cell preparation for treating cerebral infarction and sequelae associated therewith that contains SSEA-3-positive pluripotent stem cells isolated from mesenchymal tissue in the body or cultured mesenchymal cells. The cell preparation of the present invention is based on a brain tissue regeneration mechanism by which Muse cells differentiate into nerve cells and the like in damaged brain tissue by administering Muse cells into cerebral parenchyma.


Patent
Clio Inc. and Tohoku University | Date: 2017-01-23

An object of the present invention is to provide a novel medical application to regenerative medicine that uses pluripotent stem cells (Muse cells). The present invention provides a cell preparation for treating chronic kidney disease that contains SSEA-3-positive pluripotent stem cells isolated from mesenchymal tissue in the body or cultured mesenchymal cells. The cell preparation of the present invention is based on a renal tissue regeneration mechanism by which Muse cells are made to selectively accumulate at a site of kidney disease and differentiate into cells that compose the kidney by administering Muse cells intravenously to a subject having the aforementioned disease.

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